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Nikoran 5Mg Tablet

Manufacturer: Torrent Pharmaceuticals Ltd
Medicine composition: Nicorandil
Prescription vs.OTC: Prescription by Doctor not required
Last Updated: August 17, 2019

This medication is a vasodilatory drug. It treats angina chest pain. Also, it widens blood vessels thus increasing the blood and oxygen flow to the heart. This medicine is used to treat other heart conditions also.

The dosage should be prescribed by your doctor based on your medical history and current condition. The usual dose in adults is about 10 mg twice a day which may be increased to 20 mg depending on your response. On using this medication you may experience side effects such as

  • Rapid or Irregular heartbeat
  • Swelling
  • Darkening of urine
  • Headache
  • Fatigue

The most well-known utilization of this medication is

  • Hypotension

  • Hypotension

Here are some possible side effects of this medication

  • Is It safe with alcohol?

    Interaction with alcohol is unknown. Please consult your doctor.
  • Are there any pregnancy warnings?

    This medicine is extremely unsafe to be used during pregnancy. Studies carried out on humans and animals have shown significant adverse effects on the fetus. Doctor consultation is recommended in such cases.
  • Are there any breast-feeding warnings?

    This medication is probably unsafe to use during breastfeeding. Please consult your doctor.
  • Does this affect kidney function?

    There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.
  • Does this affect liver function?

    There is no data available. Please consult doctor before consuming the drug.

Below is the list of medicines, which have the same composition, strength and form as Nikoran 5Mg Tablet , and hence can be used as its substitute.

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  • Are there any missed dose instructions?

    If you miss a dose of Nicorandil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.
  • Are there any overdose instructions?

    In case of overdose, consult your doctor.

This medication works following a dual mechanism. Firstly, it activates the ATP sensitive potassium channel, leading to vascular smooth muscle hyperpolarization. Secondly, it triggers guanylate cyclase to enhance the production of cyclic GMP, thereby activating protein kinase G. Therefore, GTPase RhoA is inhibited and Rho-kinase activity is decreased. As a result, the myosin phosphate activity is accelerated and the calcium sensitivity of the smooth muscle is reduced. Owing to its nitrate property, nicorandil works as a vasodilator.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Disease

    This medication interacts with Gastrointestinal Disorders.
  • Interaction with Medicine

    This medication interacts with Corticosteroids, Riociguat, NSAIDs, Phosphodiesterase 5 (PDE) inhibitors, and Vasodilators.

Ques: What is Nikoran 5Mg Tablet?

Ans: This is a medication which has Nicorandil as an active element present. It performs its action by calming the blood vessels of the heart and increasing the supply of blood and oxygen to the heart and decreases pain.

Ques: What are the uses of Nikoran 5Mg Tablet?

Ans: This is a medication, which is used for the treatment and prevention from conditions such as Angina pectoris and Acute coronary syndrome.

Ques: What are the Side Effects of Nikoran 5Mg Tablet?

Ans: This is a medication which has some commonly reported side effects such as Hypersensitivity, Yellowing of skin and eyes, Increase in the potassium levels, Watery eyes, Gastric Ulcer, Hypotension, Nausea and vomiting, etc.

Ques: What are the instructions for storage and disposal Nikoran 5Mg Tablet?

Ans: This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Nikoran 5Mg Tablet
What are the uses of Nikoran 5Mg Tablet
What are the contraindications of Nikoran 5Mg Tablet ?
What are the side effects of Nikoran 5Mg Tablet ?
Key highlights of Nikoran 5Mg Tablet
What are the substitutes for Nikoran 5Mg Tablet ?
What are the dosage instructions?
How does this medication work?
What are the interactions of Nikoran 5Mg Tablet ?
FAQs about Nikoran 5Mg Tablet