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Overview

Themikool Tablet

Manufacturer :  Themis Medicare Ltd
Medicine Composition :  Rabeprazole
Prescription vs OTC : Prescription by Doctor required

About Themikool Tablet

Themikool Tablet is prescribed for the short-term (4-8 weeks) treatment of erosive esophagitis associated with gastroesophageal diseases (GERD). It is also helpful in treating peptic ulcers, acid reflux, and Zollinger-Ellison syndrome.

This proton-pump inhibitor reduces the amount of naturally occurring acid in the stomach. It helps by preventing esophagus being damaged by the acids and treating peptic ulcers in the digestive system.

The tablet also helps in the treatment of stomach ulcers caused by the bacteria called Helicobacter pylori. It is important that you stick to the dosage prescribed by the doctor to avoid any serious side effects. When taking the tablet, make sure that you do not miss a dose.

Some of the side effects of this drug are joint pain, dizziness, vomiting, abdominal pain, diarrhea, and headache. Other serious side effects include anxiety, irregular heartbeat, severe diarrhea, seizures, muscle spasms, tremors, and lupus or kidney damage. If you experience any of it, consult a doctor immediately.

There has been no experience with large overdoses with Themikool Tablet. Seven reports of accidental overdosage with rabeprazole have been received. The maximum reported overdose was 80 mg.

There were no clinical signs of symptoms associated with any reported overdose. Patients with Zollinger-Ellison syndrome have been treated with up to 120 mg/day. No specific antidote for rabeprazole is known. The single oral dose of 2000 mg/kg was not lethal to dogs.

Patient must swallow whole Themikool Tablet- do not crush, chew, or split tablet; take before eating.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the uses of Themikool Tablet

    • Erosive Esophagitis

    • Gastroesophageal Reflux Disease

    • Helicobacter Pylori Infection

    • Zollinger-Ellison Syndrome

    • Other Forms Of Ulcers

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the contraindications of Themikool Tablet ?

    • Allergy

      Themikool Tablet is not advised for use if you have a known history of allergy to it.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the side effects of Themikool Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    Key highlights of Themikool Tablet

    • How long is the duration of effect?

      The effect lasts for an average duration of about 24 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed after 1-2 hours of administration.

    • Are there any pregnancy warnings?

      This medicine is not recommended for use in pregnant women owing to the risk of abnormalities in the fetus.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for use in breastfeeding women owing to the risk of adverse effects on the baby.

    • Does this affect kidney function?

      No relevant data available.

    • Does this affect liver function?

      No relevant data available.

    • Is It safe with alcohol?

      Caution must be taken in consuming alcohol while taking this medication.

    • Is it safe to drive while on this medicine?

      This fact is not known, whether this medicine will affect the ability of driving of the patient. Kindly consult your doctor before taking this.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the substitutes for Themikool Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Themikool Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

    • Are there any overdose instructions?

      Contact a doctor immediately if an overdose is suspected. Some overdosages could lead to Lactic Acidosis which requires immediate medical intervention.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    Where is the Themikool Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    How does this medication work?

    This medication is a proton pump inhibitor drug and binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

      What are the interactions of Themikool Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Avoid using alcohol while taking this medicine. Symptoms such as prolonged weakness and muscle pain, lack of sleep, breathing difficulties after alcohol intake should be reported to the doctor immediately.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        Do not use Themikool Tablet in combination with Ketoconazole, Phenytoin, Warfarin, Nelfinavir and Digoxin.
      • Interaction with Food

        Information not available.
      • Interaction with Disease

        Those who suffer from liver disease, Osteoporosis and magnesium level imbalance must tell their doctor before using Themikool Tablet.

      FAQs about Themikool Tablet

      • Ques : What is Themikool Tablet?

        Ans : This medication is prescribed for the treatment of gastrointestinal disorders like gastroesophageal diseases or GERD, peptic ulcers, acid reflux, and Zollinger-Ellison syndrome.

      • Ques : How long do I need to use Themikool Tablet before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Themikool Tablet?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Themikool Tablet empty stomach, before food or after food?

        Ans : This medication should be taken prior to the meal, approximately 30 minutes before it, in the prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Themikool Tablet?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : What are the effects of Themikool Tablet older adults?

        Ans : Proton pump inhibitors (such as Themikool Tablet) may increase the risk for bone fractures, especially with longer use, higher doses in older adults. Consult your doctor about ways to prevent bone loss/fracture.

      • Ques : Can I take this medicine along with other medications to improve the clinical symptoms?

        Ans : Yes, if needed, antacids may be taken along with this medication. If you are taking sucralfate, take Themikool Tablet at least 30 minutes before sucralfate. These two can alleviate the clinical symptoms of the disease.

      • Ques : Is it safe to use Themikool Tablet for a long period of time?

        Ans : It is advised to use this drug for the duration advised by your doctor.

      • Ques : Does Themikool Tablet cause bone problems?

        Ans : Yes, long term use of this drug can cause thinning of bones, which is called osteoporosis.

      • Ques : Can I take Themikool Tablet with vitamin D?

        Ans : Yes, vitamin D can be taken along with this drug. It is generally advised to be taken as a supplement with this drug as the long term use of Themikool Tablet decreases the absorption of calcium and may lead to calcium deficiency.

      References

      • Rabeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 23 Nov 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/117976-89-3

      • PARIET 20mg- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 23 Nov 2021]. Available from:

        https://www.medicines.org.uk/emc/product/7867/smpc

      • RABEPRAZOLE SODIUM tablet, delayed release- Daily Med [Internet]. dailymed.nlm.nih.gov. 2020 [Cited 23 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d11c3211-b4d4-4893-8c1c-b8fb6d0a0b89

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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