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Overview

Alteplase

Prescription vs OTC : Prescription by Doctor required

About Alteplase

Alteplase belongs to a group of drugs called thrombolytics and they dissolve blood clots quickly. It helps restart blood flow to the heart and also helps prevent damage to the heart muscle. In simple words we can say that this medicine helps in dissolving blood clots.

This medication is available in an injectable dosage form to be given directly intravenously by a health care professionals. A common side effect of this medication is bleeding.

Do not take alteplase if you:
  • are allergic to alteplase or any of its ingredients
  • have an active bleed
  • have a history of a brain injury
  • have had recent major surgery or trauma especially in the head
  • severely uncontrolled high blood pressure
  • have or have had any problems managing bleeding conditions in the past

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

    What are the uses of Alteplase

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

    What are the contraindications of Alteplase ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

    What are the side effects of Alteplase ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

    Key highlights of Alteplase

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      This medication may be unsafe to use during pregnancy.

    • Are there any breast-feeding warnings?

      This medication is probably safe to use during lactation.

    • Is it safe to drive while on this medicine?

      Not relevant, as this medication is intended for use in hospitalised patients.

    • Does this affect kidney function?

      This medication is probably safe to use in patients with kidney disease.

    • Does this affect liver function?

      There is limited information available on the use of this medication in patients with liver disease.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    • Are there any missed dose instructions?

      If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

    Medicines containing Alteplase

    Below is the list of medicines, which contains Alteplase as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

    How does this medication work?

    This medication belongs to one of the kinds of blood thinner, primarily used to treat myocardial infarctions and other clotting disorders. The fibrin rich clots are bound by the drug, through the Kringle 2 and fibronectin domain.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

      What are the interactions of Alteplase ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medicine interacts with the following medicines which includes coumarine derivatives, oral anticoagulants, platelet aggregation inhibitors, unfractionated heparin or LMWH and ACE inhibitors.

      FAQs about Alteplase

      • Ques : What is Alteplase?

        Ans : This medication belongs to a group of drugs called thrombolytics and they dissolve blood clots quickly.

      • Ques : How long do I need to use Alteplase before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Alteplase?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Alteplase empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Alteplase?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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