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Predmet 8 MG Tablet

Manufacturer: Sun Pharma Laboratories Ltd
Medicine composition: Methyl Prednisolone
Prescription vs.OTC: Prescription by Doctor not required

Predmet 8 MG Tablet is a steroid, which prevents the release of certain chemicals in the body that result in inflammation. The drug is quite effective in the treatment of a number of inflammatory health problems such as gland disorders, lupus, arthritis, psoriasis as well as ulcerative colitis. It also treats various other inflammatory conditions of the lungs, skin, eyes, blood cells, stomach and nervous system of the body.

Because the steroid is strong it can lead to a number of side effects which gradually disappear as the body adjusts to the medicine. Some of these side effects are weakness and slight muscle pain, headache, bloating and discomfort of the stomach. Make sure to contact your doctor if you experience the following-

  • Tunnel or blurred vision along with eye pain
  • problems with breathing
  • behavioral changes, mood swing and depression
  • pain in the arms back or leg
  • convulsions
  • Before you start the medicine the doctor needs to ensure if Predmet 8 MG Tablet is safe. Thus make sure to provide him a detailed history of your allergies, overall fitness and existing health problems. Inform him if you suffer from problems like hypertension, heart disease, kidney or liver issues, tuberculosis, pinworms, thyroid disorders, mental illness, epilepsy or cataracts. Depending on your health the doctor will then adjust the dosage of Predmet 8 MG Tablet.

    The dosage of Predmet 8 MG Tablet for adults may vary from 4mg to 48mg daily. In case of children dosage is decided depending upon the health of the patient and condition that is being treated.

    Certain precautions should also be taken to prevent side effects from aggravating. For instance avoid grapefruit juice consumption. it is also advised that ‘live’ vaccines should not be taken when on this drug. Patients taking Predmet 8 MG Tablet can easily catch infections. Thus they should also avoid interacting with sick family members or friends.

Acute Gout

Predmet 8 MG Tablet is used in the treatment of Gout which is a type of joint inflammation. Sudden pain at night time and redness of the joints are few symptoms of Gout.
Predmet 8 MG Tablet is used in the treatment of Psoriasis which is a type of skin disease. Itchy or sore patches and red skin are few symptoms of Psoriasis.
Predmet 8 MG Tablet is used in the treatment of Nephrotic syndrome which is a type of kidney disease. Swelling of face, skin rash are few symptoms of this condition.
Predmet 8 MG Tablet is used in the treatment of Rheumatoid Arthritis (symptoms include swelling, pain, and stiffness of joints).
Predmet 8 MG Tablet is used in the treatment of Asthma which is an inflammation of the airways. Wheezing, cough and difficulty in breathing are few symptoms of Asthma.
Avoid taking this medicine if you are allergic to it or any other glucocorticoids.
Avoid taking this medicine in patients suffering from systemic fungal infections.

Idiopathic thrombocytopenic purpura

Intramuscular injection of Predmet 8 MG Tablet is not recommended in the patients suffering from this condition.
In addition to its intended effect, Predmet 8 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Aggression or anger

Moderate Less Common

Decreased urine output

Moderate Less Common


Moderate Less Common


Moderate Less Common

Difficulty in breathing

Moderate Less Common

Change in mood

Moderate Less Common

Increased appetite

Moderate Less Common

How long is the duration of effect?

The effect of this medicine lasts for a duration of 30-36 hours after an oral dose and 1-4 weeks after an intramuscular injection.

What is the onset of action?

The peak effect of this medicine is observed within 30 minutes of an intravenous injection.

Are there any pregnancy warnings?

This medicine is recommended for pregnant women only if clearly needed and if no other safer alternative is available.

Is it habit forming?

No habit forming tendencies were reported.

Are there any breast-feeding warnings?

This medicine is known to excreted through breast milk in small amounts. Use this medicine only if clearly needed when no other safer alternative is available.
Below is the list of medicines, which have the same composition, strength and form as Predmet 8 MG Tablet , and hence can be used as its substitute.
Micro Labs Ltd
Lupin Ltd
Intas Pharmaceuticals Ltd
Sun Pharma Laboratories Ltd
Indswift Laboratories Ltd

Missed Dose instructions

The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

Overdose instructions

Seek emergency medical treatment or contact the doctor in case of an overdose.
Predmet 8 MG Tablet belongs to Glucocorticoids class of drugs. It works by binding to the receptor and inhibits the release of inflammatory substances thus helps in the treatment of inflammation or allergic disorders.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Gastro-intestinal bleeding

Predmet 8 MG Tablet is used with caution in the patients with gastrointestinal diseases. The risk of bleeding is more when taken for a long duration of time. Dose adjustments are to be made based on the clinical condition.


Predmet 8 MG Tablet is used with caution in the patients with diabetes as it increases the blood glucose levels. Regular monitoring of blood glucose levels is necessary. A suitable antidiabetic agent is prescribed based on the clinical condition.

Interaction with Alcohol


Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Lab Test


Information not available.

Interaction with Food

Grapefruit juice

Consumption of grapefruit juice is not recommended when you are taking Predmet 8 MG Tablet. Inform the doctor if you experience any undesired effects.

Interaction with Medicine

Ethinyl Estradiol

Use with caution as this combination will increase the concentration of Predmet 8 MG Tablet. Inform the doctor if you are taking either of the medicines. Consider an alternative medicine or dose adjustments after consulting your doctor.

Azole antifungal agents

Use of ketoconazole and itraconazole should be avoided as these medicines may increase the concentration of Predmet 8 MG Tablet in the body which may cause swelling, high blood glucose, weight gain, and growth abnormalities in the children. Dose adjustments or an alternative medicine should be considered based on the clinical condition.


Use with caution as this combination will decrease the concentration of Antihypertensives. This interaction is more likely to occur if Predmet 8 MG Tablet is taken for more than a week. Inform the doctor if you are taking either of the medicines. Consider an alternative medicine or dose adjustments after consulting your doctor.

Nonsteroidal anti-inflammatory drugs

Use with caution as this combination will increase the risk of gastrointestinal bleeding. Inform the doctor if you are taking either of the medicines. Consider taking alternative medicine after consulting your doctor.

Ques: What is Predmet 8 MG Tablet?

Ans: Predmet 8 MG Tablet is a medication which has Methylprednisolone as an active element present in it. This medicine performs its action by increasing the level of corticosteroid and controls inflammation. Predmet 8 MG Tablet is used to treat conditions such as Acute Gout, Psoriasis, Nephrotic syndrome, Rheumatoid Arthritis, Asthma, etc.

Ques: What are the uses of Predmet 8 MG Tablet?

Ans: Predmet 8 MG Tablet is a medication, which is used for the treatment and prevention from conditions such as Acute Gout, Psoriasis, Nephrotic syndrome, Rheumatoid Arthritis, Asthma, Osteoarthritis, Bursitis, Lichen simplex chronicus, Lichen Planus, Keloids, Granuloma annulare, and Multiple sclerosis. Apart from these, it can also be used to treat conditions like Allergic rhinitis, Tendonitis, Synovitis, Dermatitis, and Eczema. The patient should inform the doctor about any ongoing medications and treatment before using Predmet 8 MG Tablet to avoid undesirable effects.

Ques: What are the Side Effects of Predmet 8 MG Tablet?

Ans: Predmet 8 MG Tablet is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of Predmet 8 MG Tablet which are as follows: Aggression or anger, Decreased urine output, Dizziness, Headache, Difficulty in breathing, Change in mood, and Increased appetite. It is a list of possible side-effects which may occur due to the constituting ingredients of Predmet 8 MG Tablet.

Ques: What are the instructions for storage and disposal Predmet 8 MG Tablet?

Ans: Predmet 8 MG Tablet should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects. It is a prescribed medication.
What are you using Predmet 8 MG Tablet for?
rheumatic disorder
allergic disorders
skin disorders
severe allergic reaction
eye disorders
How much was the improvement?
How long did it take before seeing improvement?
Within a day
More than 2 days
Within 6 hours
Within 2 hours
Within 2 days
How frequently did you take this medicine?
Once a day
Twice a day
Thrice a day
Not taking on daily level
How did you take this medicine?
With Food
With or without food
Empty stomach
What were the side effects of this medicine?
Bone degradation
Muscle disorders
Increased glucose level
Increased blood pressure
Increased risk of infection
accumulation of body fat
Skin scar
Increased glucose level in blood
Electrolyte imbalance
No Side Effects
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I'm 32 years old I'm unable smell anything from past 4 year I used to take a tablet of predmet 16 mg and still there is no recovery please suggest me.

MBBS Bachelor of Medicine & Bachelor of Surgery, Diploma In Otorhinolaryngology (DLO), DNB - ENT, Allergy Testing
ENT Specialist, Gurgaon
I'm 32 years old I'm unable smell anything from past 4 year I used to take a tablet of predmet 16 mg and still there ...
If you have anosmia or loss of smell, we should get a CT Scan of your sinuses to assess why you are unable to smell. A lot of times a physical obstruction is identified which can be surgically corrected. I would not recommend taking oral steroids without prescription. They are harmful and have many side effects. Let your doctor decide the diagnosis and prescribe a cure. By taking medicine form google is dangerous and has serious side effects.
2 people found this helpful

Hi Doctor! My MOM is Diabetic and has suffered with tuberculosis pericardial effusion and has undergone pericardial tapping process 9 times in 5 different hospitals. She has completed the course (R Cinex, Moxif 400 Mg, Colchicine, Predmet, Pregaba-M, as suggested by the doctors from 26/01/2015 to 27/07/2016. She used to have some pain left side of chest and back side of left shoulder after the surgery Pericardiosynthesis. Doctor's comforted her by saying the pain slowly gets reduced but will take time, but from last 20 days she is getting trouble regularly with some pain in left side of chest and shoulder. We consulted a chest physician and found out there still some fluid visible in the X-ray. Doctor enquired about symptoms like Cough, Breathing Problem, Digestion etc. But she is not experiencing all those symptoms but has some pain and is comfortable with daily activities like walking, household work. Doctor told us there's no need to worry if there are no symptoms, but Me and my mom are not happy with this suggestion as she is experiencing the pain daily sometimes low and sometimes medium pain. She wants to get rid of that pain completely as she is suffering since 2 years and she is fed up with it. Kindly let me know how to relieve her from this pain, I will send the latest x-ray if needed. Thank You.

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
If your blood sugar levels are normal do not worry because TB microbes remain dormant and flourish in favourable conditions. Tab tulsi 1 twice a day tab yastimadhu 1 twice a day 1 panch tikta gruth gugule twice a day mixture of (arjun+puskarmul+amalki+kutki+patol+nimba+draksha+haldi) each in equal quantity daily 1/2 tsf twice a day with water apply til taila +saindhv luke warm at back of chest and gently massage then have bath with warm water for fomentation be in fresh air in morning and sun bath before 10 am for 15 mins.
1 person found this helpful

I am suffering from knee pain from 6mon .Dr prescribed tab predmet 8 mg. Daily 1 I am taking. If I stop for 3 days again severe knee pain. It should be taken life long or when to stop. Sir what is the other option rather then steroid. Please help.

DHMS (Hons.)
Homeopath, Patna
I am suffering from knee pain from 6mon .Dr prescribed tab predmet 8 mg. Daily 1 I am taking. If I stop for 3 days ag...
Hello, Lybrate user, You need to go for physiotherapy along with medication, please. Tk, homoeopathic medicine:@ Colchicum 1000-6 pills twice a wk. Avoid, jerk, cold intake, please. Tk, care.
1 person found this helpful

Popular Health Tips

Alzheimer's Disease - Can Surgery Help You Treat It?

MBBS, MD - Radiology, DNB (Radiology), DM (Diagnostic & Interventional Neuroradiology), CCST (UK)
Neurosurgeon, Kolkata
Alzheimer's Disease - Can Surgery Help You Treat It?

In recent times, the advancement of medical science has substantially contributed in comprehending the Alzheimer’s disease. Unfortunately, the number of individuals suffering from the disease is expected to rise in the next ten years which pose a threat to the allocation of health care resources and public health. Alzheimer’s disease is thought to be a complex disease which influences a person’s behavior as well as cognition through numerous mechanisms.

Can surgery be deemed as a treatment for Alzheimer’s disease?
The surgery is a multicenter clinical trial which is making a new direction in clinical research. It is devised to halt or slow down the problems caused by the disease which gradually erases a lifetime of memories in elderly patients. Though there is no cure for Alzheimer’s disease, it has been found that low-voltage electric charges delivered right at the brain. Only the symptomatic therapies for Alzheimer’s disease are provided which do not have any effect on the evolution of the disease. The standard medical treatments for Alzheimer’s disease include cholinesterase inhibitors along with a partial N-methyl D-aspartate antagonist. In most cases of mild to moderate symptoms of this disease, a combination of treatments is used according to the clinical history, age and condition of the patient.

Mental activity supporting cognition
Many patients having normal cognition or mild impairment have a fear that they may develop AD. Many experts are of the opinion that mentally challenging activities including brain teasers and crossword puzzles can be helpful in reducing the risks in such patients. Clinical trials are under the way for determining whether or not these types of activities have any substantial effect on halting the progression of AD.

Treating AD in its moderate to the severe stage
Numerous studies have shown that blockade of NMDA receptors by memantine can be used safely in combination with ChEls. This combination has been shown to delay the institutionalization in patients with Alzheimer’s disease.

Treating secondary symptoms
A variety of behavioral as well as pharmacologic interventions can help in overcoming the clinical manifestations of the disease. These include anxiety, psychotic behavior, depression and agitation among others. The effectiveness of this disease can range from modest to excellent. No particular agent or dose of it can be unanimously accepted to be the sole treatment option for the wide range of clinical issues. Moreover, in the recent time, the FDA has not accepted any psychotropic agent for treating AD.

Along with these treatment options, there are behavioral interventions that can range from patient-centred approaches to caregiver training for helping manage the cognitive and behavioral manifestations of Alzheimer’s disease. Last but not the least, it is very crucial to point out the significance of treatment in the early stages of AD in order to cure it better. In case you have a concern or query you can always consult an expert & get answers to your questions!

2944 people found this helpful

Who Is At Risk Of Osteoporosis?

DNB (Orthopedics), MS - Orthopaedics
Orthopedist, Visakhapatnam
Who Is At Risk Of Osteoporosis?

Osteoporosis is a condition which usually results due to a decrease in bone density. In this condition, the bones become weak and brittle. Fractures are a common result of osteoporosis. Usually, symptoms or signs do not show up until the condition progresses to its advanced stages.

Since osteoporosis is usually irreversible and incurable, preventing the fractures is considered to be extremely important.

Who is at risk of osteoporosis?
All men and women have some risk of developing 'thinning' of the bones (osteoporosis) as they become older, particularly over the age of 60. As mentioned above, women are more at risk than men. The following situations may also lead to excessive bone loss and so increase your risk of developing osteoporosis. If you:

  1. Are a woman who had the menopause before 45 years of age
  2. Have already had a bone fracture after a minor fall or bump
  3. Have a strong family history of osteoporosis.
  4. Have a body mass index (BMI) of 19 or less (that is, you are very underweight)
  5. Have irregular periods
  6. Have taken, or are taking, a steroid medicine (such as prednisolone) for three months or more
  7. Are a smoker
  8. Have an alcohol intake of more than four units per day
  9. Lack calcium and/or vitamin D (due to a poor diet and/or little exposure to sunlight).
  10. Are mostly inactive

Ways To Treat Osteporosis

Osteoporosis in women can be treated using Hormone Replacement Therapy (HRT). The therapy makes use of either a combination of progestin and oestrogen or simply, oestrogen. However, it is possible that certain combinations have side-effects that might give rise to other medical conditions. Therefore, proper consultation with an orthopedist is an essential pre-requisite so that the condition of osteoporosis as well the side effects may be addressed before proceeding with Hormone Replacement Therapy.

There are a number of medications that can be used which have long-term effects on osteoporosis. However, the schedule for intake of these medicines should be followed diligently. Failing to adhere to the schedule could lead to serious complications. For example, the intake of Risedronate medications (prevent bone loss) should be scheduled once every month, failing which can cause ulcers in the food pipe. Raloxifene has effects which are similar to oestrogen but does not exhibit any serious side effects. Teriparatide can be used to treat osteoporosis in people who have a high risk of suffering from bone fractures.

Don't rely entirely on medication as the only treatment for your osteoporosis. These practices also are important:

  1. Exercise. Weight-bearing physical activity and exercises that improve balance and posture can strengthen bones and reduce the chance of a fracture. The more active and fit you are as you age, the less likely you are to fall and break a bone.
  2. Good nutrition. Eat a healthy diet and make certain that you're getting enough calcium and vitamin D. Being underweight or losing a lot of weight unintentionally is associated with poorer bone health and a higher risk of fracture — even if you're taking a bisphosphonate.
  3. Quit smoking. Smoking cigarettes speed up bone loss.
  4. Limit alcohol. If you choose to drink alcohol, do so in moderation. For healthy adults, that means up to one drink a day for women of all ages and men older than age 65, and up to two drinks a day for men age 65 and younger.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2659 people found this helpful

Seizures - 3 Ways It Can Be Treated!

MCh - Neurosurgery, MS-General Surgery, MBBS
Neurosurgeon, Delhi
Seizures - 3 Ways It Can Be Treated!

The primary aim of the treatment in patients suffering from seizure is leasing a seizure-free life without giving way to any adverse effects. This goal can be accomplished in over 60 percent people with the help of anticonvulsants. Some patients also experience adverse effects since they suffer from a seizure which is refractory to medical therapy. Here are some of the common treatment options for seizures:

  1. Monotherapy: Sometimes, monotherapy is given as it reduces the chance of all sorts of adverse effects and even avoids drug interactions. Moreover, this type of treatment approach is much less expensive than polytherapy since many older generation of the anticonvulsant agent comprises of hepatic enzyme which is responsible for reducing the serum level of the concomitant drug which leads to an increase in the dosage level of such medicines.
  2. Social And vocational rehabilitation: People suffering from problems in psychosocial adjustments after the diagnosis may also need social and vocational rehabilitation. Many physicians do not pay enough attention to the consequences that an epilepsy diagnosis may leave on the patient. For instance, people with epilepsy may have a fear of experiencing next attack of seizure and they may be unable to work at heights or drive.
  3. Consulting an expert: It is important to refer patients with intractable spells to epileptologist or neurologist for subsequent workup. A neurosurgical consultation may also be needed when the patient has to be treated surgically.

Importance of anticonvulsant therapy

Patients who have had already suffered from recurrent attacks of unprovoked seizure may need treatment with an anticonvulsant. This treatment is not recommended until the person has risk factors for suffering from the problem yet again. The primary means of treating seizure is anticonvulsant therapy where the most suitable drug is chosen based on accurate diagnosis of the syndrome as a response to specific anticonvulsants may vary from one patient to another. The difference in response may reflect the various pathophysiologic mechanisms in different types of seizures.

Types of anticonvulsant therapy
Some of the anticonvulsant therapy medication may have multiple action mechanism while some have an only single mechanism of action. Some of the most common variants of the therapy include:

  1. Neuronal potassium channel referred to as KCNQ opener
  2. Blockers of unique binding sites such as perampanel, gabapentin, and levetiracetam
  3. H-current modulators such as lamotrigine and gabapentin
  4. Carbonic anhydrase inhibitors such as zonisamide and topiramate
  5. Alpha-amino 3-hydroxy 5-methyl 4-isoxazole propionic acid receptor blockers like topiramate and perampanel.
  6. N and L-calcium channel blockers like zonisamide, valproate, topiramate, and lamotrigine

Even though there are so many types of drugs available, all of them cannot be used for the treatment of seizures. Doctors would evaluate the condition thoroughly before prescribing a medication that can be helpful in reducing the severity of the condition.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2745 people found this helpful

Parkinsonism - Factors That Can Lead To It!

MD - Ayurveda, CIY, Guru Shishya parampara, BAMS
Ayurveda, Gurgaon
Parkinsonism - Factors That Can Lead To It!

Parkinsonism is often mistaken for Parkinson's Disease. Though similar in quite a few aspects, yet Parkinsonism is not the same as Parkinson's Disease. Parkinsonism is a medical condition whereby the affected individual exhibits some symptoms identical to those observed in the case of a Parkinson's disease.

Factors that lead to Parkinsonism
Parkinsonism can result from a host of factors and health condition such as

  1. Increased and repeated exposure to toxic gases and substances, namely organic solvents, cyanide, manganese, or carbon monoxide.
  2. People suffering from the repeated head injury (as in the case of boxing or wrestling).
  3. The medications used in the treatment of psychiatric problems (antipsychotic medicines) or those used in treating nausea (Prochlorperazine or even Metoclopramide). Some of the antipsychotic drugs have the potential to interfere (block) with the activity of the neurotransmitter Dopamine resulting in parkinsonism.
  4. The use of MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine), especially the oxidized product MPP+ (1-methyl-4-Phenylpyridinium) can wreck havoc resulting in parkinsonism and the associated symptoms.

Some of the medical conditions that can contribute towards Parkinsonism include

  1. Viral Encephalitis (resulting in acute brain inflammation).
  2. Alzheimer's Disease (a progressive neurodegenerative disorder that triggers cognitive and behavioral problems often accompanied with dementia).
  3. Multiple system atrophy (a progressive neurodegenerative disorder resulting in dysfunctioning of the autonomic nervous system and the voluntary movements).
  4. Progressive supranuclear palsy or Steele-Richardson-Olszewski syndrome (a rare disorder of the brain that interferes with the balancing, walking, and the eye movements of the affected person.
  5. Stroke or a brain tumor.
  6. Lewy body dementia (a condition triggered by the unusual accumulation of alpha-synuclein protein in the brain with the person exhibiting symptoms associated with both Alzheimer's disease and Parkinson's disease).
  7. Wilson Disease (an autosomal recessive condition whereby copper starts accumulating in the vital organs including the liver and the brain).

In patients with parkinsonism,

  1. The muscles appear stiff. A person experiences a resting tremor (tremor that mainly affects one hand even when the muscles are relaxed), along with difficulty while walking or balancing their body. (These symptoms are also characteristic of a Parkinson's disease).
  2. Further, there may be early signs of dementia (loss of memory or forgetfulness). There may be Agnosia, Aphasia, or Apraxia
  3. Constipation, a dip in the blood pressure, difficulties in eating or swallowing of food.
  4. Hallucinations and loss of judgment (such as failing to locate the kitchen or bathroom at home).
  5. Unusual eye movements.

Ayurvedic Treatment
According to Ayurveda, Parkinsonism is a manifestation of the vitiation of the Vata Dosha (Wind energy) that takes place in the cranial nerves. Thus, corrective measures are followed to restore the balance between the Vata, Kapha, and Pitta Dosha.

  1. Panchakarma can bring about a visible improvement in patients with Parkinsonism. Oil massages using Ashwagandha and Bala can work wonders.
  2. Brahmi is another wonder herb used to treat Parkinsonism.
  3. Meditation, exercise (light to moderate), yoga can be helpful in the case of Parkinsonism.
  4. Try and make the diet as nutritious and healthy as possible.
  5. A Warm Ayurvedic Oil Application is very effective in relieving these kinds of aches and pain if done on regular basis.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4445 people found this helpful

Giant Hives: What Are The Causes Behind?

MBBS, MD - Dermatology , Venereology & Leprosy, Cosmetologist
Dermatologist, Chandigarh
Giant Hives: What Are The Causes Behind?

Allergic reactions are the body’s way of responding to foreign substances. The body recognizes these substances (be it food, pollens, insect bites, etc.) as antigens and produces antibodies. These antibodies can cause various reactions depending on the severity of the allergen, be it skin rash, hives, or angioedema. In severe cases, there could be swelling of the tongue and the respiratory tract, leading to choking of the airways.

Literally, angioedema means swelling of the blood vessels. These are located in the underlying layers of the skin and their swelling can lead to formation of giant hives, which can be extremely itchy, reddish, and oval or circular in shape. The affected area is usually warm and painful to touch.


Angioedema is caused due to the following:

  1. Food allergies including eggs, peanuts, shellfish, milk, tree nuts, chocolates, etc.

  2. Insect bites or stings

  3. Pollen, latex, animal dander, poison ivy, and other common allergens

  4. Medications like aspirin, penicillin, ibuprofen, and some blood pressure medicines

  5. In response to blood transfusions

  6. Auto-immune disorders like lupus

  7. Conditions like leukemia and thyroid disorders

  8. Infections like hepatitis, cytomegalovirus infections, Epstein-Barr infections, etc.

  9. Weather conditions like extremes of cold, heat, or pressure

  10. Extreme emotional stress

  11. Genetic angioedema, passed on from parents to children, which could last forever

While hives usually develop without any warning, the following condition puts a person at risk of developing angioedema.

  1. Predisposition to allergic reactions (highly active immune system)

  2. Previous history of allergies

  3. Genetic history of allergies or angioedema

Most angioedema cases are limited to the skin and hives, but there could be severe cases leading to respiratory distress.


If it is the first instance of hives, the doctor would ask detailed questions about similar occurrence in the past. They would also check if there are similar hives on other parts of the body like the back, which you may have missed. If required, this examination is followed by allergy testing and blood testing. The allergy testing will help identify if you are allergic to some of the common things which cause allergy. The blood test will look for your eosinophil count, which is usually high in people prone to allergies. C1 esterase inhibitor test and complement particles also can be checked, if there is suspicion of genetic angioedema.


This would depend on the severity of symptoms

  1. In case of angioedema, admission in hospital may be needed.
  2. Tracheostomy may also become essential to save patients life.
  3. Vigorous therapy with intravenous medications like steroid, antihistamines and others may be needed.
  4. Under medical treatment, antihistamines like cetirizine and loratadine are prescribed. However, severe cases may require steroids like prednisolone.


Once you know what caused it, avoid exposure to these substances and further attacks can be prevented. If you wish to discuss about any specific problem, you can consult a Dermatologist.

2609 people found this helpful
Table of Content
About Predmet 8 MG Tablet
When is Predmet 8 MG Tablet prescribed?
What are the contraindications of Predmet 8 MG Tablet ?
What are the side effects of Predmet 8 MG Tablet ?
Key highlights of Predmet 8 MG Tablet
What are the substitutes for Predmet 8 MG Tablet ?
What are the dosage instructions?
How does medicine works?
What are the interactions for Predmet 8 MG Tablet ?
Predmet 8 MG Tablet Frequently Asked Questions (FAQs):