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Vildagliptin

Prescription vs OTC : Prescription by Doctor required

About Vildagliptin

Vildagliptin is an oral medicine prescribed to patients suffering from type 2 diabetes. It is an anti-hyperglycaemic agent of DDP-4 class of drugs. Tests have shown that it helps hyperglycaemia in type 2 diabetes mellitus.

This medication is used to control diabetes; it is not a cure. Other components of treatment plan are important: follow prescribed diet, medication, and exercise regimen. Take exactly as directed; with meal(s) at the same time each day. Do not change dose or discontinue without consulting prescriber.

It is often prescribed with anti-diabetes medications such as metformin. Your doctor will inform you about the dosage and frequency as per your situation. Kindly follow the instruction as prescribed.

People who have liver problem should avoid taking Vildagliptin medicine. Also people with renal impairment or congestive heart failure should inform their healthcare provider before taking the medicine. Vildagliptin is a recently approved drug but no doubt has side effects too.

Common side effects noted during trials were headache, dizziness, constipation, cough, nasopharyngitis and sweating. Some of the studies also reported a feeling of hypertension amongst the patients. Vildagliptin can also lead to weight gain.

Avoid alcohol while taking this medication; could cause severe reaction. Inform prescriber of all other prescription or OTC medications you are taking; do not introduce new medication without consulting prescriber.

Do not take other medication within 2 hours of this medication unless so advised by prescriber. Maintain regular dietary intake and exercise routine and always carry quick source of sugar with you.

You may experience side effects during first weeks of therapy (headache, nausea); consult prescriber if these persist. Report severe or persistent side effects, extended vomiting or flu-like symptoms, skin rash, easy bruising or bleeding, or change in color of urine or stool.

Read more about: Type 1 diabetes

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the uses of Vildagliptin

    • Type 2 Diabetes

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the contraindications of Vildagliptin ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the side effects of Vildagliptin ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    Key highlights of Vildagliptin

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      This medicine may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      This medicine is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      It may cause dizziness. Exercise caution if you have to drive or operate a machinery.

    • Does this affect kidney function?

      Caution should be used in patients with moderate to severe renal impairment or with end-stage renal disease.

    • Does this affect liver function?

      Not advisable in patients with liver disease.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Vildagliptin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    Medicines containing Vildagliptin

    Below is the list of medicines, which contains Vildagliptin as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    How does this medication work?

    This medicine works by blocking dipeptidyl peptidase-4 (DPP-4). Therefore inactivation of GLP-1 by DPP-4 is prevented and GLP-1 is allowed to potentiate the production of insulin in the beta cells. It controls blood glucose by debasing GIP and GLP-1.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

      What are the interactions of Vildagliptin ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        Concomitant use of this medicine must be avoided along with ACE inhibitors, thiazide-like diuretics, thyroid hormones, sulphonylureas, corticosteroids and sympathomimetic drugs.
      • Interaction with Disease

        Precautions must be taken in patients with severe hepatic disorders, type-1 diabetes, dialysis-dependent severe renal disorders and diabetic ketoacidosis.

      FAQs about Vildagliptin

      • Ques : What is Vildagliptin used for?

        Ans : Vildagliptin is used for patients suffering from type 2 diabetes.

      • Ques : Where is Vildagliptin approved?

        Ans : Vildagliptin is approved in India, Micronesia, and Japan.

      • Ques : How is Vildagliptin administered?

        Ans : Vildagliptin is administered orally.

      • Ques : What are the storage indications for Vildagliptin?

        Ans : Vildagliptin should be stored between 20 to 25℃, away from the humid environment and direct heat.

      • Ques : What are the dietary restrictions while taking Vildagliptin?

        Ans : There are no specific dietary restrictions while taking Vildagliptin unless the doctor instructs otherwise.

      • Ques : Is Vildagliptin safe for usage in paediatrics?

        Ans : Vildagliptin is not recommended for usage in paediatrics as its safety and effectiveness are not known.

      • Ques : Is Vildagliptin safe for usage in patients with Arthralgia?

        Ans : Vildagliptin should be used with caution in patients with Arthralgia as it may worsen the patient’s health condition.

      References

      • Vildagliptin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 21 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/vildagliptin

      • Vildagliptin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 21 June 2022].Available from:

        https://go.drugbank.com/drugs/DB04876

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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