It is not related to smoking but drinking definitely increases weight which is related to irregular menses. Still you r likely to be suffering from pcod. Unless you reduce your weight menses r not going to come normal. Primary objective of your treatment is weight reduction and maintain normal BMI of 18-25. This will regularize the monthly cycles and also help you get pregnant. You can take Metformin to reduce weight. You don?t need to take any medicine till 3 months for the menses to come. Only after 3 months of missed menses you should take medicines like progesterone Tablet (Deviry 10 mg twice a day for 5 days) for getting menses. For reducing your weight you should have brisk walk or jogging for 4-5 km daily, high protein diet (fish, chicken, mutton without fat, pulses, mushrooms), low carbohydrate diet (avoid rice, chapatti, bread, poha, upma, idli, dosa, potato, sugar etc and can use bhakri instead) and low fat i. E. Less oil and preferably use rice bran oil.