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Overview

Glycomet 500 MG Tablet SR

Manufacturer: Usv Ltd
Medicine composition: Metformin
Prescription vs.OTC: Prescription by Doctor required

Glycomet 500 MG Tablet SR is a drug that helps maintain balanced blood sugar levels in the body. It is used to treat Type 2 diabetes, heart disorders and polycystic ovary syndrome.

Glycomet 500 MG Tablet SR works by decreasing the amount of glucose produced by the liver. It suppresses the quantity of glucose that the liver releases in the body. Thus, it lowers the blood sugar levels in the body of a patient suffering from Type 2 diabetes. Glycomet 500 MG Tablet SR also increases your sensitivity to insulin, enabling your body to absorb larger quantities of glucose. This drug is available in oral solution or even tablet form.

Glycomet 500 MG Tablet SR is an oral drug that is used to control and balance blood sugar levels. This medication is used in the treatment of conditions such as type 2 diabetes, obesity, cardiovascular diseases, hypertension and polycystic ovarian syndrome. If you do not manage the condition of diabetes, it can result in kidney failure, obesity and heart disorders. Therefore, Glycomet 500 MG Tablet SR helps keep your blood sugar levels low and your diabetes in check.

Glycomet 500 MG Tablet SR does not increase the amount of insulin in the body; instead, it decreases the production of sugar. The liver of patients, who suffer from type 2 diabetes, produces thrice the amount of glucose and their bodies do not have the capacity to absorb these large amounts of glucose. Glycomet 500 MG Tablet SR is effective in lowering the amount of glucose that the liver releases. It also decreases your appetite and increases your body’s sensitivity to insulin, thus, reducing the amount of glucose that is absorbed by your blood. An increased sensitivity to insulin also lowers your levels of cholesterol and helps you to lose weight.

Glycomet 500 MG Tablet SR is available in the form of tablets as well as oral solutions. The dosage that the doctor recommends for your treatment will be based on your age, your condition, the severity of your condition and the other medications you are currently taking. You should follow the course of this treatment until it is completed, and do not skip out on a dose.

In some cases, it is advisable for the patients of certain conditions to avoid taking this medication. You should inform your doctor before taking this medicine, if you suffer from conditions like liver disease, kidney disorders, heart disease, allergies and diabetic ketoacidosis. Pregnant women, women who are breast-feeding their infants and children below ten years should not take this medicine.

The common side effects of Glycomet 500 MG Tablet SR include diarrhea, dizziness, headaches, vomiting and stomach cramps. Consuming this medicine with food can lower your risk of developing the side effects. One rare yet major side effect of Glycomet 500 MG Tablet SR is lactic acidosis. It is build up of lactic acid in the blood, which can be fatal. This side effect causes symptoms such as muscle weakness, stomach aches, nausea, irregular heartbeat, difficulty breathing, cold or numb sensation in the arms and legs. You should seek emergency medical aid, if you detect any of these symptoms. It is important to avoid drinking alcohol while taking this medicine, since it can increase your risk of developing lactic acidosis.

Type diabetes
Type II Diabetes Mellitus
Glycomet 500 MG Tablet SR improves blood glucose levels in adults and children. The drug is to be taken with proper diet and regular exercise.
Glycomet 500 MG Tablet SR is also used to treat this hormonal condition known as Polycystic ovary syndrome.
Impaired kidney function
Glycomet 500 MG Tablet SR is not recommended for patients having an impaired kidney function. This can be attributed to other risk factors like shock, heart attack, and Septicemia.
Glycomet 500 MG Tablet SR is not recommended for use if you have a known history of allergy to it.
Metabolic Acidosis
Glycomet 500 MG Tablet SR is not recommended for use in patients with unbalanced acid levels in the body.
In addition to its intended effect, Glycomet 500 MG Tablet SR may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Nausea and vomiting Moderate Common
Diarrhea Moderate Common
Abdominal pain Moderate Common
Hypoglycemia Major Common
Lactic Acidosis Major Rare
Weakness Moderate Less Common
Chest discomfort Moderate Less Common
Headache Minor Less Common
Running nose Minor Less Common
Belching and Heartburn Minor Common
Swollen joints Minor Rare
How long the duration of effect?
The effect lasts for an average duration of 4 to 8 hours.
what is the onset of action?
The peak effect of this medicine can be observed after 1-3 hours of administration.
Are there any pregnancy warnings?
This medicine is not recommended for use in pregnant women owing to the risk of abnormalities in the fetus. Alternate means of blood sugar control like insulin therapy should be considered during pregnancy.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
This medicine is not recommended for use in breastfeeding women owing to the risk of adverse effects on the baby. Alternate means of blood sugar control like insulin therapy should be considered in such cases. If it becomes absolutely necessary to take this medicine, then breastfeeding should be discontinued.
Below is the list of medicines, which have the same composition, strength and form as Glycomet 500 MG Tablet SR, and hence can be used as its substitute.
Alkem Laboratories Ltd
Aristo Pharmaceuticals Pvt.Ltd
Abbott India Ltd
Wockhardt Ltd
Missed Dose instructions
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.
Overdose instructions
Contact a doctor immediately if an overdose is suspected. Some overdosages could lead to Lactic Acidosis which requires immediate medical intervention.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Lactic Acidosis Major
You should report the incidence of conditions like kidney impairment, heart disease, severe diarrhea, septicemia to the doctor before taking Glycomet 500 MG Tablet SR. Supervised dosing and monitoring of blood sugar levels might be required in such cases. Any signs and symptoms indicative of the above-mentioned conditions should be reported immediately.
Vitamin B12 deficiency Moderate
Inform the doctor about incidences of anemia or Vitamin B12 deficiency so that suitable Vitamin supplements can be prescribed if needed.Vitamin B1 deficiency
Interaction with Alcohol
Ethanol Moderate
Avoid using alcohol while taking this medicine. Symptoms such as prolonged weakness and muscle pain, lack of sleep, breathing difficulties after alcohol intake should be reported to the doctor immediately.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Iodinated Contrast Media Major
Discontinue the usage of Glycomet 500 MG Tablet SR at least 48 hours prior to the intake of Iodinated Contrast media. Inform the doctor about Metformin use so that it can be temporarily discontinued.
Gatifloxacin Major
Report the usage of either of the medicine to the doctor. Use of Glycomet 500 MG Tablet SR is not recommended along with Gatifloxacin and suitable alternates should be used instead.
Amlodipine Moderate
Report the use of either of the medication to the doctor as dose adjustment and safety monitoring may be required.
Aloe Vera Moderate
Consult your doctor for use of aloe vera while taking Glycomet 500 MG Tablet SR. Suitable dose adjustments and safety monitoring may be required if the intended use is for a long duration.
Estradiol Moderate
Consult your doctor if you are planning to take Estradiol while taking Glycomet 500 MG Tablet SR. Dose adjustment might be required in such cases. It is advised to consult your doctor before starting or stopping any medication while taking metformin.
What are you using Glycomet 500 MG Tablet SR for?
Type II Diabetes Mellitus
Other
Polycystic Ovary Syndrome
How much was the improvement?
Average
Excellent
Poor
How long did it take before seeing improvement?
More than 2 days
Within 2 hours
Within a day
Within 6 hours
Within 2 days
How frequently did you take this medicine?
Once a day
Twice a day
Not taking on daily level
Four times A Day
Thrice a day
How did you take this medicine?
With Food
With or without food
Empty stomach
What were the side effects of this medicine?
Weakness
Abdominal Pain
Nausea and vomiting
Headache
Lactic Acidosis
Hypoglycemia
Chest discomfort
No Side Effects
Diarrhea
Running nose
Belching and Heartburn

Popular Questions & Answers

Hi Sir, I want to ask you that can glycomet cause full blindness in glycomet patients.

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
Hi Sir, I want to ask you that can glycomet cause full blindness in glycomet patients.
No. glycomet cannot cause full blindness in diabetes patients.and in case they get blindness it may be due to excess , uncontrolled diabetes or eye diseases
1 person found this helpful

What is the difference between the tablet sr 500 and glycomet 250 mg? I fee sr500 is not responding after changing from glycomet 250 mg.

MBBS, CCEBDM, Diploma in Diabetology, Diploma in Clinical Nutrition & Dietetics, Cetificate Course In Thyroid Disorders Management (CCMTD)
Endocrinologist, Hubli-Dharwad
What is the difference between the tablet sr 500 and glycomet 250 mg? I fee sr500 is not responding after changing fr...
The difference is sr means sustained release, where the drug metformin is released over 12 hrs at a constant rate and the drug action is prolonged. Normal tablet releases the drug in about an hour or so, action lasts for lesser time. Sr tablets also produce lesser gastro intestinal side effects.
2 people found this helpful

Difference in glycomet gp-1 and glycomet 500 what are conditions when glimepiride and metformin to be taken individual or as combination, if sugar in the range of 140 in fasting and 180-200 after lunch can we take glycomet 500 alone.

MBBS, CCEBDM, Diploma in Diabetology, Diploma in Clinical Nutrition & Dietetics, Cetificate Course In Thyroid Disorders Management (CCMTD)
Endocrinologist, Hubli-Dharwad
Difference in glycomet gp-1 and glycomet 500 what are conditions when glimepiride and metformin to be taken individua...
Mr. lybrate-user, Thanks for the query. Glimepiride stimulates betacells to secrete insuli. Metformin is supposed to reduce insulin resistance and slow down glucose absorption from the intestine. Plus it also has many more beneficial functions. Usually both these are used togeter to control increased blood glucose. In newly diagnosed patients metformin alone is used. In some both drugs are used together. Which drug to take for a particular level can be decided by the treating doctor. Thanks.
1 person found this helpful

Please tell me that whether glycomet trio2 tablet is better taking before morning meal or before night meal.

MD - General Medicine, MBBS Bachelor of Medicine and Bachelor of Surgery, Post Graduate Diploma In Diabetology (PGDD), Middlesex university London, Stanley Medical college Chennai
Diabetologist, Chennai
Please tell me that whether glycomet trio2 tablet is better taking before morning meal or before night meal.
Diabetic medications can be taken, as per your diet, occupation this medicine can be taken half tablet twice a day along with food.

Slimovita is prescribed by a doctor. But I am already taking glycomet 1000 mg. Should I continue both?

MD - Homeopathy, BHMS
Homeopath, Vadodara
Slimovita is prescribed by a doctor. But I am already taking glycomet 1000 mg. Should I continue both?
If you already are taking a medicine then you should have informed your doctor.. If he know it and still prescribed the medicine then you should take it..
1 person found this helpful

Popular Health Tips

MD - Internal Medicine, CCMD(Diabetology), PG Course in Diabetology, ADVANCED CERTIFICATE COURSE IN DIABETES
Diabetologist, Dehradun
vitamin B12 should be checked periodically in diabetics on tab.Metformin
3 people found this helpful

MD - Diabetology, Membership of the Royal College of Surgeons (MRCS), MBBS
Endocrinologist, Kochi
A few patients have enquired about the 1st line of drug for Type 2 diabetes. Usually, Metformin is the first drug to be given in non-pregnant Type 2 Diabetes, along with advice on diet changes, exercises & lifestyle modifications (quit smoking, quit or reduce alcohol, etc). But in a few patients, Insulin might be used as 1st line. But even in such patients, Metformin is given along with Insulin.
13 people found this helpful

DELAYING INSULIN INITIATION

MD - Internal Medicine, CCMD(Diabetology), PG Course in Diabetology, ADVANCED CERTIFICATE COURSE IN DIABETES
Diabetologist, Dehradun
DELAYING INSULIN INITIATION
For patients with type 2 diabetes treated with metformin, add-on sitagliptin is associated with a lower risk for insulin initiation than add-onsulphonylureas like glimepride, according to a study published in diabetes, obesity and metabolism.
22 people found this helpful

diabetic double risk of parkinsonism

MBBS, MD - Internal Medicine
Internal Medicine Specialist, Faridabad
diabetic double risk  of parkinsonism
Diabetes more than doubles the risk of developing Parkinson's disease while metformin therapy protects against that risk, according to research published in the publication Parkinsonism and Related Disorders.

Parkinson's disease is a disorder of the brain that leads to tremors and difficulty with walking, movement and coordination. It most often develops in people age 50 or older and is one of the most common nervous system disorders of the elderly, according to the National Institutes of Health. There is no known cure.

The major 12-year study in Taiwan found that while diabetes increases the risk of Parkinson's 2.2 fold, including metformin in the therapy negates that risk.

“An exciting aspect of the finding is that metformin seems to be working to protect the brain against neurodegeneration which contributes to Parkinsonism. This means it may also be considered a relevant therapy for the prevention of dementia as well,” said Mark Wahlqvist, professor at the National Health Research Institutes in Taiwan and lead author of the study.

Metformin is the first-line medication for patients with type 2 diabetes. This affordable and commonly prescribed oral drug lowers blood glucose levels by decreasing the amount of glucose produced by the liver and enhancing insulin action. It's a type of biguanide drug used since the 1950s with a relatively safe record.

Researchers also found that use of sulfonylurea drugs, a common treatment for diabetes, further increases the risk by about 57 percent.

Sylfonylureas are a category of oral medications that stimulate the beta cells of the pancreas to release more insulin, according to the American Diabetes Association. Sylfonylurea drugs have been in use since the 1950s and include glipizide, glyburide, glimepiride and chlorpropamide.

Researchers theorize that metformin may re-set the regulation of energy metabolism in the brain cells. They suspect that exercise and diet may have the same energy regulating effect.

The study does not examine the mechanism behind metformin's protective effect on the brain. Researchers say that additional research is needed in this area.

Past research has shown that metformin reduces cardiovascular mortality and several cancers, including those of the large bowel, liver and pancreas.
36 people found this helpful

MD - Pulmonary, DTCD
Pulmonologist, Faridabad
FIXED DOSE COMBINATION OF MEDICINE.
As per LANCET an authoritative medical journal,fixed dose combinations of medicine are being marketed in India without detailed trial and are of unproven efficacy.Metformin used in combination with other anti diabetic medicine is of limited value.They are advised to the patient that you have to take less number of tablet but efficacy is compromised. It is better to take medicine of single ingrediant except few.
4 people found this helpful

Table of Content

About Glycomet 500 MG Tablet SR
When is Glycomet 500 MG Tablet SR prescribed?
What are the contraindications of Glycomet 500 MG Tablet SR?
What are the side effects of Glycomet 500 MG Tablet SR?
Key highlights of Glycomet 500 MG Tablet SR
What are the substitutes for Glycomet 500 MG Tablet SR?
What are the dosage instructions?
Where is the Glycomet 500 MG Tablet SR approved?
What are the interactions for Glycomet 500 MG Tablet SR?