Get Dettol Kit worth Rs. 130 for just Rs. 4
Common Specialities
Common Issues
Common Treatments


Dserin Gm 50 Mg/750 Mg Tablet

Manufacturer: Knoll Pharmaceuticals Ltd
Medicine composition: Diacerein, Glucosamine
Prescription vs.OTC: Prescription by Doctor required

Dserin Gm 50 Mg/750 Mg Tablet is anti-inflammatory analgesics and antipyretic drug that is used to treat problems such as joint diseases like osteoarthritis. It helps to minimize the friction and roughness between the joints. It also has properties that are important to improve the cartilage strength.

If you are hypersensitive to Dserin Gm 50 Mg/750 Mg Tablet or any of its ingredients, then it should not be prescribed. If you have severe kidney problems, you should take half the usual dosage. It is not to be used for pregnant and lactating women, for those with liver problems, and also for those that are 15 years and below.

The dosage is usually taken with food, twice in a day for 2-4 weeks. When it is taken with food, the rate of absorption is increased by almost 25%.

Some of the side effects that may appear at the beginning of the treatment are changes in the colour of urine, diarrhea, eczema, abdominal pain and rashes. Consult a doctor immediately if you experience such symptoms.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Rheumatologist before using this medicine.

In addition to its intended effect, Dserin Gm 50 Mg/750 Mg Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
Caution is advised when driving or operating machinery.
Does this affect kidney function?
There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Dserin Gm 50 Mg/750 Mg Tablet is a prodrug that metabolizes to rhein that is works by reducing cartilage destruction. It blocks the interleukin-1 beta protein’s action that is responsible for destruction of cartilage and inflammation causing osteoarthritis like degenerative joint disorders. The drug is specific in action and does not inhibit the synthesis of prostaglandin.
What are you using Dserin Gm 50 Mg/750 Mg Tablet for?
Rheumatoid Arthritis
How much was the improvement?
How long did it take before seeing improvement?
Within 2 days
How frequently did you take this medicine?
Once a day
How did you take this medicine?
With Food
What were the side effects of this medicine?
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I am 75 years old. I am asked to take Diacerein and Glucosamine tablets twice daily for my Knee arthritis. Is it OK?

Homeopath, Chandigarh
I am 75 years old. I am asked to take Diacerein and Glucosamine tablets twice daily for my Knee arthritis. Is it OK?
You may take it for some days. F you are feeling better then it's okay. Take it only for ten days and see the results.
1 person found this helpful

Facing with knee pain,is their any medicin without side effects?present I am using topnack sr once in a week.lost week I went to doctor.he was given Diacerein Capsuls IP 50 give me advice.

Dip. SICOT (Belgium), MNAMS, DNB (Orthopedics), MBBS
Orthopedist, Delhi
Hi , This is Dr Akshay from Fortis Hospital. Kindly let me know your age and upload your x rays for us to prescribe some medications. Meanwhile continue with you physiotherapy. Thanks & Regards Dr Akshay Kumar Saxena

I am suffering from severe to moderate knee pain from last 2 years. I visited my family Doc couple of times and he prescribed Glucosamine and Calcium Caps for 1 months but it didn't work. After small research in glass I found that Diacerein 50 mg would be more helpful. I would I to know the dosage and another substitute medicine besides Diacerein.

Ayurveda, Sonipat
I am suffering from severe to moderate knee pain from last 2 years. I visited my family Doc couple of times and he pr...
Diacerein. The recommended starting dose is 50 mg once daily with evening meal for the first 2 to 4 weeks of treatment, after which the recommended daily dose is 50 mg twice daily. The treatment should be taken with food, one with breakfast and the other with evening meal. The capsules must be swallowed intact, without opening them, together with a glass of water.
9 people found this helpful

Popular Health Tips

Diploma in Nutrition
Dietitian/Nutritionist, Hyderabad
Joint Replacement Surgery: Health Information Basics for You and Your Family

What Can Happen to My Joints?
Joints can be damaged by arthritis and other diseases, injuries, or other causes. Arthritis or simply years of use may cause the joint to wear away. This can cause pain, stiffness, and swelling. Bones are alive, and they need blood to be healthy, grow, and repair themselves. Diseases and damage inside a joint can limit blood flow, causing problems.

What Is a New Joint Like?
A new joint, called a prosthesis (praas-THEE-sis), can be made of plastic, metal, or both. It may be cemented into place or not cemented, so that your bone will grow into it. Both methods may be combined to keep the new joint in place.
A cemented joint is used more often in older people who do not move around as much and in people with “weak” bones. The cement holds the new joint to the bone. An uncemented joint is often recommended for younger, more active people and those with good bone quality. It may take longer to heal, because it takes longer for bone to grow and attach to it.
New joints generally last at least 10 to 15 years. Therefore, younger patients may need to have the same damaged joint replaced more than once.

Most of the people feel a pain still after successful replacement

You can avoid joint replacement surgery, if you can really recover the damaged joint, Joint damage may cause due to above said condition. Glucosamine is marketed to support the structure and function of joints. But Glucosamine should be taken with combination based on the health condition of the person. Please consult a doctor before you proceed with this. Or you can reach us. Lets go with food supplement of glucosamine, we help you with natural from nature.
3 people found this helpful

General Physician (AM)
Alternative Medicine Specialist, Chandigarh
Tips to prevent joint degeneration:

Joint degeneration is progressive and signs and symptoms gradually worsen over time. Factors like age, gender, and sometimes heredity all play a role and, although there is no cure, there are ways to stave off more pain or compromised mobility later on in life:

1. Control your weight
Maintaining a healthy weight can go a long way toward protecting your joints. Obesity is a clear risk factor for developing some form of joint degeneration. Being overweight strains the joints, particularly those that bear a lot of weight, such as the knees and hips, causing the cartilage to wear away.

2. Stay Active
Although high intensity exercise, direct joint impact and injury from exercise can cause cartilage to break down faster, lack of any exercise may cause the muscles that run along the front of the thigh to remain weak, causing impact on the joints.

Exercise keeps joints healthy and is a key part of both joint degeneration prevention and symptom alleviation. Low impact options such as swimming, yoga, and walking push your heart rate up without putting further strain on joints. Strength training is also important as it increases muscle and bone health.

If fear of joint pain after exercise keeps you from exercising, try using heat and cold on painful joints, or take pain relievers, which may make it easier to exercise and stay active. The safest exercises are those that place the least body weight on the joints, such as bicycling, swimming, and other forms of water exercise.

3. Stand up
Are you guilty of slouching at your desk all day in front of a computer? Good posture alleviates stress on many important joints; it is therefore important to maintain the two natural curves of your spine, whether sitting or standing. The two natural curves are the concave curves between the base of your head and your shoulders, and the one from your upper back to the base of your spine.

4. Supplement with Daily Nutrients
Research indicates that glucosamine supplements help relieve pain and stiffness associated with joint degeneration, particularly when combined with appropriate lifestyle modifications, such as a balanced diet and exercise.

Glucosamine sulphate occurs naturally in the body, and seemingly plays a part in the repair and maintenance of joint cartilage. It is used by the body to produce a variety of other chemicals that are involved in building the connective tissue matrix (tendons, ligaments, cartilage) and the synovial fluid (thick fluid around the joints). Protection of this is critical to avoid suffering later in life.

Glucosamine sulphate has also been proven to reduce symptoms of joint degeneration, including pain (48%), compared to Ibuprofen (52%), which has significantly more side effects (35%) than glucosamine sulphate (6%), as reported in one clinical trial.

Eating fruits such as berries, apples, plums, and peaches that contain antioxidants may also help decrease inflammation.

5. Relax
Stress in general is bad for the body. It can lead to lack of sleep and depression, both of which take a toll on your body. Relaxation techniques such as meditation and yoga can help reduce levels of stress and improve your overall health.
So Remain Relaxed,Stress free.
6 people found this helpful

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha

4 ways to put off joint replacement
Tip #1: Lose weight: For every extra pound you carry, you put about three pounds of additional pressure on your knees and multiply the pressure on your hips by six. If you have arthritis, losing just 15 pounds can cut your knee pain in half.

Tip #2: Take care when using your joints: Poor posture and using the wrong techniques during your daily activities add more stress to damaged joints. By standing up straight instead of slouching, you can protect the joints in your neck, hips, and knees. Also use the proper technique when lifting or carrying anything heavy. If any activity hurts, stop doing it right away.

Tip #3: Try nonsurgical approaches before turning to surgery: Treatment with steroids is one approach. Benefits can last anywhere from four to six months. However, this doesn't work for everyone. Visco supplementation involves injecting a lubricating fluid into damaged knee joints to treat osteoarthritis

Tip #4: Get pain relief: Instead of heading straight to your doctor to treat sore joints, try taking an over-the-counter pain reliever. Take them for the shortest possible time to relieve your discomfort. There is also some evidence that the dietary supplement glucosamine chondroitin can lead to subtle improvements in arthritis pain.
1 person found this helpful

Options Other Than Knee Replacement

Orthopedist, Delhi
Options Other Than Knee Replacement

There is no cure for arthritis but there are a number of treatments that may help relieve the pain and disability it can cause.

  • As with other arthritic conditions, initial treatment of arthritis of the knee is nonsurgical. Your doctor may recommend a range of treatment options.
  • Lifestyle modifications. Some changes in your daily life can protect your knee joint and slow the progress of arthritis.
  • Minimize activities that aggravate the condition, such as climbing stairs.
  • Switching from high impact activities (like jogging or tennis) to lower impact activities (like swimming or cycling) will put less stress on your knee.
  • Losing weight can reduce stress on the knee joint, resulting in less pain and increased function.
  • Physical therapy. Specific exercises can help increase range of motion and flexibility, as well as help strengthen the muscles in your leg. Your doctor or a physical therapist can help develop an individualized exercise program that meets your needs and lifestyle.
  • Assistive devices. Using devices such as a cane, wearing shock-absorbing shoes or inserts, or wearing a brace or knee sleeve can be helpful. A brace assists with stability and function, and may be especially helpful if the arthritis is centered on one side of the knee. There are two types of braces that are often used for knee arthritis: an" unloader" brace shifts weight away from the affected portion of the knee, while a" support" brace helps support the entire knee load.
  • Other remedies. Applying heat or ice, using pain-relieving ointments or creams, or wearing elastic bandages to provide support to the knee may provide some relief from pain.
  • Medications. Several types of drugs are useful in treating arthritis of the knee. Because people respond differently to medications, your doctor will work closely with you to determine the medications and dosages that are safe and effective for you.
  • Over-the-counter, non-narcotic pain relievers and anti-inflammatory medications are usually the first choice of therapy for arthritis of the knee. Acetaminophen is a simple, over-the-counter pain reliever that can be effective in reducing arthritis pain.
  • Like all medications, over-the-counter pain relievers can cause side effects and interact with other medications you are taking. Be sure to discuss potential side effects with your doctor.
  • Another type of pain reliever is a nonsteroidal anti-inflammatory drug, or nsaid (pronounced" en-said"). Nsaids, such as ibuprofen and naproxen, are available both over-the-counter and by prescription. A cox-2 inhibitor is a special type of nsaid that may cause fewer gastrointestinal side effects. Common brand names of cox-2 inhibitors include celebrex (celecoxib) and mobic (meloxicam, which is a partial cox-2 inhibitor). A cox-2 inhibitor reduces pain and inflammation so that you can function better. If you are taking a cox-2 inhibitor, you should not use a traditional nsaid (prescription or over-the-counter). Be sure to tell your doctor if you have had a heart attack, stroke, angina, blood clot, hypertension, or if you are sensitive to aspirin, sulfa drugs or other nsaids.
  • Corticosteroids (also known as cortisone) are powerful anti-inflammatory agents that can be injected into the joint these injections provide pain relief and reduce inflammation; however, the effects do not last indefinitely. Your doctor may recommend limiting the number of injections to three or four per year, per joint, due to possible side effects.
  • In some cases, pain and swelling may" flare" immediately after the injection, and the potential exists for long-term joint damage or infection. With frequent repeated injections, or injections over an extended period of time, joint damage can actually increase rather than decrease.
  • Disease-modifying anti-rheumatic drugs (dmards) are used to slow the progression of rheumatoid arthritis. Drugs like methotrexate, sulfasalazine, and hydroxychloroquine are commonly prescribed.
  • In addition, biologic dmards like etanercept (embril) and adalimumab (humira) may reduce the body's overactive immune response. Because there are many different drugs today for rheumatoid arthritis, a rheumatology specialist is often required to effectively manage medications.
  • Viscosupplementation involves injecting substances into the joint to improve the quality of the joint fluid.
  •  Glucosamine and chondroitin sulfate, substances found naturally in joint cartilage, can be taken as dietary supplements. Although patient reports indicate that these supplements may relieve pain, there is no evidence to support the use of glucosamine and chondroitin sulfate to decrease or reverse the progression of arthritis.
5 people found this helpful

7 Non Surgical Treatments For Shoulder Arthritis!

DNB (Orthopedics), MS - Orthopaedics
Orthopedist, Visakhapatnam
7 Non Surgical Treatments For Shoulder Arthritis!

The shoulders are the most mobile joints in your body. Shoulder joints undergo wear and a tear over time and hence become unstable. Shoulder arthritis is one of the painful conditions affecting the shoulder joints. Arthritis not only takes a toll on the tendons and muscles, but also affects the ligaments and joints too. They usually cause symptoms such as joint pain, resulting in limited mobility.


Nonsurgical or Lifestyle treatments:

  1. Take rest or avoid the activities that provoke pain or change the way of your arm movements.
  2. Physical therapy boosts shoulder mobility.
  3. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or aspirin alleviate pain and inflammation.
  4. Corticosteroid injections in the shoulders can also help to ease the pain and inflammation, although temporarily.
  5. Applying moist heat or ice packs over the shoulders for about half an hour at least thrice a day brings relief.
  6. Drugs such as methotrexate can be administered in case one is suffering from rheumatoid arthritis (a chronic disease attacking multiple joints of the body).
  7. Dietary supplements such as chondroitin and glucosamine may help reduce pain.

Surgical treatments (if your pain results in disability and does not lessen with nonsurgical options)

  1. Join replacement surgery or arthroplasty involves replacing the damaged parts of the shoulder with a prosthetic (artificial) joint.
  2. Few mild forms of arthritis may be treated using the Arthroscopic procedure (minimally invasive surgery). It requires a surgeon to ease the joint pain by making small incisions to “clean out” the joint. A tiny camera fitted into the joint guides the surgeon through the surgery.
  3. Resection arthroplasty is a method that involves the surgical removal of the bone from the collar bone and substituting it with a scar tissue to treat arthritis of particular joints. If you wish to discuss about any specific problem, you can consult an orthopedist. In case you have a concern or query you can always consult an expert & get answers to your questions!
2797 people found this helpful

Table of Content

About Dserin Gm 50 Mg/750 Mg Tablet
When is Dserin Gm 50 Mg/750 Mg Tablet prescribed?
What are the side effects of Dserin Gm 50 Mg/750 Mg Tablet ?
Key highlights of Dserin Gm 50 Mg/750 Mg Tablet