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Overview

Dexona 0.5 MG Tablet

Manufacturer :  Zydus Cadila
Medicine Composition :  Carbamazepine
Prescription vs OTC : Prescription by Doctor not required

About Dexona 0.5 MG Tablet

Dexona 0.5 MG Tablet essentially treats nerve pain like trigeminal neuralgia as well as diabetic neuropathy. Moreover, the drug also effectively treats bipolar disorder. Dexona 0.5 MG Tablet functions as an anticonvulsant and decreases the occurrence of abnormal nerve impulses in the brain which can lead to severe reactions like seizures and acute pain.

Unlabeled uses: Treat bipolar disorders and other affective disorders, resistant schizophrenia, alcohol withdrawal, restless leg syndrome, psychotic behavior associated with dementia, post-traumatic stress disorders.

The effect of the medicine is quite slow and does lead to some side effects; it may take about a couple of weeks or more for your condition to improve. The medicine should be taken as prescribed, as directions of the doctor should be adhered to strictly.

Before starting the drug make sure to give your doctor detailed information about any existing health issues and allergies. Before taking this medication to inform the doctor, if you are or suffer from:

  • Heart problems
  • Thyroid issues
  • Porphyria
  • Lupus
  • Mental illness
  • Kidney problem
  • Pregnant or going to become pregnant

If you are on the drug during your pregnancy make sure to clearly follow the doctor’s instructions on dosage and consumption. Do not stop the drug or increase dosage without the doctor’s advice as it can cause severe complications for the baby.

Take exactly as directed (do not increase dose or frequency or discontinue without consulting prescriber). While using this medication, do not use alcohol and other prescription or OTC medications (especially pain medications, sedatives, antihistamines, or hypnotics) without consulting prescriber.

Symptoms of overdose include dizziness ataxia, drowsiness, nausea, vomiting, tremor, agitation, nystagmus, urinary retention, dysrhythmias, coma, seizures, twitches, respiratory depression, neuromuscular disturbances.

Provide general supportive care. Activated charcoal is effective at binding certain chemicals and this is especially true for carbamazepine; other treatment is supportive/symptomatic. Treatment consists of inducing emesis or gastric lavage. EKG should also be monitored to detect cardiac dysfunction. Monitor blood pressure, body temperature, pupillary reflexes, bladder function for several days following ingestion.

    What are the uses of Dexona 0.5 MG Tablet

    What are the contraindications of Dexona 0.5 MG Tablet ?

    What are the side effects of Dexona 0.5 MG Tablet ?

    Key highlights of Dexona 0.5 MG Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 2 to 3 days.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 4.5 hours for immediate-release tablets, 3 to 12 hours for extended-release tablets and 1.5 hours for oral suspension.

    • Are there any pregnancy warnings?

      Dexona 0.5 MG Tablet crosses the placenta. Dysmorphic facial features, cranial defects, cardiac defects, spina bifida, IUGR, and multiple other malformations reported. Epilepsy itself, number of medications, genetic factors, or a combination of these probably influence the teratogenicity of anticonvulsant therapy. Benefit:risk ratio usually favors continued use during pregnancy and breast-feeding. Inform prescriber if you are or intend to be pregnant.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Dexona 0.5 MG Tablet crosses into breast milk. American Academy of Pediatrics considers compatible with breastfeeding.

    • Is It safe with alcohol?

      It id found to be unsafe when taken with alcohol.

    • Is it safe to drive while on this medicine?

      It might cause side effects that could affect the alertness of the patient. Hence affect the ability of the patient. If the patient is taking this medicine, driving must be avoided.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Modification in dose is needed. Dosing adjustment in renal impairment:

      • Clcr <10 mL/minute: Administer 75% of dose.

    • Does this affect liver function?

      Caution must be taken in patients with liver disease. Dose adjustment might be needed. Kindly consult your doctor before taking this medicine.

    What are the substitutes for Dexona 0.5 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Dexona 0.5 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    How does this medication work?

    In addition to anticonvulsant effects, Dexona 0.5 MG Tablet has anticholinergic, antineuralgic, antidiuretic, muscle relaxant and antiarrhythmic properties; may depress activity in the nucleus ventralis of the thalamus or decrease synaptic transmission or decrease summation of temporal stimulation leading to neural discharge by limiting influx of sodium ions across cell membrane or other unknown mechanisms; stimulates the release of ADH and potentiates its action in promoting reabsorption of water; chemically related to tricyclic antidepressants.

      What are the interactions of Dexona 0.5 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
      • Interaction with Lab Test

        Dexona 0.5 MG Tablet might lead to increase BUN, AST, ALT, bilirubin, alkaline phosphatase (S); and decrease calcium, T3, T4, sodium (S) levels.
      • Interaction with Medicine

        • Dexona 0.5 MG Tablet may induce the metabolism of benzodiazepines, citalopram, clozapine, corticosteroids, cyclosporine, doxycycline, ethosuximide, felbamate, felodipine, haloperidol, mebendazole, methadone, oral contraceptives, phenytoin, tacrolimus, theophylline, thyroid hormones, tricyclic antidepressants, valproic acid, warfarin; monitor for altered response; dose adjustment may be needed.
        • Cimetidine, clarithromycin, danazol, diltiazem, erythromycin, felbamate, fluoxetine, fluvoxamine, isoniazid, lamotrigine, metronidazole, propoxyphene, verapamil, fluconazole, itraconazole, and ketoconazole may inhibit hepatic metabolism of Dexona 0.5 MG Tablet with resultant increase of carbamazepine serum concentrations and toxicity.
        • CBZ may enhance hepatotoxic potential of acetaminophen.
        • Neurotoxicity may result in patients receiving lithium and CBZ concurrently.
      • Interaction with Disease

        MAO inhibitors should be discontinued for a minimum of 14 days before carbamazepine is begun; administer with caution to patients with history of cardiac damage or hepatic disease; potentially fatal blood cell abnormalities have been reported following treatment; early detection of hematologic change is important; advise patients of early signs and symptoms including fever, sore throat, mouth ulcers, infections, easy bruising, petechial or purpuric hemorrhage; carbamazepine is not effective in absence, myoclonic or akinetic seizures; exacerbation of certain seizure types have been seen after initiation of carbamazepine therapy in children with mixed seizure disorders. Elderly may have increased risk of SIADH-like syndrome.
      • Interaction with Food

        Dietary consideration

        • Drug may cause GI upset, take with large amount of water or food to decrease GI upset. May need to split doses to avoid GI upset.
        • Sodium: SIADH and water intoxication; monitor fluid status; may need to restrict fluid.

      FAQs about Dexona 0.5 MG Tablet

      • Ques : What is Dexona 0.5 MG Tablet?

        Ans : This medication functions as an anticonvulsant and decreases the occurrence of abnormal nerve impulses in the brain.

      • Ques : What are the uses of Dexona 0.5 MG Tablet?

        Ans : This medicine is an anti-epileptic drug that is useful in treating fits (seizures). It is also used to cure trigeminal neuralgia (intense facial nerve pain).

      • Ques : How long do I need to use Dexona 0.5 MG Tablet?

        Ans : This medication is to be taken till the time you see an improvement in your health.

      • Ques : Should I use Dexona 0.5 MG Tablet empty stomach, before food or after food?

        Ans : This medication should be taken after food or prescribed by the doctor.

      • Ques : What are the instructions for the storage and disposal of Dexona 0.5 MG Tablet?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : Is Dexona 0.5 MG Tablet an analgesic?

        Ans : Dexona 0.5 MG Tablet is not a type of analgesic drug, hence, it must not be used in case of regular pain.

      • Ques : What are the long-term effects of Dexona 0.5 MG Tablet?

        Ans : The long-term side effects of this drug vary from one person to another. Some people can tolerate the drug for years, others develop side effects when consumed for a longer duration.

      • Ques : How do I stop taking Dexona 0.5 MG Tablet?

        Ans : You must not stop this medicine without consulting a doctor. In case you want to stop it, it is suggested to lower down the dosage gradually.

      • Ques : How quickly does Dexona 0.5 MG Tablet start working?

        Ans : It takes about 14 days to see improvement in this condition. Consult your doctor if you don’t see improvement even after completing the full course of treatment.

      • Ques : What should I avoid while taking Dexona 0.5 MG Tablet?

        Ans : Dexona 0.5 MG Tablet can cause sleepiness and dizziness in patients. Hence, it is suggested not to drive after consuming this medicine. THe consumption of alcohol should be avoided as well.

      • Ques : Can the use of Dexona 0.5 MG Tablet lead to weight gain? If yes, how can it be managed?

        Ans : This medicine can increase weight in some individuals. Infact, it is one of the most common side effects. You must make changes in your lifestyle such as exercising regularly and eating a healthy diet in order to manage your weight.

      • Ques : Can the use of Dexona 0.5 MG Tablet affect my sex life?

        Ans : It is very rare of this medicine to affect your sex life. Talk to your doctor if you develop these symptoms after consumption of this medicine.

      • Ques : I am taking Dexona 0.5 MG Tablet for trigeminal neuralgia. For how long do I need to take it?

        Ans : You must take it for a few weeks unless the pain is relieved. In case you want to stop taking it, first consult your doctor.

      • Ques : How can I reduce the side effects of Dexona 0.5 MG Tablet?

        Ans : If the side effects persist for a longer duration, consult a doctor to alter the doses in order to reduce the side effects.

      References

      • Carbamazepine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 27 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/carbamazepine

      • CARBAMAZEPINE- carbamazepine tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2008. [Cited 27 April 2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c13bc0b8-7900-4ef4-98ed-e1315a08d95d

      • Carbamazepine- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 27 April 2019]. Available from:

        https://www.drugbank.ca/drugs/DB00564

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Vishwas Madhav ThakurMD-HRM, AFIH, PGDMLS, MBBS, MD-HMGeneral Physician
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