Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 20, 2021

Neomycin is used orally to prepare GI tract for surgery. When applied topically, it is used to treat minor skin infections. The primary use of this medicine is to treat diarrhoea caused by E. coli. It is also used as an adjunct in the treatment of hepatic encephalopathy.

Used to reduce bacteria in the intestines, Neomycin is an aminoglycoside antibiotic. It works by destroying sensitive bacteria by cutting off the production of certain proteins needed for them to survive. Keeping this in mind, it is used to stave off the risk of infections during intestinal surgeries. It can also be used along with a certain diet to treat hepatic encephalopathy.

Neomycin is not to be used if you are allergic to any of its ingredients or to other aminoglycosides such as gentamicin. If you have bowel ulcers, inflammatory bowel disease or any intestinal obstruction, the drug is not advised to be taken. Medicines like penicillin and fludarabine and can interfere with its functioning.

Neomycin is to be taken orally with or without food. Do not use it for more than two weeks unless advised by your doctor. Continue using it for the full course of treatment to clear off the infection, even if you feel better.

To keep away any side effects, it may be taken at the lowest possible dosage and for the shortest period. Some of the side effects include stomach cramps, severe diarrhea, nausea and bloody stool.

Symptoms of overdose (rare due to poor oral bioavailability) include ototoxicity, nephrotoxicity, and neuromuscular toxicity. The treatment of choice following a single acute overdose appears to be the maintenance of good urine output of at least 3 mL/kg/hour.

Dialysis is of questionable value in the enhancement of aminoglycoside elimination. If required, hemodialysis is preferred over peritoneal dialysis in patients with normal renal function. Chelation with penicillin may be of benefit.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

The medicine is useful against the following conditions:

  • Hypersensitivity

  • Intestinal Obstruction

This medicine causes side effects such as:

  • Is It safe with alcohol?

    Interaction with alcohol is unknown. Please consult your doctor.
  • Are there any pregnancy warnings?

    Neopred tablet may be unsafe to use during pregnancy.
    Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Neopred tablet is probably safe to use during breastfeeding. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    There is no data available. Please consult doctor before consuming the drug.
  • Does this affect kidney function?

    There is no data available. Please consult doctor before consuming the drug.
  • Does this affect liver function?

    There is no data available. Please consult doctor before consuming the drug.
  • How long is the duration of effect?

    The effect of this medicine will be initiated with 1 - 2 hours after its administration.
  • What is the onset of action?

    This medicine will remain active for about 6 - 8 hours.
  • Are there any missed dose instructions?

    If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
  • Are there any overdose instructions?

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Below is the list of medicines, which contains Neomycin as ingredient

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This medication belongs to the class of an Aminoglycosides. It binds itself to 30S-subunit proteins and also 16S rRNA. It attaches irreversibly to a total of four nucleotides of 16S rRNA and one protein S12 amino acid. This causes interference when it comes to decoding the site.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Medicine

    • Decreased effect: May decrease GI absorption of digoxin and methotrexate.
    • Increased effect: Synergistic effects with penicillins.
    • Increased toxicity:
      • Oral neomycin may potentiate the effects of oral anticoagulants.
      • Increased adverse effects with other neurotoxic, ototoxic, or nephrotoxic drugs.
  • Interaction with Disease

    • Use with caution in patients with renal impairment, pre-existing hearing impairment, neuromuscular disorders. Neomycin is more toxic than other aminoglycosides when given parenterally.
    • Do not administer parenterally.
    • Topical neomycin is a contact sensitizer with sensitivity occurring in 5% to 15% of patients treated with the drug. It might cause symptoms include itching, reddening, edema, and failure to heal.
    • Do not use as peritoneal lavage due to significant systemic adsorption of the drug.

Ques: What is Neomycin? What is it used for?

Ans: This drug is an antibiotic used to treat bacterial skin infections. It may also be used to treat infected cuts and wounds. This medication stops the bacteria from growing, which helps to resolve the symptoms.

Ques: Is Neomycin effective?

Ans: Yes, it is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop consuming this drug too early, the symptoms may return or worsen.

Ques: How to use Neomycin?

Ans: Before using this drug, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If this medication gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.

Ques: What precautions do I need to take while using Neomycin?

Ans: Be careful not to get this medication into your eyes or mouth. Rinse off with plenty of water immediately and contact your doctor if in case it gets into your eyes. You must not use this drug if you are allergic to it or any of its ingredients. Using more than the prescribed dose may increase the side effects. Let your doctor know if you are planning to conceive. Women who are pregnant and breastfeeding should consume this drug only if prescribed by the doctor.

Ques: What should I do if I forget to use Neomycin?

Ans: If you forget to use this medication, do not worry, and continue using Neomycin as soon as you remember. However, if you are not sure and have any other doubts, please consult your doctor.

Ques: Is Neomycin safe?

Ans: Yes, it is completely safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Neomycin
What are the uses of Neomycin
What are the contraindications of Neomycin ?
What are the side effects of Neomycin ?
Key highlights of Neomycin
What are the dosage instructions?
Medicines containing Neomycin
How does this medication work?
What are the interactions of Neomycin ?
FAQs about Neomycin