Mifepristone is a steroid used to terminate a pregnancy. It inhibits the secretion of progesterone that is needed to maintain the pregnancy. It should only be used if the pregnancy is within 70 days (10 weeks).
It is recommended that you do not use it if you are over 10 weeks pregnant. It can only be bought with a prescription. For a complete medical termination of the pregnancy, Mifepristone is used with Misoprostol. Mifepristone is taken as a tablet once. After 24-48 hours, Misoprostol is taken.
A women should not take Mifepristone if she is/has:
- An ectopic pregnancy
- Treated with long-term corticosteroid medicines
- Inherited porphyria
- Problem with the adrenal glands
- Bleeding problems or is taking anticoagulant (blood-thinning) medication
- An intrauterine device (IUD) in place, it must be removed before taking this medication.
The dosage for this medication will be prescribed by your doctor depending on your age, weight, health, and current condition. After 7 days, you must visit your doctor to check if you are still pregnant. Also, track the quantity and frequency of the bleeding.
Mifepristone is primarily used for the treatment of condition like:
Unexplained Vaginal Bleeding
Chronic Adrenal Failure
Other Bleeding Disorders
How long is the duration of effect?The effect of this medicine lasts for an average duration of 7-10 days.
What is the onset of action?
Mifepristone starts producing the required effects within 1-2 hours of administration.
Are there any pregnancy warnings?
It is advised that Mifepristone is used to terminate a pregnancy that is within 63-70 days. Use of this drug to control elevated blood sugar level should not be done if you are pregnant.
Is it habit forming?
It is not habit forming.
Are there any breast-feeding warnings?
It is recommended that you do not breastfeed your child if the administration of this drug is highly necessary.
Is It safe with alcohol?
Interaction with alcohol is still unknown. Consult your doctor before proceeding
Is it safe to drive while on this medicine?
Mifepristone may cause sleepiness. It is advised that you do not drive if you are experiencing this side-effect.
Does this affect kidney function?
There is no reported impairment to the kidney functioning.
Does this affect liver function?
There is no reported impairment to the liver functioning.
Are there any missed dose instructions?
For termination of pregnancy, it is a single dose therapy; it is not possible to miss a dose. If you are taking it for controlling blood sugar level and miss a dose, take it as soon as possible. But do not double dose.
Are there any overdose instructions?
If you overdose on Mifepristone, contact your physician right away.
Below is the list of medicines, which contains Mifepristone as ingredient
This medication works by blocking the effect of progesterone by competitively binding to the specific receptors and sensitizing the inner linings of the uterus inducing bleeding and contractions. It also blocks the effect of cortisol at the specific receptors and reducing the effect caused by an excess of this hormone.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Medicine
Mifepristone severely interacts with the following drugs- dexamethasone, erythromycin, hydrocortisone, ketoconazole, simvastatin, pimozide, warfarin and ergotamine.
Interaction with Food
It is recommended that you avoid grapefruit juice while taking this medication. It may modify the effects of the drug.
Interaction with Disease
There are no known disease interactions.
Ques: What is Mifepristone?
Ques: How and in what dose should I consume?
Ques: What should I expect after taking Mifepristone?
Ques: Can Mifepristone affect my future chances of getting pregnant?
Ques: What are the common side effects of taking Mifepristone?
Mifepristone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:https://druginfo.nlm.nih.gov/drugportal/name/mifepristone
Mifepristone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:https://go.drugbank.com/drugs/DB00834
MIFEPRISTONE tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=MIFEPRISTONE
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