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Zentel 400 MG Tablet

Manufacturer: Glaxosmithkline Pharmaceuticals Ltd
Medicine composition: Albendazole
Prescription vs.OTC: Prescription by Doctor not required
Last Updated: June 17, 2019

Created by Glaxosmithkline Pharmaceuticals Ltd, Zentel 400 MG tablet comprises of Albendazole which is important for treating diseases due to an infestation of parasitic worms. It is an anti-parasitic medicine which treats infections caused by tapeworms like hydatid disease and neurocysticercosis which adversely affects the brain and muscles. Diseases such as pinworm disease, giardiasis, hydatid disease (intestinal infection), neurocysticercosis (affecting brain and muscles), ascariasis (gastrointestinal infection), and filariasis (affecting the lymph nodes).

This medicine falls under a category of medicines called anthelmintic which eradicates parasites and worms by stunning them and destroying them with minimal harm caused to the body. Cytoplasmic microtubules and tegmental cells are degenerated by the sulfoxide compound of the medicine. This causes the energy present in the parasite to get depleted along with destruction of metabolic processes which eventually kills the parasites.

It has been advised that the medicine should be consumed on an empty stomach or after a meal in special cases. The tablet must not be crushed or chewed but swallowed with water at once. Zentel is also recommended by the doctor with other drugs for treatment of some conditions such as corticosteroids which help in preventing additional pressure on the skull while undergoing the first week of treatment. The patients who are acutely allergic to Albendazole and Benzimidazoles and the patient must revert to the doctor immediately for timely treatment.

  • headache

  • Seizures

  • Darker Urine

  • Temporary Hair Loss

  • Allergic skin reaction

  • Blood Reactions

  • Jaundice

  • Neutropenia

  • How long is the duration of effect?

    The effect of Zentel 400 Mg which is used for treating parasitic infections last for more than 8-9 hours after it is broken down by the liver.

  • What is the onset of action?

    Within 2-5 hours of administration, the peak level of tablet performance can be built as it is not absorbed from the gastrointestinal tracts.

  • Are there any pregnancy warnings?

    The growing fetus which is slowly developing in the patient’s body can be adversely affected by the consumption of Zentel. There have been no conclusive studies when it comes to humans, which is why Zentel is not recommended for pregnant women.

  • Is it habit forming?

    Zentel 400 MG tablet doesn’t have any habit forming tendencies.

  • Are there any breast-feeding warnings?

    Zentel 400 MG must not be used by breastfeeding women until it has been deemed as absolutely necessary. The doctor must be notified before the medicine is consumed.

  • Is it safe to drive while on this medicine?

    Zentel can cause drowsiness in the patient, which can be very dangerous while driving. The patient must refrain from performing any activity that requires alertness in the patient.

  • Does this affect kidney function?

    For patients suffering from any kidney abnormalities, the consumption of Zentel can cause kidney disorders such as kidney failure. Consulting the doctor before consumption is a prudent idea.

  • Does this affect liver function?

    Patients that have a history of liver impairment can end up facing adverse effects as liver enzymes increase above a certain threshold.

Below is the list of medicines, which have the same composition, strength and form as Zentel 400 MG Tablet , and hence can be used as its substitute.

  • Are there any missed dose instructions?

    The patient must take the missed dose as soon as possible and skip the dose if the time for the next dose as scheduled occurs.

  • Are there any overdose instructions?

    Overdose symptoms that are visible include fainting, confusion, and difficulty in breathing. The doctor must be consulted immediately and medical attention must be provided as soon as possible.

Zentel 400 MG Tablet gets converted into sulfoxide form and causes degeneration of cytoplasmic microtubules and tegmental cells. This results in depletion of energy and metabolic processes and the parasites are killed

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Disease

    Zentel 400 MG has the ability to tamper with the functionality of the bone marrow and reduce the count of white blood cells. It can cause bone marrow suppression. The medicine also affects people with a history of eye diseases such as retinal lesions and can cause retinal damage.

  • Interaction with Alcohol

    The interaction of Zentel 400 MG with alcohol is unknown which is why it is advisable to consult the doctor for such as case.

  • Interaction with Food

    Zentel 400 MG must not be consumed with grapefruit juice while the treatment is going on as it can lead to many adverse effects. The medicine must be consumed with food so that it can spread throughout the body.

  • Interaction with Medicine

    Zentel 400 MG reacts severely with medicines that contain Clozapine compounds. It has moderate reactions with Carbamazepine, Dexamethasone, Phenytoin, and Praziquantel compounds.

Ques: What is Zentel 400 mg tablet?

Ans: Zentel 400 mg is a prescription medicine which belongs to a class of drugs known as Anthelmintic. These are a class of antiparasitic medications that treat patients who have a symptoms known helminthiasis. These medicines remove parasitic worms (helminths) and other internal parasites from the body by killing the parasites such as roundworms, flukes, and tapeworms.

Ques: What is Zentel 400 mg tablet used for?

Ans: Zentel 400 mg tablet is a medication which is used to treat, control, and prevent below mentioned conditions such as: Whipworm infections, Hydatid Disease, Giardiasis, Neurocysticercosis, Hookworm infections, Pinworm infections, Filarial worm infections, Parasitic Intestinal infections, Enterobiasis, Ascariasis, Cutaneous Larva Migrans, Filariasis, Strongyloidiasis, Trichuriasis, Tapeworm infections, Threadworm infections and Roundworm infections.

Ques: What are the side effects of Zentel 400 mg tablet?

Ans: Zentel 400 mg tablet is a medication which has known side effects. Consult your doctor first before taking this medication. These side effects may or may not appear always and some of them are rare but severe. If you experience any of the below mentioned side effects, contact your doctor immediately. Here are some side effects of Zentel 400 mg tablet: Reversible loss of hair, Stomach pain, Vertigo, Vomiting, Fever, Headache, Increased level of liver enzymes, Increased pressure inside the brain, Nausea, Dizziness, Lack of energy, Diarrhea and Blurred vision.

Ques: When should i take Zentel 400 mg tablet?

Ans: Zentel 400 mg tablet is a medication which should usually be taken on an empty stomach. In some conditions the medicine should to be taken after meal. It is a prescribed medication which should only be taken on a prescription. Zentel 400 mg tablet can not be crushed or chewed. It should be swallowed whole at once.

Ques: Is Zentel an antibiotic?

Ans: Yes. Zentel is an antibiotic medication.

Ques: How does Zentel work?

Ans: Zentel is a medication that works by controlling worms to absorb sugar. It helps in maintaining the level of energy and treat infections.

Ques: Can I take Zentel with fluconazole?

Ans: Yes, Zentel can be taken with fluconazole altogether.

Ques: Is Zentel effective for treating pinworms?

Ans: Yes, Zentel is an effective medication that is used to treat pinworms.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Pharmacology
Reviewed By
MD-Pharmacology, MBBS
Sexology
Table of Content
About Zentel 400 MG Tablet
What are the uses of Zentel 400 MG Tablet
What are the contraindications of Zentel 400 MG Tablet ?
What are the side effects of Zentel 400 MG Tablet ?
Key highlights of Zentel 400 MG Tablet
What are the substitutes for Zentel 400 MG Tablet ?
What are the dosage instructions?
How does medicine works?
What are the interactions of Zentel 400 MG Tablet ?
Zentel 400 MG Tablet Frequently Asked Questions (FAQs):