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Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 14, 2018

Tolbutamide is a potassium channel blocker and sulphonylurea oral hypoglycemic medicine used in treatment of type 2 diabetes. It is a type of antidiabetic medication used in case proper diet and exercise alone is not sufficient to control and curb diabetes. It stimulates the secretion of natural insulin from pancreas that helps lower the blood sugar levels.

Tolbutamide should not be used if you have a condition of severe allergic reaction to it or any ingredient in it, or have diabetic coma or diabetic ketoacidosis, severe burns or acidiosis. You should also first consult a doctor if you are pregnant, plan on becoming pregnant, breastfeeding, taking any supplements, herbal preparations, or medicines, have history of any hormonal problem, kidney, heart, thyroid or liver problem, or have stomach paralysis, blockage, alcohol addiction, have any medical condition or poor nutrition.

The common side effects of Tolbutamide are heartburn, nausea and a feeling of stomach fullness. Other serious side effects include severe allergic reactions like itching, swelling of lips, throat, tongue, mouth, difficult breathing or rashes. You should see a doctor as soon as possible if you encounter any of these.

Tolbutamide is taken by mouth with food. It is recommended that you take it once every day on a regular basis as per the dosage prescribed by the doctor.

type diabetes

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Diabetologist before using this medicine.

  • Type 2 Diabetes

  • Is It safe with alcohol?

  • Are there any pregnancy warnings?

    Rastinon 500mg tablet may be unsafe to use during pregnancy.
    Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Rastinon 500mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    Vision may be affected with this. Exercise caution if you have to drive or operate a machinery.
  • Does this affect kidney function?

    Should be used cautiously in patients with an underlying kidney disease. Please consult your doctor.
  • Does this affect liver function?

    Should be used cautiously in patients with an underlying liver disease. Please consult your doctor.
  • Are there any missed dose instructions?

    You should skip a dose of Tolbutamide, if a meal is skipped and add a dose of medicine if you eat an extra meal.

Below is the list of medicines, which contains Tolbutamide as ingredient

Tolbutamide lower the blood glucose within patients. It directly stimulates release of the insulin from the functioning of beta cells of the pancreatic islet tissue. It involves a method comprising sulfonylurea receptor acting on beta cell.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Medicine

    Decmax 4Mg Tablet

    Pericort 4Mg Tablet

Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Tolbutamide
What are the uses of Tolbutamide
What are the side effects of Tolbutamide ?
Key highlights of Tolbutamide
What are the dosage instructions?
Medicines containing Tolbutamide
How does this medication work?
What are the interactions of Tolbutamide ?