சிப்ரோஃப்ளோக்சசின் 500 மிகி மாத்திரை (Ciprofloxacin 500 MG Tablet)

Ciprofloxacin 500 mg is an antibiotic used in the treatment for various bacterial infections such as bronchitis, pneumonia, gonococcal treatment and other numerous diseases caused by bacteria.

It belongs to a class of antibacterial drug called quinolone antibiotics. This medication is not recommended for viral infections such as common cold and flu. The elderly aged people are advised to see a doctor in case they want to start medication as it may cause some side effects such as tendonitis and tendon rupture.

The severe side effects of சிப்ரோஃப்ளோக்சசின் 500 மிகி மாத்திரை (Ciprofloxacin 500 MG Tablet) are that the patient may suffer from Diarrhoea, Abdominal Pain, Joint Pains and Fever with Chills (Cold Fever). Though this effective medicine is not recommended for Pregnant and Breastfeeding Mothers.

The drug should also be avoided if the person has an Allergic reaction to the active ingredients, muscular problems such as tendinitis or tendon rupture and myasthenia graves.

If the person has a history of central nervous system disorders they should be extremely cautious if they want to start medication. Patients suffering from colitis and QT prolongation should also be aware of the risk and factors that may have an adverse effect on them.

The other thing to keep in mind for people under this medication is to avoid dairy products and other food items that are rich in calcium. They should keep a minimum gap of 2 hours before they consume the other.

• பாக்டீரியா தொற்றுகள் (Bacterial Infections)

• குறைந்த சுவாச பாதை தொற்று (Lower Respiratory Tract Infection)

• தோல் மற்றும் கட்டமைப்பு தொற்று (Skin And Structure Infection)

• எலும்பு மற்றும் மூட்டு நோய்த்தொற்றுகள் (Bone And Joint Infections)

• சிறுநீர் பாதை நோய்த்தொற்றுகள் (Infections Of Urinary Tract)

• இதய நோய்கள் (Heart Diseases)

• ஹைப்பர்சென்ஸ்டிவிட்டி (Hypersensitivity)

• குமட்டல் (Nausea)

• வாந்தி (Vomiting)

• பசியிழப்பு (Loss Of Appetite)

• வயிற்றுப்போக்கு (Diarrhoea)

• வயிற்று வலி (Abdominal Pain)

• தலைவலி (Headache)

• ஓய்வின்மை (Restlessness)

• சொறி (Rash)

• தலைச்சுற்றல் (Dizziness)

• குழப்பம் (Confusion)

• திடீர் நோய்தாக்கம் (Seizures)

• இரத்த சோகை (Anemia)

• நடுக்கம் (Tremor)

• விளைவு எவ்வளவு நேரம் நீடிக்கும்?

  The effect of this medication generally lasts for upto 8-10 hours depending upon the patient.

• என்ன செயல்பாடு ஆரம்பமாக உள்ளது?

  The drug usually shows effect after 30 minutes of intake and the peak effect is felt after an hour of administration.

• ஏதேனும் கர்ப்பகால எச்சரிக்கைகள் உள்ளனவா?

  The drug is not advised for expecting mothers unless absolutely necessary.

• அது பழக்கத்தை உருவாக்குமா?

  No, the drug is not habit forming. But you should not exceed the prescribed amount of medication.

• ஏதேனும் தாய்ப்பாலூட்டுவதற்கான எச்சரிக்கைகள் உள்ளனவா?

  The drug passes onto breast milk and is not at all recommended for breast feeding mothers.

• இது மதுவுடன் எடுத்துக்கொள்ள பாதுகாப்பானதா?

  The drug is know to interact with alcohol and abates its effectiveness. Therefore the consumption of these substances together is not recommended.

• இந்த மருந்து எடுத்துக்கொள்ளும்போது வாகனம் ஓட்டுவது பாதுகாப்பானதா?

  Since, it’s been reported the drug causes drowsiness and nausea it is not recommended to drive while under the effect of the drug.

• இது சிறுநீரக செயல்பாட்டை பாதிக்குமா?

  Yes, it alters the functioning of the kidney in many ways.

• இது கல்லீரல் செயல்பாட்டை பாதிக்கும்?

  Yes, it alters the functioning of the liver and should be avoided by people suffering from liver diseases.

• தவறவிடப்பட்ட மருந்தெடுப்புக்கு ஏதேனும் அறிவுறுத்தல்கள் உள்ளனவா?

  The missed dose should be taken as soon as you remember it. If the next dose is near take the next dose, avoid taking double dose.

• மிகை மருந்தளிப்புக்கு ஏதேனும் அறிவுறுத்தல்கள் உள்ளனவா?

  If there is a case of overdose contact the nearest medical emergency as it may prove to be fatal.

சிப்ரோஃப்ளோக்சசின் 500 மிகி மாத்திரை (Ciprofloxacin 500 MG Tablet) belongs to the class fluoroquinolones. It works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

நீங்கள் ஒன்றுக்கும் மேற்பட்ட மருந்துகளை எடுத்துக்கொண்டால், அல்லது சில உணவுகள் அல்லது பானங்கள் உடன் அதை கலக்கும் போதெல்லாம், நீங்கள் மருந்து இடைவினை புரியும் ஆபத்தில் இருக்கிறீர்கள்.

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• Interaction with Alcohol

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  The drug does not react well with alcohol and may reduce the effectiveness of the drug.

• Interaction with Medicine

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  1. CYP1A2 enzyme inhibitor:

     • Enteral feedings may decrease plasma concentrations of ciprofloxacin probably by >30% inhibition of absorption. Ciprofloxacin should not be administered with enteral feedings.

       The feeding would need to be discontinued for 1-2 hours prior to and after ciprofloxacin administration. Nasogastric administration produces a greater loss of ciprofloxacin bioavailability than does nasoduodenal administration.

     • Decrease absorption of ciprofloxacin by greater than or equal to 90% if administered concurrently

       RECOMMENDATION: Administer ciprofloxacin 2 hours before dose OR administer ciprofloxacin at least 4 hours and preferably 6 hours after the dose of these agents OR change to an H2-antagonist or omeprazole

     • Decrease absorption of ciprofloxacin significantly if administered concurrently

       RECOMMENDATION: Administer ciprofloxacin 2 hours before dose OR administer ciprofloxacin at least 2 hours after the dose of these agents

  2. Increased toxicity:
     • Caffeine and theophylline CNS stimulation when concurrent with ciprofloxacin
     • Cyclosporine may increase serum creatinine levels

• Interaction with Disease

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  The drug does not interact well with people suffering from central nervous system disorders and must be extremely cautious in patients with history of seizures as it may worsen the patients condition. Patients who are suffering from colitis should also avoid this drug. Patients suffering from QT Prolongation and renal impairment should also avoid taking this drug.

• Interaction with Food

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  This drug does not interact well with food products that are rich in calcium especially dairy products and therefore a minimum gap of two hours should be maintained before the consumption of the other.