Zerodol Th 4 Tablet

Zerodol Th 4 Tablet is chiefly known as a pain killer. It is primarily used to treat pain caused due to muscle spasm. This medication is a combination of Aceclofenac and Thiocolchicoside.

These two drug belongs to the class of non-steroidal anti-inflammatory drugs and natural anti-inflammatory glycosides, respectively. The drug combination works together and helps in improving muscle movement and also relieves discomfort and pain associated with the spasm.

This drug works by blocking the effect of cyclooxygenase (COX) enzymes which make chemical prostaglandins at sites of injury or damage causing pain, swelling and inflammation.

The side effects of this drug include nausea, vomiting, diarrhoea, flatulence, constipation, dyspepsia, drowsiness, confusion, etc. You should not be taking this medicine if–

• You are allergic to this drug or other anti-inflammatory painkillers.
• You ever had a problem with stomach or duodenal bleeding.
• You have a heart condition or impaired kidney or liver function.
• You are pregnant or breastfeeding woman.
• You have high blood pressure or blood clotting problems.

Zerodol Th 4 Tablet interacts with medicines like lithium, digoxin, corticosteroids, antihypertensives, etc and certain diseases like asthma, gastrointestinal toxicity. It can be taken with food or after food.

Drinking an adequate amount of water minimises chances of indigestion and stomach irritations. The duration and amount of medicine should be followed as per the doctor’s prescription.

Also Read: Nebasulf Dusting Powder Uses

• Muscle Spasm

• Pain Relief

• Allergy

  Avoid if you have a known allergy to Zerodol Th 4 Tablet or other NSAIDs.

• Asthma

  Zerodol Th 4 Tablet is not recommended if you are diagnosed with asthma.

• Bleeding

  Zerodol Th 4 Tablet is not recommended if you are suffering from any bleeding disorder. It could cause severe swelling and bleeding in the stomach, colon, and anus.

• Abdominal Pain

• Constipation

• Diarrhoea

• Nausea Or Vomiting

• Skin Rash

• Itching

• Sleepiness

• Headache

• How long is the duration of effect?

  Zerodol Th 4 Tablet is excreted in urine and the effect lasts for a duration of 12 to 16 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed in 1.5 to 3 hours after oral administration.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  Zerodol Th 4 Tablet is not recommended for breastfeeding women.

• Is It safe with alcohol?

  The medication is not safe with alcohol. If you experience certain symptoms such as stomach bleeding or ulcers, then you must speak to your doctor immediately.

• Is it safe to drive while on this medicine?

  Yes, you can drive after taking this pill.

• Does this affect kidney function?

  Patients who have impaired kidney function should not take this pill as it can lead to more kidney problems.

• Does this affect liver function?

  Patients who have impaired liver function should not take this pill as it can lead to more liver problems, including liver failure.

Below is the list of medicines, which have the same composition, strength and form as Zerodol Th 4 Tablet , and hence can be used as its substitute.

• Loyfenac-T 100mg/4mg Tablet

  Lloyd Healthcare Pvt Ltd

• Numol Mr 4 Tablet

  Karnataka Antibiotics & Pharmaceuticals Ltd

• Algic Mr 100Mg/4Mg Tablet

  MSN Laboratories

• Aclof-Th4 Tablet

  Neuron Pharma Pvt Ltd

• Thiopace 4Mg Tablet

  Evaxo Pharma

• Rhumacort-Th 4 Tablet

  Galpha Laboratories Ltd

• Ibicox Mr Tablet

  Indian Drugs & Pharmaceuticals Ltd

• Big Nac Mr 100Mg/4Mg Tablet

  Ronyd Healthcare Pvt Ltd

• Neorelax A 4Mg Tablet

  Meyer Organics Pvt Ltd

• Willgo Th 4 Tablet

  Panacea Biotec Ltd

• Missed Dose instructions

  The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

• Are there any overdose instructions?

  A doctor should be contacted immediately if an overdose of Zerodol Th 4 Tablet is suspected. Signs and symptoms of overdose include rashes on the skin, confusion, pain in the chest, blurred vision etc. Immediate medical attention is needed if an overdose is confirmed.

Zerodol Th 4 Tablet is a combination of Aceclofenac and Thiocolchicoside, thus it works via a dual mechanism of action. The former drug, Aceclofenac, belongs to the class of a non-steroidal anti-inflammatory drug that helps relieve pain. Prostaglandins are responsible for pain, inflammation, swelling and fever. It inhibits the action of cyclooxygenase in the brain which is involved in the production of prostaglandins.

The latter constituent, Thiocolchicoside, is a derivative of glucoside, colchicoside that is contained within the Colchicum autumnale plant. It is a type of synthetic sulphur derivative. This medication has a high affinity for g-aminobutyric acid receptors. It activates GABA pathways and acts on the muscular contractures.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  The medication reacts with alcohol violently and can cause serious damage to your health with severe or irreversible side effects.

• Interaction with Medicine

  Yes, it can cause some serious health issues upon interaction with certain medicines. Therefore, it is crucial that you inform your doctor about all the medication you are already taking. Ketoconazole, methotrexate, warfarin, amoxicillin and clavulanic acid are few of the medicines that can cause severe side effects when interacted with Nicip Plus tablet.

• Interaction with Disease

  It can cause or worsen some of the serious conditions related to liver diseases. It is advisable that you do not use the medication if you have any kind of impairment in the liver.

• Interaction with Food

  There is no sufficient information regarding the interaction between the medicine and any specific food.

• Ques : What is Zerodol Th 4 Tablet?

  Ans : Zerodol Th 4 Tablet is a NSAIDs (non-steroidal anti-inflammatory drugs). This medication contains Aceclofenac and Thiocolchicoside as active ingredients in it. This medicine works by blocking the action of cyclooxygenase in the body and reduces swelling and pain. It eases the pain and reduces inflammation.

• Ques : What is the use of Zerodol Th 4 Tablet?

  Ans : This is a medicine used to treat, prevent and control the conditions such as Lumbago, Osteoarthritis, Rheumatoid arthritis and Ankylosing spondylitis. Zerodol th 4 tablet is also can be useful in treating conditions like: Muscles stiffness in the joints, spine and nerve Lumbago Pain caused by non articular rheumatism Ischiadynia Ankylosing spondylitis Periarthritis of scapulohumeral Muscle spasm

• Ques : What are the side effects of Zerodol Th 4 Tablet?

  Ans : Zerodol th 4 tablet medication which has some side effects. Some side effects may or may not occur always but some of them can be rare and serious. In case, any of the side effects appears. Contact your doctor immediately. The side effects of the Zerodol th 4 tablet are mentioned below:

  1. Nausea and vomiting
  2. Diarrhea
  3. Stomach and epigastric pain
  4. Heartburn
  5. Abdominal pain
  6. Dizziness
  7. Allergies
  8. Dyspepsia
  9. Urticaria
  10. Headache
  11. Urge to vomit
  12. Brief loss of consciousness
  13. Enuresis

• Ques : Can the Zerodol Th 4 Tablet be stopped when my pain is relieved?

  Ans : Zerodol TH tablet is a medication can be discontinued after using a specific time duration. It should be continued if your doctor advises you to do so.

• Ques : Can the use of Zerodol Th 4 Tablet cause dizziness?

  Ans : Yes, using Zerodol TH can cause dizziness.

• Ques : Are there any specific contraindications associated with the use of Zerodol Th 4 Tablet?

  Ans : Zerodol TH is contraindicated to patients having stomach ulcers, painkillers, kidney diseases and heart disorders. Patients having high blood pressure should not take this medication.

• Ques : Can Zerodol Th 4 Tablet be taken with Vitamin B-complex?

  Ans : Yes. Zerodol TH and Vitamin B-complex can be taken together.

• Ques : Will Zerodol Th 4 Tablet be more effective if taken in higher doses?

  Ans : No, It is not advised to take higher doses of Zerodol TH. Patient may feel serious side effects after taking higher dose.

• Thiocolchicoside- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/thiocolchicoside

• Thiocolchicoside - DrugBank [Internet]. Drugbank.ca. 2017 [Cited 25 April 2019]. Available from:

  https://www.drugbank.ca/drugs/DB11582

• Aceclofenac- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/aceclofenac