Clobikem Gm Ointment is a very strong corticosteroid having a very high potency. It reduces the actions of chemicals that cause inflammation in the body. It is used to treat inflammation, redness and itching caused by a number of skin conditions such as eczema, allergic reactions, dermatitis, rashes and psoriasis.It is also used to treat several autoimmune diseases including vitiligo, alopecia areata, lichen planus, lichen sclerosus. It comes in the form of a shampoo, ointment, mousse and an emollient cream.
This medicine may have a few side effects that occur in rare cases. Some of them include experiencing a burning sensation after application, dry skin, redness of skin, cough, body pain, headache, itching of skin and sore throat. These effects should disappear in a few days as your body adjusts to the medication. Let your doctor know right away if any of these unlikely but serious side effects occur : stretch marks, skin thinning or discolouration, acne, hair bumps or excessive hair growth.
This medicine is not recommended to patients with known allergy to Clobikem Gm Ointment. It should not be given to a anyone younger than 12 years old. Tell your doctor if you are pregnant, plan to become pregnant or are breastfeeding while using this medicine. If you have any skin infection then make sure your doctor knows about it before prescribing this medicine.
Apply Clobikem Gm Ointment to the affected area, usually twice everyday in the morning and evening or as directed by your doctor. Apply this medication only on the skin. Make sure to not use it on the face, groin or underarms unless directed by your doctor. Do not apply smaller or larger amounts than prescribed. Avoid contact with eyes and do not consume the medicine. Do not discontinue using this medicine without consulting the doctor.
Pityriasis amiantacea is a disorder of the scalp. Some of the visible signs of this condition include adherent, silver, thick scales. The scales resemble the color of the asbestos and often surrounds the tufts of hair. While the condition is manageable, care should be taken to manage this condition right from its inception. Here is a brief overview of this scalp condition.
Origin of Pityriasis Amiantacea:
Pityriasis Amiantacea is inflammatory in nature. It comes from the seborrheic and psoriasis dermatitis spectrum. Experts are of the view that this condition is a result of the exaggerated response of the body to a primary condition of the scalp. Earlier studies have suggested that there is a possibility that Pityriasis Amiantacea may have originated from lichen planus, pyogenic infection and superficial fungal. In most of the cases, it has been witnessed that fungus has a close relation to this condition.
Exposure of Pityriasis Amiantacea and its diagnosis:
This condition has low exposure among females. It is mostly observed among, young adults, children, and adolescents. The diagnosis is done clinically. A specialist might prescribe dermoscopy to rule out other conditions of the scalp. If the result is positive, the scaling will reveal a diffused yellowish or whitish pattern. While the condition is local, it has all the possibilities to spread to other hairy parts of the body. Some experts are of the view that Pityriasis Amiantacea has a close association with temporary alopecia. While histopathology is not prescribed by most doctors, however, biopsy of the scalp is suggested in many cases.
Protein contact dermatitis (PCD) is an allergic skin reaction caused by proteins of either animal or plant origin. Four types of proteins can cause PCD: plant, animal, flour, and proteolytic chemicals. The risk factors for the improvement of PCD include a family history or general history of atopy, irritant dermatitis, an occupation or side interest, including exposure to one of these protein allergen agents. In PCD, avoiding these particular allergens is very important in order to avoid the reaction. Symptomatic help and relief might be found with transient corticosteroids, immunomodulatory operators, or antihistamines. Inpatient care might be important for PCD patients if the allergy is severe to the point that patients cannot take care of themselves or in the rare case that they encounter angioedema or extreme gastrointestinal problems.
Some short-term treatments may include high-power topical corticosteroids, for example, clobetasol propionate, to diminish the irritation and swelling. Topical tacrolimus 1% ointment might be a decent long-term solution for the allergies. Oral antihistamines might be prescribed also if highly serious allergy takes place. To enhance and improve the treatment of this condition, the initial steps are to recognise and maintain a strategic distance from the dependable allergen. PCD is a chronic procedure that tends to have phases of change during holidays and crumbles when you go back to work.
There are four types of protein contact dermatitis: animal, proteolytic enzymes, plant, and flour. The risk factors for this include protein allergens, atopy, and chronic dermatitis. There have been several theories proposed for protein contact dermatitis. Many Scientists are of the view that this occurs due to type 1 hypersensitivity.
Some are of the view that this results from type 1 and type 4 hypersensitivity reactions. Many also believe that this results due to a mediated immunoglobulin E hypersensitivity reaction. All the above three theories have been backed by enough proofs to support the model. No particular sexual or racial predilection is known for this infection. People can get affected with protein contact dermatitis at any age.
Proteins responsible for protein contact dermatitis:
There are four segments of proteins that can result in protein contact dermatitis.
Symptoms and diagnosis:
Protein contact dermatitis shows symptoms such as lichenification, erythematous papules, and dermatitis affecting the forearms. At times the fingertips get affected too. A doctor might prescribe a patch test followed by prick and scratch test. Other tests involve a fungal test, open application testing, radioallergosorbent testing, image studies, and biopsy.
The key to avoiding protein contact dermatitis is to stay away from the protein causing the disease. For short-term reliefs, a doctor can prescribe corticosteroids and antihistamines. A patient might have to get admitted to a hospital if the severity level of the disease is so much that the patient is suffering from gastrointestinal distress and angioedema. Medication involves oral dosage of antihistamines and clobetasol propionate.
Govt bans 344 drugs, including phensedyl, corex
Sr. No. Product name (irrational fdc)
1 aceclofenac + paracetamol + rabeprazole
2 nimesulide + diclofenac
3 nimesulide + cetirizine + caffeine
4 nimesulide + tizanidine
5 paracetamol + cetirizine + caffeine
6 diclofenac + tramadol + chlorzoxazone
7 dicyclomine + paracetamol + domperidone
8 nimesulide + paracetamol
9 paracetamol + phenylephrine + caffeine
10 diclofenac+ tramadol + paracetamol
11 diclofenac + paracetamol + chlorzoxazone + famotidine
12 naproxen + paracetamol
13 nimesulide + serratiopeptidase
14 paracetamol + diclofenac + famotidine
15 nimesulide + pifofenone + fenpiverinium + benzyl alcohol
16 omeprazole + paracetamol + diclofenac
17 nimesulide + paracetamol injection
18 tamsulosin + diclofenac
19 paracetamol + phenylephrine + chlorpheniramine + dextromethorphan + caffeine
20 diclofenac + zinc carnosine
21 diclofenac + paracetamol + chlorpheniramine maleate + magnesium trisillicate
22 paracetamol + pseudoephedrine + cetrizine
23 phenylbutazone + sodium salicylate
24 lornoxicam + paracetamol + trypsin
25 paracetamol + mefenamic acid + ranitidine + dicylomine
26 nimesulide + dicyclomine
27 heparin + diclofenac
28 glucosamine + methyl sulfonyl methane + vitamini d3 + maganese + boron + copper + zinc
29 paracetamol + tapentadol
30 tranexamic acid + proanthocyanidin
31 benzoxonium chloride + lidocaine
32 lornoxicam + paracetamol + tramadol
33 lornoxicam + paracetamol + serratiopeptidase
34 diclofenac + paracetamol + magnesium trisilicate
35 paracetamol + domperidone + caffeine
36 ammonium chloride + sodium citrate + chlorpheniramine maleate + menthol
37 paracetamol + prochlorperazine maleate
38 serratiopeptidase (enteric coated 20000 units) + diclofenac potassium & 2 tablets of doxycycline
39 nimesulide + paracetamol suspension
40 aceclofenac + paracetamol + famotidine
41 aceclofenac + zinc carnosine
42 paracetamol + disodium hydrogen citrate + caffeine
43 paracetamol + dl methionine
44 disodium hydrogen citrate + paracetamol
45 paracetamol + caffeine + codeine
46 aceclofenac (sr) + paracetamol
47 diclofenac + paracetamol injection
48 azithromycin + cefixime
49 amoxicillin + dicloxacillin
50 amoxicillin 250 mg + potassium clavulanate diluted 62.5 mg
51 azithromycin + levofloxacin
52 cefixime + linezolid
53 amoxicillin + cefixime + potassium clavulanic acid
54 ofloxacin + nitazoxanide
55 cefpodoxime proxetil + levofloxacin
56 azithromycin, secnidazole and fluconazole kit
57 levofloxacin + ornidazole + alpha tocopherol acetate
58 nimorazole + ofloxacin
59 azithromycin + ofloxacin
60 amoxycillin + tinidazole
61 doxycycline + serratiopeptidase
62 cefixime + levofloxacin
63 ofloxacin + metronidazole + zinc acetate
64 diphenoxylate + atropine + furazolidonee
65 fluconazole tablet, azithromycin tablet and ornidazole tablets
66 ciprofloxacin + phenazopyridine
67 amoxycillin + dicloxacillin + serratiopeptidase
68 azithromycin + cefpodoxime
69 lignocaine + clotrimazole + ofloxacin + beclomethasone
70 cefuroxime + linezolid
71 ofloxacin + ornidazole + zinc bisglycinate
72 metronidazole + norfloxacin
73 amoxicillin + bromhexine
74 ciprofloxacin + fluticasone + clotrimazole + neomycin is
75 metronidazole + tetracycline
76 cephalexin + neomycin + prednisolone
77 azithromycin + ambroxol
78 cilnidipine + metoprolol succinate + metoprolol tartrate
79 l-arginine + sildenafil
80 atorvastatin + vitamin d3 + folic acid + vitamin b12 + pyridoxine
81 metformin + atorvastatin
82 clindamycin + telmisartan
83 olmesartan + hydrochlorothiazide + chlorthalidone
84 l-5-methyltetrahydrofolate calcium + escitalopram
85 pholcodine + promethazine
86 paracetamol + promethazine
87 betahistine + ginkgo biloba extract + vinpocetine + piracetam
88 cetirizine + diethyl carbamazine
89 doxylamine + pyridoxine + mefenamic acid + paracetamol
90 drotaverine + clidinium + chlordiazepoxide
91 imipramine + diazepam
92 flupentixol + escitalopram
93 paracetamol + prochloperazine
94 gabapentin + mecobalamin + pyridoxine + thiamine
95 imipramine + chlordiazepoxide + trifluoperazine + trihexyphenidyl
96 chlorpromazine + trihexyphenidyl
97 ursodeoxycholic acid + silymarin
98 metformin 1000/1000/500/500mg + pioglitazone 7.5/7.5/7.5/7.5mg + glimepiride
99 gliclazide 80 mg + metformin 325 mg
100 voglibose+ metformin + chromium picolinate
101 pioglitazone 7.5/7.5mg + metformin 500/1000mg
102 glimepiride 1mg/2mg/3mg + pioglitazone 15mg/15mg/15mg + metformin 1000mg/1000mg/1000mg
103 glimepiride 1mg/2mg+ pioglitazone 15mg/15mg + metformin 850mg/850mg
104 metformin 850mg + pioglitazone 7.5 mg + glimepiride 2mg
105 metformin 850mg + pioglitazone 7.5 mg + glimepiride 1mg
106 metformin 500mg/500mg+gliclazide sr 30mg/60mg + pioglitazone 7.5mg/7.5mg
107 voglibose + pioglitazone + metformin
108 metformin + bromocriptine
109 metformin + glimepiride + methylcobalamin
110 pioglitazone 30 mg + metformin 500 mg
111 glimepiride + pioglitazone + metformin
112 glipizide 2.5mg + metformin 400 mg
113 pioglitazone 15mg + metformin 850 mg
114 metformin er + gliclazide Mr. + voglibose
115 chromium polynicotinate + metformin
116 metformin + gliclazide + piogllitazone + chromium polynicotinate
117 metformin + gliclazide + chromium polynicotinate
118 glibenclamide + metformin (sr)+ pioglitazone
119 metformin (sustainded release) 500mg + pioglitazone 15 mg + glimepiride 3mg
120 metformin (sr) 500mg + pioglitazone 5mg
121 chloramphenicol + beclomethasone + clomitrimazole + lignocaine
122 of clotrimazole + ofloxaxin + lignocaine + glycerine and propylene glycol
123 chloramphennicol + lignocaine + betamethasone + clotrimazole + ofloxacin + antipyrine
124 ofloxacin + clotrimazole + betamethasone + lignocaine
125 gentamicin sulphate + clotrimazole + betamethasone + lignocaine
126 clotrimazole + beclomethasone + ofloxacin + lignocaine
127 becloemthasone + clotrimazole + chloramphenicol + gentamycin + lignocaine ear
128 flunarizine + paracetamole + domperidone
129 rabeprazole + zinc carnosine
130 magaldrate + famotidine + simethicone
131 cyproheptadine + thiamine
132 magaldrate + ranitidine + pancreatin + domperidone
133 ranitidine + magaldrate + simethicone
134 magaldrate + papain + fungul diastase + simethicone
135 rabeprazole + zinc + domperidone
136 famotidine + oxytacaine + magaldrate
137 ranitidine + domperidone + simethicone
138 alginic acid + sodium bicarbonate + dried aluminium hydroxide + magnesium hydroxide
139 clidinium + paracetamol + dicyclomine + activated dimethicone
140 furazolidone + metronidazole + loperamide
141 rabeprazole + diclofenac + paracetamol
142 ranitidine + magaldrate
143 norfloxacin+ metronidazole + zinc acetate
144 zinc carnosine + oxetacaine
145 oxetacaine + magaldrate + famotidine
146 pantoprazole (as enteric coated tablet) + zinc carnosine (as film coated tablets)
147 zinc carnosine + magnesium hydroxide + dried aluminium hydroxide + simethicone
148 zinc carnosine + sucralfate
149 mebeverine & inner hpmc capsule (streptococcus faecalis + clostridium butyricum + bacillus
Mesentricus + lactic acid bacillus)
150 clindamycin + clotrimazole + lactic acid bacillus
Avoid this combinations and be safe.
Vitiligo is a long-term skin condition characterized by patches of the skin losing their pigment. The patches of skin affected become white and usually have sharp margins. The hair from the skin may also become white. The inside of the mouth and nose may also be involved. Typically both sides of the body are affected. often the patches begin on areas of skin that are exposed to the sun. It is more noticeable in people with dark skin. Vitiligo may result in psychological stress and those affected may be stigmatized.
The exact cause of vitiligo is unknown. It is believed to be due to genetic susceptibility that is triggered by an environmental factor such that an autoimmune disease occurs. This results in the destruction of skin pigment cells. Risk factors include a family history of the condition or other autoimmune diseases, such as
Hyperthyroidism, alopecia areata, and pernicious anemia. It is not contagious. Vitiligo is classified into two main types: segmental and non-segmental. Most cases are non-segmental, meaning they affect both sides; and in these cases, the affected area of the skin typically expands with time. About 10% of cases are segmental, meaning they mostly involve one side of the body; and in these cases, the affected area of the skin typically does not expand with time. Diagnosis can be confirmed by tissue biopsy.
There is no known cure for vitiligo. For those with light skin, sunscreen and makeup are all that is typically recommended. Other treatment options may include
Steroid creams or phototherapy to darken the light patches. Alternatively, efforts to lighten the unaffected skin, such as with hydroquinone, may be tried. A number of surgical options are available for those who do not improve with other measures. A combination of treatments generally has better outcomes. Counselling to provide emotional support may be useful.
Globally about 1% of people are affected by vitiligo. Some populations have rates as high as 2–3%. Males and females are equally affected. About half show the disorder before age 20 and most develop it before age 40. Vitiligo has been described since ancient history.
Signs and symptoms-
Classification attempts to quantify vitiligo have been analyzed as being somewhat inconsistent, while recent consensus have agreed to a system of segmental vitiligo (sv) and non-segmental vitiligo (nsv). Nsv is the most common type of vitiligo.
In non-segmental vitiligo (nsv), there is usually some form of symmetry in the location of the patches of depigmentation. New patches also appear over time and can be generalized over large portions of the body or localized to a particular area. Extreme cases of vitiligo, to the extent that little pigmented skin remains, are referred to as vitiligo universalis. Nsv can come about at any age (unlike segmental vitiligo, which is far more prevalent in teenage years).
Classes of non-segmental vitiligo include the following:
Segmental vitiligo (sv) differs in appearance, cause, and frequency of associated illnesses. Its treatment is different from that of nsv. It tends to affect areas of skin that are associated with dorsal roots from the spinal cord and is most often unilateral. It is much more stable/static in course and its association with autoimmune diseases appears to be weaker than that of generalized vitiligo. SV does not improve with topical therapies or uv light, however surgical treatments such as cellular grafting can be effective.
Chemical leukoderma is a similar condition due to multiple exposures to chemicals. Vitiligo however is a risk factor. Triggers may include inflammatory skin conditions, burns, intralesional steroid injections and abrasions.
Other conditions with similar symptoms include the following:
There is no cure for vitiligo but several treatment options are available. The best evidence is for applied steroids and the combination of ultraviolet light in combination with creams. Due to the higher risks of skin cancer, the united kingdom's national health service suggests phototherapy only be used if primary treatments are ineffective. Lesions located on the hands, feet, and joints are the most difficult to repigment; those on the face are easiest to return to the natural skin color as the skin is thinner in nature.