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Overview

Donep-M Tablet

Manufacturer :  Alkem Laboratories Ltd
Medicine Composition :  Donepezil, Memantine
Prescription vs OTC : Prescription by Doctor not required

About Donep-M Tablet

This medication is a cholinesterase inhibitor. It is used to treat a brain disorder that affects the ability to remember, communicate, think clearly. Also, it performs daily activities and may cause changes in mood and personality in people who have Alzheimer's disease. This medication improves mental function by increasing the number of certain chemicals in the brain.

However, it does not cure Alzheimer’s disease completely. Possible side effects of this medicine include loss of appetite, difficulty sleeping, gastrointestinal upset, vomiting, diarrhea or muscle cramping.

This medication comes as a tablet and a disintegrating tablet to take by mouth. It is usually taken once a day with or without food, in the evening before bedtime. Your doctor may prescribe to you a low dose initially to decrease the risk of side effects and gradually increase your dose after 4 to 6 weeks. Your doctor may increase your dose again 3 or more months later.

    What are the uses of Donep-M Tablet

    What are the contraindications of Donep-M Tablet ?

    What are the side effects of Donep-M Tablet ?

    Key highlights of Donep-M Tablet

    • How long is the duration of effect?

      The effect of this medication lasts for an average duration of 7 to 8 days.

    • What is the onset of action?

      The time taken to reach peak concentration is 3 to 4 hours.

    • Are there any pregnancy warnings?

      This medication is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medication.

    • Is it habit forming?

      No habit forming tendency has been reported

    • Are there any breast-feeding warnings?

      It is not known whether this medicine is excreted in breast milk. It is not recommended in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

    What are the substitutes for Donep-M Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Donep-M Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    How does this medication work?

    This medication is cholinesterase inhibitors. It works by increasing the cholinergic function by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase.

      What are the interactions of Donep-M Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Carvedilol

        These medicines may lower the heart rate and blood pressure if taken together. Inform the doctor if you are receiving antihypertensives like carvedilol, metoprolol, and nifedipine. Any symptoms of dizziness, irregular heartbeat should be informed to the doctor. Dose adjustment or an alternate medicine should be considered based on the clinical condition.

        Oxcarbazepine

        Inform the doctor if you are receiving oxcarbazepine, carbamazepine as these medicines will decrease the effect of this medication. Any symptoms of worsening of the condition should be reported to the doctor. Dose adjustments are to be made based on the clinical condition.

        Tramadol

        These medicines may increase the risk of seizures if taken together. The risk is more in the elderly population with a history of head injury or seizures. Any symptoms of seizures should be informed to the doctor. The dose of either of the medicines should be adjusted based on the clinical condition.
      • Interaction with Disease

        Bradycardia

        This medication is not recommended in patients with existing heart disease. An alternate medicine should be considered based on the clinical condition.

        Lung Disease

        This medicine is not recommended in patients with lung disorders like asthma or COPD. Inform the doctor if you have any symptoms of breathing difficulty. An alternate medicine should be considered based on the clinical condition
      • Interaction with Food

        Food

        Information not available.

      FAQs about Donep-M Tablet

      • Ques : What is Donep-M Tablet?

        Ans : This medication has Donepezil and Memantine as active ingredients present. It performs its action by increasing the growth of acetylcholine levels in the brain. Donep m is also used to avoid Memory disorders and Mental confusions.

      • Ques : What are the uses of Donep-M Tablet?

        Ans : This medication is used for the treatment and prevention from conditions and symptoms of diseases like severe Alzheimer's, forgetfulness Impaired reasoning, memory disorders, and mental confusions.

      • Ques : What are the Side Effects of Donep-M Tablet?

        Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of this medication. These include abnormal gait, heart failure, headache, vomiting, pancreas inflammation, tiredness, breathlessness and biliousness.

      • Ques : What are the instructions for storage and disposal Donep-M Tablet?

        Ans : This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of donep m.

      • Ques : Should I use Donep-M Tablet empty stomach, before food or after food?

        Ans : This medication is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

      • Ques : How long do I need to use Donep-M Tablet before I see improvement of my conditions?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

      • Ques : Is there any food or drink I need to avoid?

        Ans : The diet should be normal, there is nothing as such to avoid. However, eating healthy, doing physical exercises and avoiding any kind of harmful practice like smoking or drinking can uplift your health.

      • Ques : Will Donep-M Tablet be more effective if taken in more than recommended dose?

        Ans : There is no need to take this medication more than its recommended doses. Taking overdosage of this medication may trigger side effects. If the severity of the condition is not reducing with the recommended doses, then consult your doctor for re-examining your condition.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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