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Overview

Augmentin 625 Duo Tablet

Manufacturer :  Glaxo SmithKline Pharmaceuticals Ltd
Medicine Composition :  Amoxycillin, Potassium Clavulanate
Prescription vs OTC : Prescription by Doctor not required

About Augmentin 625 Duo Tablet

Augmentin 625 Duo Tablet is prescribed for the treatment of otitis media, sinusitis, and infections caused by susceptible organisms involving the lower respiratory tract, skin and skin structure, and urinary tract.

This is a combination medication that has Amoxycillin and Potassium Clavulanate as active ingredients. Its spectrum is the same as amoxicillin with additional coverage of beta-lactamase.

The extended coverage Augmentin 625 Duo Tablet is due to its combination, which makes it a useful alternative when amoxicillin resistance is present and patients cannot tolerate alternative treatments.

It is an antibiotic belonging to the class of penicillin antibiotic that helps in the treatment of bacterial infections. The medicine works against the synthesis of the bacteria. Augmentin 625 Duo Tablet also treats conditions like gonorrhoea, tonsillitis, infection in the eye, middle ear or nose.

It is important that you do not consume this tablet for cold, flu or other viral infections. Symptoms of penicillin overdose include neuromuscular hypersensitivity (agitation, hallucinations, asterixis, encephalopathy, confusion, and seizures) and electrolyte imbalance with potassium or sodium salts, especially in renal failure.

Hemodialysis may be helpful to aid in the removal of the drug from the blood, otherwise most treatment is supportive or symptom directed.

Take entire prescription, even if you are feeling better. Take at equal intervals around-the-clock; may be taken with milk, juice, or food. You may experience nausea or vomiting (small frequent meals, frequent mouth care, sucking lozenges, or chewing gum may help).

If using oral contraceptives, use additional contraceptive measures; amoxicillin may reduce the effectiveness of your oral contraceptive. Report rash; unusual diarrhoea; vaginal itching, burning, or pain; unresolved vomiting or constipation; fever or chills; unusual bruising or bleeding; or if the condition being treated worsens or does not improve by the time prescription is completed.

    What are the uses of Augmentin 625 Duo Tablet

    What are the contraindications of Augmentin 625 Duo Tablet ?

    What are the side effects of Augmentin 625 Duo Tablet ?

    Key highlights of Augmentin 625 Duo Tablet

    • How long is the duration of effect?

      The effect of the medicine lasts for more than 12 hours and close to 20 hours in some cases.

    • What is the onset of action?

      Post the consumption of this medicine, you can observe its peak effectiveness within an hour or two.

    • Are there any pregnancy warnings?

      Pregnant women must not consider the use of this medicine unless specifically asked by the doctor.

    • Is it habit forming?

      There have been no reported cases of habit forming or addictiveness associated with this tablet.

    • Are there any breast-feeding warnings?

      This medicine is safe to use during breastfeeding. Any incidence of rashes on skin or diarrhea in the infant should be reported. It is advised to consult a doctor before taking this medicine.

    • Is It safe with alcohol?

      It is better not to consume alcohol while on medication as it can lead to some serious side effects.

    • Is it safe to drive while on this medicine?

      It is advisable that you avoid driving if you experience drowsiness, dizziness or fatigue while on medication. This can hamper your driving skills and affect your judgement as well.

    • Does this affect kidney function?

      If you suffer from kidney disorders, you should exercise extreme caution while using the drug. If severe kidney diseases affect you, you should avoid this medicine altogether, as it can lead to complications.

    • Does this affect liver function?

      Patients suffering from liver disease should try to avoid the medicine. However, if prescribed, the doctor may adjust the dosage to ensure that the drug do not adversely affect the organ. Furthermore, such patients should undergo tests to monitor liver functionality.

    What are the substitutes for Augmentin 625 Duo Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Augmentin 625 Duo Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose, you should take one as soon as you remember that you’ve missed the dose.

    • Are there any overdose instructions?

      One should contact the doctor immediately if an overdose is suspected.

    How does this medication work?

    This medicine is a Penicillin antibiotic and inhibits the transfer of a peptide group in the transpeptidation process. As a result, the bacterium is not able to build cell walls and is killed. And it also works as a beta-lactamase inhibitor by binding to beta-lactamase enzyme produced by bacterial cells, which in turn inhibits its enzymatic action and prevents beta-lactam antibiotics from being metabolized by the enzyme.

      What are the interactions of Augmentin 625 Duo Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        When taken with alcohol, this pill can increase the patients risk of developing stomach ulcers and bleeding.

      • Interaction with Medicine

        Augmentin 625 Duo Tablet can interact with certain medicines or supplements to cause severe side effects. You must discuss the medicines you currently are taking with the doctor so that he/she can prescribe your substitutes.
        • Doxycycline, methotrexate, warfarin, ethinylestradiol and live vaccines are some of the medicines that interact with this medication to cause adverse side effects.
        • Decreased effect: Efficacy of oral contraceptives may be reduced.
        • Increased effect: Disulfiram, probenecid may increase amoxicillin levels, increased effect of anticoagulants.
        • Increased toxicity: Allopurinol theoretically has an additive potential for amoxicillin rash.
      • Interaction with Disease

        In patients with renal impairment, doses and/or frequency of administration should be modified in response to the degree of renal impairment; high percentage of patients with infectious mononucleosis have developed rash during therapy; a low incidence of cross-allergy with cephalosporins exists; incidence of diarrhea is higher than with amoxicillin alone. Hepatic dysfunction, although rare, is more common in elderly and/or males, and occurs more frequently with prolonged treatment.
      • Interaction with Food

        Generally antibiotics are taken after meals. Therefore, the drug does not interact adversely with your foods. However, consult the physician to get a clearer idea about how and when to take the medicine. May mix with milk, formula, or juice.

      FAQs about Augmentin 625 Duo Tablet

      • Ques : What is Augmentin 625 duo tablet?

        Ans : Augmentin is a penicillin antibiotic and is used to treat bacterial infections. It inhibits the synthesis of the cell wall in a bacteria and stops it from growing. It contains Amoxycillin and Potassium Clavulanate as working ingredient. It is a prescription medicine.

      • Ques : What is Augmentin 625 duo tablet used for?

        Ans : Augmentin is used for the treatment and prevention from conditions and symptoms of diseases like an ear infection, nose infection, throat infection, lower respiratory tract infection and skin Infection.

      • Ques : What are the side effects of Augmentin 625 duo tablet?

        Ans : Side effects include nausea Or vomiting, vaginal itching, diarrhoea etc.

      • Ques : Can Augmentin cause allergic reaction?

        Ans : Yes, Augmentin can cause an allergic reaction and can lead to being harmful to patients with known allergy to penicillins. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use Augmentin 625 duo tablet before I see improvement of my conditions?

        Ans : This medication should be consumed till complete eradication of disease, so it is advised to use till the time directed by your doctor and moreover taking this medication longer than it was prescribed can also cause inadequate effect on the patient.

      • Ques : At what frequency do I need to use Augmentin 625 duo tablet ?

        Ans : This medication is generally consumed 3 to 4 times a day as the time interval upto which this medication has an impact is around 4 to 6 hours.

      • Ques : Should I use Augmentin 625 duo tablet empty stomach, before food or after food?

        Ans : This medication is common to consume orally and the salts involved in the medication react properly if it is taken with the food, in order to reduce acidity and heartburn and taking it empty stomach may cause stomach upset as well.

      • Ques : What are the instructions for storage and disposal of Augmentin 625 duo tablet?

        Ans : This medication contains salts which are suitable to store at room temperature as keeping the medication above or below can cause inadequate effect.

      References

      • AUGMENTIN- amoxicillin and clavulanate potassium tablet, film coated- Daily Med [Internet]. dailymed.nlm.nih.gov. 2016 [Cited 25 April 2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=174cc098-fe49-4f1a-87e2-601c7573f0db

      • Amoxicillin mixture with Clavulanate- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/amoxyclav

      • Co amoxiclav:Uses, Side Effects, Mechanism,Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 24 April 2019]. Available from:

        https://www.drugsbanks.com/co-amoxiclav/

      • Amoxicillin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/26787-78-0

      • Clavulanic Acid- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/clavulanic%20acid

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Utsav NandwanaMBBS Bachelor of Medicine and Bachelor of Surgery, MBBSGeneral Physician
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