Lybrate Logo
Get the App
For Doctors
Login/Sign-up
tab_logos
About
tab_logos
Feed
Overview

Allopurinol 100 MG Tablet

Manufacturer :  Unicure Remedies Pvt. Ltd
Medicine Composition :  Allopurinol
Prescription vs OTC : Prescription by Doctor required

About Allopurinol 100 MG Tablet

Allopurinol 100 MG Tablet is widely used in treatment of gout and kidney stones. It is also used to treat secondary hyperuricemia which may occur during treatment of tumors or leukemia, and to prevent recurrent calcium oxalate calculi. This medication works by blocking xanthine oxidase which reduces the amount of uric acid made by the body.

You should not take this drug if you are allergic to it. This medicine belongs to a class of drugs called xanthine oxidase inhibitors. Increased uric acid levels are the major cause for gout and kidney problems. Tell your doctor if:

The dosage of this medication will be based on your age, medical condition and your response to the treatment. At high dosages, it is a theoretical possibility that oxypurinol stones could be formed but no record of such occurrence in overdose exists.

The usual dose is 100mg, administered once everyday. It is advised to take this medicine after meals. Follow the instructions of your doctor carefully to ensure the medication is effective.

Take as directed. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake) to avoid possible adverse renal problems. While using this medication, do not use alcohol, other prescription or OTC medications, or vitamin substances without consulting prescriber.

You may experience drowsiness (use caution when driving or engaging in tasks requiring alertness until response to drug is known); nausea, vomiting, or heartburn (small frequent meals, frequent mouth care, chewing gum, or sucking lozenges may help); hair loss (reversible).

Report skin rash or lesions; painful urination or blood in urine or stool; unresolved nausea or vomiting; numbness of extremities; pain or irritation of the eyes; swelling of lips, mouth, or tongue; unusual fatigue; easy bruising or bleeding; yellowing of skin or eyes; or any change in color of urine or stool.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    What are the uses of Allopurinol 100 MG Tablet

    • Gout

    • Increased Blood Uric Acid

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    What are the contraindications of Allopurinol 100 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    What are the side effects of Allopurinol 100 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    Key highlights of Allopurinol 100 MG Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 24 hours.

    • What is the onset of action?

      The effect of this medicine can be observed in 2 to 3 days.

    • Are there any pregnancy warnings?

      Inadequate data available. Women who are pregnant must consult doctor before using this drug.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      In case of breastfeeding, consult your doctor as it is not recommended to these women.

    • Is It safe with alcohol?

      Consult your doctor before consuming alcohol.

    • Does this affect kidney function?

      Dose adjustment is needed in patients suffering from renal impairment.

    • Does this affect liver function?

      Dose adjustment is needed in patients suffering from hepatic impairment.

    • Is it safe to drive while on this medicine?

      Do not drive while consuming this medicine as it causes dizziness and drowsiness.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    What are the substitutes for Allopurinol 100 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Allopurinol 100 MG Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    Where is the Allopurinol 100 MG Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    How does this medication work?

    This medicine belongs to the class xanthine oxidase inhibitor. It works by inhibiting xanthine oxidase enzyme thus inhibits the conversion of hypoxanthine to xanthine to uric acid without affecting the enzymes involved in purine and pyrimidine synthesis.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

      What are the interactions of Allopurinol 100 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        Concomitant use of this medicine along with the following must be avoided due to increased toxicity includes:
        • Inhibits metabolism of azathioprine and mercaptopurine (reduce to 1/3 or 1/4 of usual dose).
        • Use with ampicillin or amoxicillin may increase the incidence of skin rash.
        • Urinary acidification with large amounts of vitamin C may increase kidney stone formation.
        • Thiazide diuretics enhance toxicity, monitor renal function; thiazide diuretics and captopril (possibly other ACE inhibitors) may increase risk of hypersensitivity.
        • Vidarabine neurotoxicity may be enhanced.
        • Cyclosporine levels may be increased.
        • Hepatic iron uptake may be increased with iron supplements.
        • Allopurinol prolongs half-life of oral anticoagulants; allopurinol increases serum half-life of theophylline; allopurinol may compete for excretion in renal tubule with chlorpropamide and increases chlorpropamide's serum half-life.
      • Interaction with Food

        It should be administered after meals with plenty of fluid
      • Interaction with Disease

        Do not use to treat asymptomatic hyperuricemia. Discontinue at first signs of rash; reduce dosage in renal insufficiency, reinstate with caution in patients who have had a previous mild allergic reaction, use with caution in children; monitor liver function and complete blood counts before initiating therapy and periodically during therapy, use with caution in patients taking diuretics concurrently. Risk of skin rash may be increased in patients receiving amoxicillin or ampicillin. The risk of hypersensitivity may be increased in patients receiving thiazides, and possibly ACE inhibitors.

      FAQs about Allopurinol 100 MG Tablet

      • Ques : What is Allopurinol 100 MG Tablet?

        Ans : It is widely used in treating gout and kidney stones.

      • Ques : How long do I need to use Allopurinol 100 MG Tablet before I see improvement in my condition?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 week. Please consult your doctor for the time period you need to use this medication.

      • Ques : At what frequency do I need to use Allopurinol 100 MG Tablet?

        Ans : This medication is generally used once or twice a day. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

      • Ques : Should I use Allopurinol 100 MG Tablet empty stomach, before food or after food?

        Ans : This medication is advised to be consumed orally. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

      • Ques : What are the instructions for the storage and disposal of Allopurinol 100 MG Tablet?

        Ans : It should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      • Ques : What is the appropriate amount of hydration with Allopurinol 100 MG Tablet?

        Ans : It is important to intake at least 2 liters of water while taking this medication for the increased urine output and prevention of kidney stones.

      • Ques : How does Allopurinol 100 MG Tablet interact in patients with a history of bone marrow suppression?

        Ans : Allopurinol 100 MG Tablet tends to decrease the production of blood cells which increases the risk of infection. Hence, a patient with bone marrow suppression should be closely monitored while taking this medication. Frequent tests should be done to notice the alteration in blood cells.

      • Ques : How is Allopurinol 100 MG Tablet administered?

        Ans : Allopurinol 100 MG Tablet can be administered orally as well as an injection.

      • Ques : How long does Allopurinol 100 MG Tablet take to treat gout?

        Ans : Allopurinol 100 MG Tablet may take up to 6 weeks or the effective treatment of gout. A patient may experience gout attacks in the first two weeks while taking medication.

      References

      • Allopurinol-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/allopurinol

      • Allopurinol-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00437

      • ALLOPURINOL Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ALLOPURINOL

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
      swan-banner
      Sponsored

      Popular Questions & Answers

      View All

      Are Zyloric & Febutaz same salt or different I ...

      related_content_doctor

      Dr. Pramod Kumar Sharma

      Endocrinologist

      They are eifferent medicines you can try fabutas if allergic to Zyloric but start with One forth ...

      Hi I am 48 years old alcoholic I am hypertensiv...

      related_content_doctor

      Dr. Nazia Saleem

      Homeopath

      Stop alcohol if you want to safe your life firstly. Take a very light diet gourd will help you in...

      Renal function test has done to me. Everything ...

      related_content_doctor

      Dr. Premananda

      Orthopedic Doctor

      If you do not have symptoms then no need of any medication. Asymptomatic hyperuricaemia below 9 m...

      My left leg muscles aches at different times. I...

      related_content_doctor

      Dr. Julie Mercy J David

      Physiotherapist

      If you have leg pain then you have to rule out the causes for having leg pain. First of all check...

      I have swelling in my ankle due to uric acid. I...

      related_content_doctor

      Dr. C S Hiremath

      Homeopath

      Dear lybrate-user ji, a high uric acid level, or hyperuricemia, is an excess of uric acid in your...

      Table of content

      Content Details
      Profile Image
      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
      Profile Image
      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
      chat_icon

      Ask a free question

      Get FREE multiple opinions from Doctors

      posted anonymously
      swan-banner