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Promal Tablet

Manufacturer: Astrum Healthcare Pvt Ltd
Medicine composition: Proguanil
Prescription vs.OTC: Prescription by Doctor required

Promal Tablet is used in combination with atovaquone, for the prevention and treatment of malaria. It is administered orally, and is available in the form of tablets of two types – one for adults and one for children. The dosage is different for the two. This medicine is mostly used to combat the type of malaria known as malignant malaria, the causative organism of which is a protozoan known as Plasmodium falciparum. It is mainly used in regions where a resistance to chloroquine has been widely reported.

The dose should be taken daily, along with food or milk. In case you face difficulty in swallowing, you may crush the tablet and mix it with condensed milk. In case of vomiting within an hour of taking the dose, the dose should be repeated.

The following side effects have been observed in some cases: seizures, hallucinations, anaphylaxis, urticaria, hepatitis, liver failure, sensitivity to sunlight and rashes. Do not take this medicine and Rifampin or Rifambutin simultaneously. Vomiting and nausea have been observed to occur in most patients with regularity. If severe or persistent vomiting or diarrhea occurs, it is highly recommended that the patient be given alternative anti-malarial therapy to treat their medical condition.

In addition to its intended effect, Promal Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Flushing (sense of warmth in the face
neck and trunk)
Gastric intolerance
Loss of appetite
Mouth ulcer
Stomatitis (Inflammation of the mouth)
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Laveran tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
There is no interaction between driving and consuming this drug. So dose alteration is not needed.
Does this affect kidney function?
Caution should be used in patients with renal impairment.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
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Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

What are the symptoms of malaria. I don't have till any medicine tell me name of medicine also.

M.D. Consultant Pathologist, CCEBDM Diabetes, PGDS Sexology USA, CCMTD Thyroid, ACDMC Heart Disease, CCMH Hypertension, ECG
Sexologist, Sri Ganganagar
Common symptoms of malaria include: shaking chills that can range from moderate to severe. High fever. Profuse sweating. Headache. Nausea. Vomiting. Abdominal pain. Diarrhea. Malarone, which is a combination of two antimalarial medicines (atovaquone and proguanil). Malarone is taken to treat malaria caused by chloroquine-resistant P. Falciparum. Quinine plus an antibiotic such as clindamycin, doxycycline, or tetracycline for most P. Falciparum infections.

Popular Health Tips

Malaria - 10 Signs You Must Know!

Sexologist, Jaipur
Malaria - 10 Signs You Must Know!

Malaria refers to the disease transmitted through the bite of an infected mosquito. The primary agent of transmission of this disease is the ‘Anopheles’ mosquito. This particular breed of mosquito carries the species causing organism, a parasitic protozoan, known as ‘Plasmodium species’.

The parasite, upon entering the bloodstream, attaches itself to the liver. It is at this location that the parasite matures and after a few days begins to infect the red blood cells that are secreted by the liver. The red blood cells that are infected tend to explode in about forty eight to seventy two hours due to the rapid multiplication of parasites inside them. The subtropical regions and regions that exist in a broad band around the equator are known to be the hotspots of species.


Upon being infected, the symptoms and signs show up within 10 days to 4 weeks. Some of the general symptoms include:

  1. Nausea

  2. High fever

  3. Headache

  4. Extreme sweating

  5. Moderate to severe chills

  6. Vomiting

  7. Anaemia

  8. Diarrhoea

  9. Pain in muscles

  10. Blood in stools

In some cases, malaria can lead to further severe complications, such as:

  1. Kidney, spleen or liver failure

  2. Cerebral malaria (swollen blood vessels in the brain)

  3. Low blood sugar

  4. Pulmonary oedema (fluid accumulation in the lungs which causes breathing difficulties)

The medications administered for malaria depend on factors such as:

  1. Severity of the infection

  2. Physical conditions such as allergies, pregnancy and other health problems,

  3. Age

Some of the most common medicines used to address malaria include:

  1. Chloroquine

  2. Malarone

  3. Doxycycline

  4. Quinine sulphate

  5. Mefloquine

  6. Hydroxychloroquine

  7. A mix of Proguanil and Atovaquone 

    If you wish to discuss about any specific problem, you can consult a general physician.

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