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Tugain 10% Solution

Manufacturer :  Cipla Ltd
Medicine Composition :  Minoxidil
Prescription vs OTC : Prescription by Doctor required

About Tugain 10% Solution

Tugain 10% Solution is primarily used in the treatment of hair growth and male pattern baldness. It doesn't affect receding hairline and baldness at the front part of the scalp. About 2 percent of this medication is used in women who have the problem with thinning hair. It needs to be applied topically on the skin.

It falls under the category of drugs known as vasodilators. Thus when taken orally, it is also used as an antihypertensive and even prescribed to treat patients with high blood pressure.

Before using this Tugain 10% Solution you should notify your doctor if you have or are:

  • Allergic to it or any other drugs, foods or substances.
  • Taking any prescription or non-prescription drugs, herbal medications or dietary supplements.
  • Pregnant, or are planning to become pregnant, or are breastfeeding a baby.
  • Involved in activities that cause extreme sunlight exposure. It may bring about skin sensitivity.
  • Heart, kidney, liver or any scalp related diseases.

This medication is sold as both prescription or non-prescription medicine for the treatment of alopecia. It is also available in both tablet and liquid form. Application entails you to apply it on your scalp twice a day.

You should apply it as much as it is prescribed by your doctor or as written on the label. Visible results will only start to show after at least four months of usage.

Symptoms of overdose include hypotension, tachycardia, headache, nausea, dizziness, weakness syncope, warm flushed skin and palpitations; lethargy and ataxia may occur in children.

Hypotension usually responds to I.V. fluids, Trendelenburg positioning or vasoconstrictor; treatment is primarily supportive and symptomatic. Topical product must be used every day. Hair growth usually takes 4 months.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the uses of Tugain 10% Solution

    • Alopecia

    • Hypertension

      Management of severe hypertension (usually in combination with a diuretic and beta-blocker)

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the contraindications of Tugain 10% Solution ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the side effects of Tugain 10% Solution ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Key highlights of Tugain 10% Solution

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 1 to 5 days.

    • What is the onset of action?

      The effect of this medicine can be observed in 1 hour after an oral dose and 4 to 5 hours after topical application.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is known to excreted through breast milk. This medicine is not recommended for breastfeeding women.

    • Is It safe with alcohol?

      Avoid drinking alcohol. Consumption of alcohol is not recommended.

    • Is it safe to drive while on this medicine?

      This medication may affect the consciousness of the patient. Avoid driving or using any heavy operating machine.

    • Does this affect kidney function?

      This medicine is found to be safe to use in patients with renal impairment. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      Limited information is available regarding its use in patient with liver disease. Kindly consult your doctor before taking this medication.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the substitutes for Tugain 10% Solution ?

    Below is the list of medicines, which have the same composition, strength and form as Tugain 10% Solution , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Where is the Tugain 10% Solution approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    How does this medication work?

    This medication is a vasodilator. It works by opening the potassium channels, causes hyperpolarization and dilation of arterioles. This effect will relax the smooth muscle and reduces peripheral vascular resistance, thus reduces the blood pressure. It stimulates the hair growth by prolonging the anagen phase of the hair growth by promoting the survival of human dermal papillary cells (DPCs)

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

      What are the interactions of Tugain 10% Solution ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Medicine

        Alprazolam

        These medications may lower the blood pressure if taken together. Inform the doctor if you are receiving any central nervous system medication. Dose adjustments are to be made based on the clinical condition.

        Corticosteroids

        Corticosteroids like cortisone, dexamethasone, and prednisolone may reduce the effect of this medication. Inform the doctor if you are receiving any of these medications and report if any symptoms of uncontrolled blood pressure. Dose adjustments are to be made based on the clinical condition.

        Guanethidine

        These medications are not recommended together due to the risk of lowering the blood pressure. Any symptoms of change in the blood pressure should be informed to the doctor.
      • Interaction with Food

        Avoid natural licorice (causes sodium and water retention and increases potassium loss).
      • Interaction with Disease

        • Maximum therapeutic doses of a diuretic and two antihypertensives should be used before this drug is ever added. It can cause pericardial effusion, tamponade, or exacerbate angina pectoris.
        • Monitor patients who are receiving guanethidine concurrently (orthostasis can be problematic). May need to add a diuretic to minimize fluid gain and a beta-blocker (if no contraindications) to treat tachycardia.
        • Rapid control of blood pressure can lead to syncope, CVA, MI, ischemia.
        • Hypersensitivity reactions occur rarely.
        • Avoid use for a month after acute MI.
        • Inform patients of hair growth patterns before initiating therapy.
        • May take 1-6 months for hypertrichosis to reverse itself after discontinuation of the drug.
        • Use with caution in patients with pulmonary hypertension, significant renal failure, CHF, or ischemic disease.
        • Renal failure and dialysis patients may require a smaller dose.

      FAQs about Tugain 10% Solution

      • Ques : What is Tugain 10% Solution?

        Ans : This medication is used in the treatment of hair growth, male pattern baldness and hypertension.

      • Ques : How long do I need to use Tugain 10% Solution before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Tugain 10% Solution?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Tugain 10% Solution empty stomach, before food or after food?

        Ans : This medication can be taken before and after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Tugain 10% Solution?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : Can Tugain 10% Solution cause hair loss?

        Ans : Yes, it may cause hair loss. But, if it persists for more than 2 weeks, you should stop using Tugain 10% Solution and contact your doctor.

      • Ques : Is Tugain 10% Solution safe to use?

        Ans : Yes, this drug is safe if you use it as directed by your doctor. For best results, read all the directions before using it and follow them carefully.

      • Ques : Is the hair growth by Tugain 10% Solution treatment permanent?

        Ans : It is advised to continue applying this medication for continued hair growth. If you stop using this drug, the regrown hair may disappear after 3-4 months and balding or hair loss may restart.

      • Ques : Can Tugain 10% Solution cause weight gain?

        Ans : Yes, this drug can cause your weight to increase. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables, and fat-free products to manage your weight. You may also consult with a dietician to get a diet plan that suits you best.

      • Ques : How long does it take to see results with Tugain 10% Solution?

        Ans : Since hair growth is a slow process, it may take some time before you see new hair growth after starting the treatment with Tugain 10% Solution. You need to use Tugain 10% Solution for 4 months to see its effects.

      • Ques : Is Tugain 10% Solution safe to use on the face?

        Ans : No, you are advised not to apply this medication to any other body areas other than the scalp.

      • Ques : Do I need to wash my hair every day when using Tugain 10% Solution?

        Ans : No, it is not required to shampoo your hair every day before applying this drug.

      • Ques : How often should Tugain 10% Solution be applied?

        Ans : The general recommendation is that it should be used twice daily. Follow your doctor's instructions and take it in the dose and duration advised by your doctor.

      References

      • Minoxidil- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 10 December 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/minoxidil

      • Minoxidil- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 10 December 2019]. Available from:

        https://www.drugbank.ca/drugs/DB00350

      • Regaine for Men Extra Strength- EMC [Internet] medicines.org.uk. 2018 [Cited 10 December 2019]. Available from:

        https://www.medicines.org.uk/emc/product/103/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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