Zentel 400 MG Tablet

Created by GlaxoSmithKline Pharmaceuticals Ltd, Zentel comprises of Albendazole which is important for treating diseases due to an infestation of parasitic worms. It is an anti-parasitic medicine which treats infections caused by tapeworms like hydatid disease and neurocysticercosis which adversely affects the brain and muscles.

Diseases such as pinworm disease, giardiasis, hydatid disease (intestinal infection), neurocysticercosis (affecting brain and muscles), ascariasis (gastrointestinal infection), and filariasis (affecting the lymph nodes). This medicine falls under a category of medicines called anthelmintic which eradicates parasites and worms by stunning them and destroying them with minimal harm caused to the body.

Cytoplasmic microtubules and tegmental cells are degenerated by the sulfoxide compound of the medicine. This causes the energy present in the parasite to get depleted along with the destruction of metabolic processes which eventually kills the parasites. It has been advised that the medicine should be consumed on an empty stomach or after a meal in special cases. The tablet must not be crushed or chewed but swallowed with water at once.

Zentel is also recommended by the doctor with other drugs for the treatment of some conditions such as corticosteroids which help in preventing additional pressure on the skull while undergoing the first week of treatment. The patients who are acutely allergic to Albendazole and Benzimidazoles and the patient must revert to the doctor immediately for timely treatment.

Below are the conditions for which this medicine is used:

• Hydatid Disease

• Neurocysticercosis

• Enterobiasis

• Strongyloidiasis

• Ascariasis

• Trichuriasis

• Filariasis

• Giardiasis

• Allergy

Some of the side effects that may be observed in patients are:

• Stomach Pain

• Nausea

• Vomiting

• Rash

• Urticaria

• Alopecia

• Altered Liver Function Test

• Allergic Reaction

• How long is the duration of effect?

  The effect of Zentel is used for treating parasitic infections last for more than 8-9 hours after it is broken down by the liver.

• What is the onset of action?

  Within 2-5 hours of administration, the peak level of tablet performance can be built as it is not absorbed from the gastrointestinal tracts.

• Are there any pregnancy warnings?

  The growing fetus which is slowly developing in the patient’s body can be adversely affected by the consumption of Zentel. There have been no conclusive studies when it comes to humans, which is why Zentel is not recommended for pregnant women.

• Is it habit forming?

  Zentel tablet doesn’t have any habit forming tendencies.

• Are there any breast-feeding warnings?

  Zentelmust not be used by breastfeeding women until it has been deemed as absolutely necessary. The doctor must be notified before the medicine is consumed.

• Is it safe to drive while on this medicine?

  Zentel can cause drowsiness in the patient, which can be very dangerous while driving. The patient must refrain from performing any activity that requires alertness in the patient.

• Does this affect kidney function?

  For patients suffering from any kidney abnormalities, the consumption of Zentel can cause kidney disorders such as kidney failure. Consulting the doctor before consumption is a prudent idea.

• Does this affect liver function?

  Patients that have a history of liver impairment can end up facing adverse effects as liver enzymes increase above a certain threshold.

Below is the list of medicines, which have the same composition, strength and form as Zentel 400 MG Tablet , and hence can be used as its substitute.

• Milibend 400 MG Tablet

  Glenmark Pharmaceuticals Ltd

• Lupibend 400 MG Tablet

  Lupin Ltd

• Noworm 400 MG Tablet

  Alkem Laboratories Ltd

• Banhelmin 400 MG Tablet

  Orchid Chemicals & Pharmaceuticals Ltd

• Alminth 400 MG Tablet

  Torrent Pharmaceuticals Ltd

• Are there any missed dose instructions?

  The patient must take the missed dose as soon as possible and skip the dose if the time for the next dose as scheduled occurs.

• Are there any overdose instructions?

  Consult your doctor before using this medication.

This drug gets converted into sulfoxide form and causes degeneration of cytoplasmic microtubules and tegmental cells. This results in depletion of energy and metabolic processes and the parasites are killed

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Alcohol

  The interaction of Zentel with alcohol is unknown which is why it is advisable to consult the doctor for such as case.

• Interaction with Medicine

  Zentel reacts severely with medicines that contain Clozapine compounds. It has moderate reactions with Carbamazepine, Dexamethasone, Phenytoin, and Praziquantel compounds.

• Interaction with Disease

  Zentel has the ability to tamper with the functionality of the bone marrow and reduce the count of white blood cells. It can cause bone marrow suppression.

• Interaction with Food

  Zentel must not be consumed with grapefruit juice while the treatment is going on as it can lead to many adverse effects. The medicine must be consumed with food so that it can spread throughout the body.