Dexomet 0.25% W/W Cream
Dexomet 0.25% W/W Cream essentially treats nerve pain like trigeminal neuralgia as well as diabetic neuropathy. Moreover, the drug also effectively treats bipolar disorder. Dexomet 0.25% W/W Cream functions as an anticonvulsant and decreases the occurrence of abnormal nerve impulses in the brain which can lead to severe reactions like seizures and acute pain.
The effect of the medicine is quite slow and does lead to some side effects; it may take about a couple of weeks or more for your condition to improve. The medicine should be taken as prescribed, as directions of the doctor should be adhered to strictly.
Before starting the drug make sure to give your doctor detailed information about any existing health issues and allergies. Before taking this medication to inform the doctor, if you are or suffer from:
- Heart problems
- Thyroid issues
- Mental illness
- Kidney problem
- Pregnant or going to become pregnant
If you are on the drug during your pregnancy make sure to clearly follow the doctor’s instructions on dosage and consumption. Do not stop the drug or increase dosage without the doctor’s advice as it can cause severe complications for the baby.
Symptoms of overdose include dizziness ataxia, drowsiness, nausea, vomiting, tremor, agitation, nystagmus, urinary retention, dysrhythmias, coma, seizures, twitches, respiratory depression, neuromuscular disturbances.
Provide general supportive care. Activated charcoal is effective at binding certain chemicals and this is especially true for carbamazepine; other treatment is supportive/symptomatic. Treatment consists of inducing emesis or gastric lavage.
EKG should also be monitored to detect cardiac dysfunction. Monitor blood pressure, body temperature, pupillary reflexes, bladder function for several days following ingestion.
Take exactly as directed (do not increase dose or frequency or discontinue without consulting prescriber). Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake).
The medication can treat the below provided problems:
Bone Marrow Suppression
A patient can suffer from the following side effects:
How long is the duration of effect?The effect of this medicine lasts for an average duration of 2 to 3 days
What is the onset of action?The peak effect of this medicine can be observed in 4.5 hours for immediate-release tablets.
Are there any pregnancy warnings?Crosses the placenta. Dysmorphic facial features, cranial defects, cardiac defects, spina bifida, IUGR, and multiple other malformations reported. Epilepsy itself, number of medications, genetic factors, or a combination of these probably influence the teratogenicity of anticonvulsant therapy. Benefit:risk ratio usually favors continued use during pregnancy,
Is it habit forming?No habit forming tendency has been reported.
Are there any breast-feeding warnings?This medicine crosses into breast milk. American Academy of Pediatrics considers compatible with breast-feeding.
Is It safe with alcohol?It is found to be unsafe when taken with alcohol.
Is it safe to drive while on this medicine?It might cause side effects that could affect the alertness of the patient. Hence affect the ability of the patient. If the patient is taking this medicine, driving must be avoided.
Does this affect kidney function?Limited data is available. Adjustment of dose may not be needed. Kindly consult your doctor before taking this medication.
Does this affect liver function?Caution must be taken in patients with liver disease. Dose adjustment might be needed. Kindly consult your doctor before taking this medicine.
Missed Dose instructionsIf you miss a dose of Dexomet 0.25% W/W Cream, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose instructionsSeek emergency medical treatment or contact the doctor in case of an overdose.
This medication belongs to the class anticonvulsant. It works by reducing the excitation of the brain cells by inhibiting the sodium channels thus inhibits the repetitive firing of brain cells.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
AlcoholConsumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
Interaction with Medicine
- Dexomet 0.25% W/W Cream may induce the metabolism of benzodiazepines, citalopram, clozapine, corticosteroids, cyclosporine, doxycycline, ethosuximide, felbamate, felodipine, haloperidol, mebendazole, methadone, oral contraceptives, phenytoin, tacrolimus, theophylline, thyroid hormones, tricyclic antidepressants, valproic acid, warfarin; monitor for altered response; dose adjustment may be needed.
- Cimetidine, clarithromycin, danazol, diltiazem, erythromycin, felbamate, fluoxetine, fluvoxamine, isoniazid, lamotrigine, metronidazole, propoxyphene, verapamil, fluconazole, itraconazole, and ketoconazole may inhibit hepatic metabolism of Dexomet 0.25% W/W Cream with resultant increase of carbamazepine serum concentrations and toxicity.
- CBZ may enhance hepatotoxic potential of acetaminophen.
- Neurotoxicity may result in patients receiving lithium and CBZ concurrently.
- Dexomet 0.25% W/W Cream is incompatible with chlorpromazine solution and thioridazine liquid. Schedule Dexomet 0.25% W/W Cream at least 1-2 hours apart from other liquid medicinals.
Interaction with Disease
DepressionThis medication should be given with caution in the patients with depression and suicidal thoughts. Frequent monitoring of depression symptoms is necessary. Dose adjustments are to be made based on the outcomes in the patient.liver disease. Frequent monitoring of liver function tests is necessary. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
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Ques: Can the use of Dexomet 0.25% W/W Cream lead to weight gain? If yes, how can it be managed?
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Ques: I am taking Dexomet 0.25% W/W Cream for trigeminal neuralgia. For how long do I need to take it?
Ques: How can I reduce the side effects of Dexomet 0.25% W/W Cream?
Dexamethasone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 27 May 2022].Available from:https://druginfo.nlm.nih.gov/drugportal/name/dexamethasone
Dexamethasone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 27 May 2022].Available from:https://go.drugbank.com/drugs/DB01234
Dexamethasone drop,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 27 May 2022].Available from:https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Dexamethasone
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