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Overview

Nikoran 2Mg Injection

Manufacturer :  Torrent Pharmaceuticals Ltd
Medicine Composition :  Nicorandil
Prescription vs OTC : Prescription by Doctor required

About Nikoran 2Mg Injection

Nikoran 2Mg Injection is a vasodilatory drug. It treats angina chest pain. This medication widens blood vessels thus increasing the blood and oxygen flow to the heart. This medication is used to treat other heart conditions also.

On using Nikoran 2Mg Injection you may experience side effects such as rapid or irregular heartbeat, swelling, darkening of urine, dizziness, headache, nausea, fatigue, a decrease in blood pressure levels, flushes, skin rash, high potassium levels, muscle pain or stomach pain. Notify your physician if you face any of these effects.

Before using this medication tell your doctor if you are allergic to any of the ingredients contained within Nikoran 2Mg Injection, having any other allergies, already taking any medications, have low blood pressure, skin/ mouth ulcers, heart problems or pulmonary oedema, are pregnant or are breastfeeding a baby.

The dosage should be prescribed by your doctor based on your medical history and current condition. The usual dose in adults is about 10 mg twice a day which may be increased to 20 mg depending on your response.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the uses of Nikoran 2Mg Injection

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the contraindications of Nikoran 2Mg Injection ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the side effects of Nikoran 2Mg Injection ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    Key highlights of Nikoran 2Mg Injection

    • Is It safe with alcohol?

      It is unsafe to consume alcohol while taking this medicine.

    • Are there any pregnancy warnings?

      Nikoran 2Mg Injection may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Nikoran 2Mg Injection is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Does this affect kidney function?

      There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    • Is it safe to drive while on this medicine?

      This medicine might affect the consciousness of the patient. Thus driving must be avoided while taking Nikoran 2Mg Injection.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Nicorandil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    How does this medication work?

    This medication works following the dual mechanism. Firstly, it activates the ATP sensitive potassium channel, leading to vascular smooth muscle hyperpolarization. Secondly, it triggers guanylate cyclase to enhance the production of cyclic GMP, thereby activating protein kinase G. Therefore, GTPase RhoA is inhibited and Rho-kinase activity is decreased. As a result, the myosin phosphatase activity is accelerated and the calcium sensitivity of the smooth muscle is reduced. Owing to its nitrate property, nicorandil works as a vasodilator.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

      What are the interactions of Nikoran 2Mg Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medication interacts with Corticosteroids, Riociguat, NSAIDs, Phosphodiesterase 5 (PDE) inhibitors, and Vasodilators.
      • Interaction with Disease

        This medication interacts with Gastrointestinal Disorders.

      FAQs about Nikoran 2Mg Injection

      • Ques : What is Nikoran 2Mg Injection?

        Ans : AnsNikoran 2Mg Injection is a vasodilatory drug. It treats angina chest pain. This medication widens blood vessels thus increasing the blood and oxygen flow to the heart.

      • Ques : What are the uses of Nikoran 2Mg Injection?

        Ans : Ans Nikoran 2Mg Injection is used for the control and treatment of Chest Pain.

      • Ques : What are the side effects of this Nikoran 2Mg Injection?

        Ans : On using Nikoran 2Mg Injection you may experience side effects such as rapid or irregular heartbeat, swelling, darkening of urine, dizziness, headache, nausea, fatigue, a decrease in blood pressure.

      • Ques : How long do I need to use Nikoran 2Mg Injection before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Nikoran 2Mg Injection?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Nikoran 2Mg Injection empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Nikoran 2Mg Injection?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : How is this Nikoran 2Mg Injection administered?

        Ans : This medication is administered orally.

      References

      • Nicorandil-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 14 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/nicorandil

      • Nicorandil-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 14 June 2022].Available from:

        https://go.drugbank.com/drugs/DB09220

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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