Duzela M Tablet

Duzela M Tablet is an antidepressant drug that is used in the treatment of depressive disorders and pain disorders. It is a combination of two drugs that are used to relieve neuropathic pain. It functions by protecting the nerve fibres from damage as well as fixing the damaged nerves. Thus, effectively reduces the pain and elevates the mood.

Duzela M Tablet should be taken as prescribed by the doctor at the same time every day to maintain its consistency in the body. It is important to not skip a dose of Duzela M Tablet, however, if missed take the medicine as soon as possible.

The full course of treatment should be finished, additionally, the patient should not stop taking Duzela M Tablet without a doctor’s permission.

Duzela M Tablet may induce side effects in some individuals like erectile dysfunction, headache, constipation, insomnia, nausea, ejaculation disorder, and low sexual desire. However, these side effects usually resolve on their own with time, in case they subside, consult with the doctor immediately.

The doctor may prescribe a small dose initially and then increase it gradually. Ensure to take your doses regularly to get the benefit. If you miss a dose you can take it later, but do not take multiple doses at once to make up for the missed ones. Overdose of Duzela M Tablet can lead to toxic side effects.

While taking Duzela M Tablet, patients should avoid alcohol consumption as it may worsen the side effects. Notify your doctor if you experience any changes in mood, behaviour, suicidal thoughts, worsening of depression.

• Major Depressive Disorder

• Anxiety

• Diabetic Peripheral Neuropathy

• Chronic Musculoskeletal Pain

• Fibromyalgia

• Allergy

• Monoamine oxidase inhibitors

• Nausea

• Sleepiness

• Dry Mouth

• Body Pain

• Joint Pain

• Abnormal Ejaculation

• Loose Stools

• Shaking Of Hands Or Feet

• Heartburn

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 24 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed in 6 to 10 hours.

• Are there any pregnancy warnings?

  This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is known to excreted through the breast milk. It is not recommended for breastfeeding women unless absolutely necessary. However, monitoring of side effects like drowsiness, weight gain is necessary.

• Is It safe with alcohol?

  It is unsafe to consume alcohol with this medicine.

• Is it safe to drive while on this medicine?

  This medicine cause the side effects that affects the alertness of the patients. Thus driving must be avoided while taking it.

• Does this affect kidney function?

  Caution must be taken in patients with severe kidney disease. Adjustment of dose is needed. Kindly consult your doctor before taking it,

• Does this affect liver function?

  This medicine is probably found to be unsafe to be used in patients with liver disease and thus must be avoided. Kindly consult your doctor.

• Missed Dose instructions

  Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

Duzela M Tablet is a serotonin-norepinephrine reuptake inhibitor. It works by inhibiting the reuptake of serotonin and norepinephrine thus increasing its levels in the brain and helps in relieving the symptoms of depression. It weakly inhibits the reuptake of dopamine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

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  Duzela M Tablet may increase the risk of liver injury if taken with alcohol. Avoid consumption of alcohol. Monitoring of liver enzymes is necessary. Any symptoms of abdominal pain, yellow discolouration of skin and eyes should be reported to the doctor.

• Interaction with Lab Test

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  Information not available.

• Interaction with Medicine

  Ciprofloxacin

  Duzela M Tablet is not recommended with ciprofloxacin due to the risk of serious effects like the fast heartbeat, confusion, blurred vision. Inform the doctor if you are receiving these medications. An alternate medicine should be considered based on the clinical condition.

  Aspirin

  Duzela M Tablet may increase the risk of bleeding when taken with other medicines that affect the blood clotting. Any symptoms of blood in stools, nausea, dizziness should be reported to the doctor. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

  Diuretics

  Duzela M Tablet may increase the risk of low blood sodium levels when taken with diuretics. Any symptoms of nausea, dizziness, weakness should be reported to the doctor. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

  Dextromethorphan

  Duzela M Tablet is not recommended with dextromethorphan due to the risk of the fast heartbeat, muscle spasm, tremors. Inform the doctor if you are receiving any cough preparation containing this medicine. An alternate medicine should be considered based on the clinical condition.

• Interaction with Disease

  Diabetes

  Duzela M Tablet should be used with caution in the patients with diabetes mellitus due to the alteration in the blood glucose levels. Monitoring of blood glucose levels is necessary. Any signs and symptoms like increased blood glucose levels, increased urination should be reported to the doctor.

  Glaucoma

  Duzela M Tablet should be used with caution in the patients with glaucoma due to the increase in the fluid pressure in the eye. Inform the doctor if you have any history of eye disorder. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

• Interaction with Food

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  Information not available.

• Ques : Is it safe to drink while taking Duzela M Tablet?

  Ans : It is advised to not drink while taking Duzela M Tablet as it worsens the appearance of side effects.

• Ques : How long does the effect of Duzela M Tablet last in the body?

  Ans : The effect of Duzela M Tablet lasts in the body for approximately 12 hours.

• Ques : Where is Duzela M Tablet approved?

  Ans : Duzela M Tablet is approved in India, USA, and Japan.

• Ques : Is it safe to suddenly stop using Duzela M Tablet?

  Ans : It is not recommended to suddenly stop using Duzela M Tablet as it may induce withdrawal symptoms and increase the risk of adverse effects.

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  https://druginfo.nlm.nih.gov/drugportal/rn/116539-59-4

• Mecobalamin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/methylcobalamin

• Duloxetine - DrugBank [Internet]. Drugbank.ca. 2021 [cited 3 December 2021]. Available from:

  https://go.drugbank.com/drugs/DB00476

• Mecobalamin - DrugBank [Internet]. Drugbank.ca. 2021 [cited 3 December 2021]. Available from:

  https://go.drugbank.com/drugs/DB03614