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Teriparatide

Prescription vs.OTC: Prescription by Doctor required

Teriparatide functions exactly like the hormone parathyroid, found naturally in the human body. Teriparatide is man-made, and helps increase the density of bones and make them stronger, in order to stop fractures.

The drug is used in the treatment of osteoporosis in both men and women. It may also be used in the treatment of other health conditions as determined by our doctor.

To avoid any complications when using Teriparatide, make sure to inform you medical practitioner about any allergies you have, or health problems like bone disorders, high calcium and phosphate levels in the body, hyperparathyroidism and kidney stones. Also provide him with a list of the different medicine that you are taking presently.

Take the dose that has been prescribed to you by your doctor. Do not tamper with the dosage, unless it is changed by your health care provider. The drug is given in the form of an injection either by a doctor or a nurse. One can even learn how to take the injection on their own.

Diarrhea, dizziness, heartburn, congestion, development of a hoarse voice, indigestion, changes in voice, runny nose, muscle cramp and pain etc. are some minor side effects of Teriparatide. A few major side effects include weakness, dry mouth, fainting spells, sweating, sore throat, problems with breathing and wheezing.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Orthopedist before using this medicine.

In addition to its intended effect, Teriparatide may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Limb pain

Fainting

Headache

Gastro-esophageal reflux disease

Breathlessness

Hypercholesterolaemia

Injection site pain

Increased sweating

Hiatus hernia

Decreased blood pressure.

Is It safe with alcohol?

Osteri 750mcg injection may cause excessive drowsiness and calmness with alcohol.

Are there any pregnancy warnings?

Osteri 750mcg injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Are there any breast-feeding warnings?

Unknown. Human and animal studies are not available. Please consult your doctor.

Is it safe to drive while on this medicine?

Patients may experience undesirable effects like orthostatic hypotension or dizziness and should avoid driving vehicles or using machines.

Does this affect kidney function?

Caution should be used in patients with moderate to severe renal impairment.

Does this affect liver function?

There is no data available. Please consult doctor before consuming the drug.

Are there any missed dose instructions?

If you miss a dose of Teriparatide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Below is the list of medicines, which contains Teriparatide as ingredient
Abbott India Ltd
Intas Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Sun Pharmaceutical Industries Ltd
Alkem Laboratories Ltd
Bharat Serums & Vaccines Ltd
LG Lifesciences
Emcure Pharmaceuticals Ltd
Corona Remedies Pvt Ltd
Teriparatide is a part of human parathyroid hormone (PTH), amino acid sequence 1 via 34 of complete molecule which comprises amino acid sequence 1 through 84. Endogenous PTH is the most important controller of phosphate and calcium metabolism within the kidney and the bone.
What are you using Teriparatide for?
Osteoporosis
density of bones
Other
How much was the improvement?
Excellent
Poor
Average
How long did it take before seeing improvement?
More than 2 days
Within 2 days
How frequently did you take this medicine?
Once a day
Not taking on daily level
How did you take this medicine?
With or without food
What were the side effects of this medicine?
Limb pain
Gastro-esophageal reflux disease
Dizziness
Headache
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I want to know that how the report is of my mother from MRI findings of L.S Spine using T1 trin corr, T1,T2 weighted axial. Findings-1) Decrease in body ht of L5, L4,L3, L2 and D12 vertebra and mild anterior wedging with out any significant f/o marrow edema s/o compression# 2) Mild retropulsion of body of D12 vertebra causes minimal anterior thecal sac compression. 3) Moderate to severe disc dessication are seen all lumbar IV disc and small interior marginal osteophytes are seen around L4/L5, L3/L4, L2/L1 iv disc. 4) annular bulging of L5/S1 and L4/L5 disc with mild central disc protrusion causes minimal compression of anterior thecal sac compression. 5) annular bulging of L3/L4 disc causes severe narrowing of b/l neural foreman and mild compression of anterior thecal sac compression. 6) Mild bulging of L2/L3 disc causes minimal effacement of anterior epidural space and mild narrowing of b/i neural foreman. Now the following tablets and injections is given by doctor. Medicines are ultracet, problem strong, Gabaneuron NT and Arachitol 6L vitamin D3 injection. Can any one suggest weather these symptoms will be corrected with medicine and injection. She is unable to wake up from bed and can't sleep properly. She feels severe pain in lower back.

MS(ORTHO), FNB (SPINE SURGERY)
Orthopedist, Kurnool
I want to know that how the report is of my mother from MRI findings of L.S Spine using T1 trin corr, T1,T2 weighted ...
MRI report is showing multiple osteoporotic vertebral fractures She should get investigated for bone mineral density testing and may benefit from bone formative agents like teriparatide If pain is more than months then we have to analyse the symptomatic fracture among all the vertbral fractures and proceed with The bone augmentation procedures.

In case of nonunion of femur fracture after 5-6 months of fixation with intramedullary nails n implant, what is further appropriate course of action (age 50)

Bachelor in Physiotherapy
Physiotherapist, Ghaziabad
In case of nonunion of femur fracture after 5-6 months of fixation with intramedullary nails n implant, what is furth...
Hi there There can be many factors responsible for non union of fracture like too large space for bony remodelling to bridge, Interposition of periosteum, muscle or cartilage, Bony site with limited or less blood supply and more. If fracture won't unite after 6 months it my be considered in as delayed or non union of fracture. These approaches can be effective after non union: Non-surgical approaches Early weight bearing and casting may be helpful for delayed union and non-union. Bone stimulation can sometimes be used. This delivers pulsed ultrasonic or electromagnetic waves to stimulate new bone formation. It needs to be used for up to an hour every day, and may take several weeks to be effective. Medical treatments such as teriparatide have also been used to promote fracture healing, particularly in patients with osteoporosis. Surgical approaches: Debridement to establish a healthy infection-free vascularity at the fracture site. Bone grafting to stimulate new callus formation. Bone may be taken from the patient or may be cadaveric. Bone graft substitutes/osteobiologics. Internal fixation to reduce and stabilise the fracture. Depending on the type of non-union, any combination of the above procedures.

Dr. Sir, I am diabetic patient and taking insulin injection. I am in Dubai, UAE and when I go to Andhra on vacation it takes around 12 hours to reach my native place. If I take Insulin injections without keeping in ice for 12 hours, will it spoil and becomes useless? Please reply. (Ahmed Ali)

Practical Course In Diabetology, Post Graduate Course In Diabetology, MBBS
Endocrinologist, Jammu
Dr. Sir, I am diabetic patient and taking insulin injection. I am in Dubai, UAE and when I go to Andhra on vacation i...
No it won't become useless. In fact vial or cartridge in use should be at room temperature.Nothing will happen upto one month.
1 person found this helpful

Hi, Please suggest Ayurvedic remedies for disturb PTH and calcitonin. I am taking limestone water 4 days ago and now I fell slow metabolism.

Bachelor of Naturopathy & Yogic Sciences (BNYS), M.sc in yoga and naturopathy, Bachelor of Ayurveda, Medicine and Surgery (BAMS), Bachelor of Physiotherapy
Ayurveda, Delhi
Hi, Please suggest Ayurvedic remedies for disturb PTH and calcitonin. I am taking limestone water 4 days ago and now ...
Hi Lybrate user, can you explain the range of calcitonin and pth? You can have milk, cheese, yogurt, soyabean, lentils Chickpeas, beans, Avoid amoking and alcohol Regular exercise Add nuts and seeds Restrict the amount of salt Soak almonds in water overnight and morning add milk to it and rake this on your empty stomach.

I am suffering from Kidney stones from last 5 years. Whenever pain appears in the body stones pass through urine usually in 3-4 days. Stones keep appearing in the body time and again. I am also avoiding certain foods after deep analysis of stone I sent to lab. Is there any permanent solution for this problem?

MS - General Surgery, MCh Urology
Urologist, Hyderabad
I am suffering from Kidney stones from last 5 years. Whenever pain appears in the body stones pass through urine usua...
Respected Sir 1.The estimated chance of recurrence of stone formation is nearly 50% at 5 years.(If you take 100 patients, 50 patients out of them will have stone recurrence in 5 years time) 2.Since you are a recurrent stone former, you need an extensive metabolic evaluation to know the cause of stone formation and recurrence. 3.A detailed history needs to be taken regarding underlying predisposing conditions, dietary excesses, inadequate fluid intake etc. 4.A basic metabolic panel (Blood urea, serum creatinine, serum uric acid, serum electrolytes) along with estimation of serum calcium and PTH needs to be done. 5.You have already got a stone analysis done which might give a clue regarding the composition of the stone. 6.Please Consult your urologist who would advice you proper evaluation. 7.Please follow the following precautions to prevent recurrent stone formation: a.Make sure you drink plenty of oral fluids ~ 2.5 to 3 litres / day b.Restrict excess salt intake and animal protein (red meat and fish) intake in the diet. C.Include plenty of fruits and vegetables in the diet. D.Avoid high oxalate containing foods like spinach, chocolates,nuts etc. E.Maintain a healthy physique and exercise regularly. Hope this helps Get Well soon Thanks.

Popular Health Tips

Who Is At Risk Of Osteoporosis?

DNB (Orthopedics), MS - Orthopaedics
Orthopedist, Visakhapatnam
Who Is At Risk Of Osteoporosis?

Osteoporosis is a condition which usually results due to a decrease in bone density. In this condition, the bones become weak and brittle. Fractures are a common result of osteoporosis. Usually, symptoms or signs do not show up until the condition progresses to its advanced stages.

Since osteoporosis is usually irreversible and incurable, preventing the fractures is considered to be extremely important.

Who is at risk of osteoporosis?
All men and women have some risk of developing 'thinning' of the bones (osteoporosis) as they become older, particularly over the age of 60. As mentioned above, women are more at risk than men. The following situations may also lead to excessive bone loss and so increase your risk of developing osteoporosis. If you:

  1. Are a woman who had the menopause before 45 years of age
  2. Have already had a bone fracture after a minor fall or bump
  3. Have a strong family history of osteoporosis.
  4. Have a body mass index (BMI) of 19 or less (that is, you are very underweight)
  5. Have irregular periods
  6. Have taken, or are taking, a steroid medicine (such as prednisolone) for three months or more
  7. Are a smoker
  8. Have an alcohol intake of more than four units per day
  9. Lack calcium and/or vitamin D (due to a poor diet and/or little exposure to sunlight).
  10. Are mostly inactive

Ways To Treat Osteporosis

Osteoporosis in women can be treated using Hormone Replacement Therapy (HRT). The therapy makes use of either a combination of progestin and oestrogen or simply, oestrogen. However, it is possible that certain combinations have side-effects that might give rise to other medical conditions. Therefore, proper consultation with an orthopedist is an essential pre-requisite so that the condition of osteoporosis as well the side effects may be addressed before proceeding with Hormone Replacement Therapy.

There are a number of medications that can be used which have long-term effects on osteoporosis. However, the schedule for intake of these medicines should be followed diligently. Failing to adhere to the schedule could lead to serious complications. For example, the intake of Risedronate medications (prevent bone loss) should be scheduled once every month, failing which can cause ulcers in the food pipe. Raloxifene has effects which are similar to oestrogen but does not exhibit any serious side effects. Teriparatide can be used to treat osteoporosis in people who have a high risk of suffering from bone fractures.

Don't rely entirely on medication as the only treatment for your osteoporosis. These practices also are important:

  1. Exercise. Weight-bearing physical activity and exercises that improve balance and posture can strengthen bones and reduce the chance of a fracture. The more active and fit you are as you age, the less likely you are to fall and break a bone.
  2. Good nutrition. Eat a healthy diet and make certain that you're getting enough calcium and vitamin D. Being underweight or losing a lot of weight unintentionally is associated with poorer bone health and a higher risk of fracture — even if you're taking a bisphosphonate.
  3. Quit smoking. Smoking cigarettes speed up bone loss.
  4. Limit alcohol. If you choose to drink alcohol, do so in moderation. For healthy adults, that means up to one drink a day for women of all ages and men older than age 65, and up to two drinks a day for men age 65 and younger.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2659 people found this helpful

3 Ways To Treat Osteoporosis!

MBBS, MS - Orthopaedics
Orthopedist, Coimbatore
3 Ways To Treat Osteoporosis!

Your bone is a living tissue that constantly undergoes the cycle of breakage and replacement. Osteoporosis is a condition wherein the rate at which new bones form cannot match up to the worn out bones, thus making the bones fragile and brittle. Osteoporosis mainly affects the wrist, hip or spine and can result in a stooped posture accompanied by height shrinkage and back pain caused due to a collapsed vertebra.

Reasons Behind Osteoporosis

  1. Hormones: Lowered estrogen count in women and testosterone in men as a result of ageing or other treatments can result in this condition. Excess thyroid secretion in the body, an overactive adrenalin gland or parathyroid gland can also accelerate bone loss. Women are more vulnerable to osteoporosis during menopause.

  2. Prolonged use of injected: Prolonged use of injected or oral corticosteroid medications such as cortisone or prednisone messes with the bone-building process. Medicines used to combat cancer, gastric reflux and seizures can be responsible as well.

  3. Medical Conditions: Certain medical conditions such as rheumatoid arthritis, cancer, liver or kidney disease increases the risks of acquiring osteoporosis.

  4. Sedentary Lifestyle: A sedentary lifestyle with not much physical activity along with an excessive consumption of alcohol and tobacco makes you susceptible to osteoporosis.

Treatments for Osteoporosis:

  1. Medication: Commonly prescribed medicines for remedying fractures include bisphosphonates such as Zoledronic acid, Ibandronate, Risedronate and Alendronate.However these medicines are not free of side-effects such as abdominal pain, nausea or heart burn. In case, your regular medicine doesn’t work, you can use Denosumab and Teriparatide as alternatives but only after consulting your physician.
  2. Hormone Therapy: Estrogen therapy for women after menopause helps sustain bone density. However such procedures can escalate the dangers of getting afflicted with cancer, heart diseases or conditions such as blood clotting.
  3. Alternative Medicine: Ipriflavone, a laboratory manufactured product, when combined with calcium can curb chances of bone loss and alleviate pain. If you wish to discuss about any specific problem, you can consult an orthopedist.
3760 people found this helpful

Parathyroid Hormones and Treatment of Osteoporosis

MBBS, MS - Orthopaedics
Orthopedist, Delhi
Parathyroid Hormones and Treatment of Osteoporosis

A human body has a total of 206 bones, and yet it makes life a living hell, if even one of them is harmed. A person living with Osteoporosis feels the same way, except that they are a lot more prone to having their bones broken than a person who doesn’t. There are a variety of ways to go about treating the issue and one of them involves making use of parathyroid hormones. This is a pathbreaking cure for Osteoporosis and is being adopted by many patients worldwide.

If a person takes a look at the drugs which are made use of in the treatment of osteoporosis, he or she will release that their main function is not to repair what is damaged, but rather to slow the rate of further damage like Bisphosphonate.

However, if parathyroid hormones are looked at, it will be seen that they are usually recommended for those people who may even already had had fractures on account of osteoporosis. These people are generally said to have low bone density, which can be quite dangerous. The reason for this being the case is the fact that when parathyroid hormones are used, they have the potential and the ability to increase the rate of growth of the bones; in terms of the mineral density of the bones as well as the strength of the same.

Teriparatide comes in a pen-like device so that it can be introduced into the body by the way of an injection to either the thigh or the wall of the abdomen. It is important to keep in mind that the medicine should be handled with care which goes to mean that it is to be refrigerated at all times.

It is also to be kept in mind that the medicine can have certain side effects. In most cases in which side effects occur, the medicine leads to some dizziness or some leg cramps.

Taking into due account the fact that the drug is a new one, many doctors would not recommend it to people who have problems with their bones other than those which are caused by osteoporosis. Examples of such conditions would be hypercalcemia, which is a condition in which there is too much calcium in the blood or bone cancer. In addition to this, the medicine is not to be used by a person for a duration which is longer than two years.

All in all, it can be said that if a person makes use of parathyroid hormones to treat a problem that can be as bad as osteoporosis, the effects can be quite startling, and that too, in a positive way! If you wish to discuss about any specific problem, you can consult an orthopedist.

2573 people found this helpful

Curing Long Term Osteoporosis

M.Ch - Orthopaedics - , MS - Orthopaedics, MBBS
Orthopedist, Delhi
Curing Long Term Osteoporosis

Osteoporosis is a condition which usually results due to a decrease in bone density. In this condition, the bones become weak and brittle. Fractures are a common result of osteoporosis. Usually, symptoms or signs do not show up until the condition progresses to its advanced stages.

Since osteoporosis is usually irreversible and incurable, preventing the fractures is considered to be extremely important.

Who is at risk of osteoporosis?
All men and women have some risk of developing 'thinning' of the bones (osteoporosis) as they become older, particularly over the age of 60. As mentioned above, women are more at risk than men. The following situations may also lead to excessive bone loss and so increase your risk of developing osteoporosis. If you:

  1. Are a woman who had the menopause before 45 years of age
  2. Have already had a bone fracture after a minor fall or bump
  3. Have a strong family history of osteoporosis.
  4. Have a body mass index (BMI) of 19 or less (that is, you are very underweight)
  5. Have irregular periods
  6. Have taken, or are taking, a steroid medicine (such as prednisolone) for three months or more
  7. Are a smoker
  8. Have an alcohol intake of more than four units per day
  9. Lack calcium and/or vitamin D (due to a poor diet and/or little exposure to sunlight).
  10. Are mostly inactive

Ways To Treat Osteporosis

Osteoporosis in women can be treated using Hormone Replacement Therapy (HRT). The therapy makes use of either a combination of progestin and oestrogen or simply, oestrogen. However, it is possible that certain combinations have side-effects that might give rise to other medical conditions. Therefore, proper consultation with an orthopedist is an essential pre-requisite so that the condition of osteoporosis as well the side effects may be addressed before proceeding with Hormone Replacement Therapy.

There are a number of medications that can be used which have long-term effects on osteoporosis. However, the schedule for intake of these medicines should be followed diligently. Failing to adhere to the schedule could lead to serious complications. For example, the intake of Risedronate medications (prevent bone loss) should be scheduled once every month, failing which can cause ulcers in the food pipe. Raloxifene has effects which are similar to oestrogen but does not exhibit any serious side effects. Teriparatide can be used to treat osteoporosis in people who have a high risk of suffering from bone fractures.

Don't rely entirely on medication as the only treatment for your osteoporosis. These practices also are important:

  1. Exercise. Weight-bearing physical activity and exercises that improve balance and posture can strengthen bones and reduce the chance of a fracture. The more active and fit you are as you age, the less likely you are to fall and break a bone.
  2. Good nutrition. Eat a healthy diet and make certain that you're getting enough calcium and vitamin D. Being underweight or losing a lot of weight unintentionally is associated with poorer bone health and a higher risk of fracture — even if you're taking a bisphosphonate.
  3. Quit smoking. Smoking cigarettes speed up bone loss.
  4. Limit alcohol. If you choose to drink alcohol, do so in moderation. For healthy adults, that means up to one drink a day for women of all ages and men older than age 65, and up to two drinks a day for men age 65 and younger.
4715 people found this helpful

Osteoporosis - How It Can be Treated?

MCh, DNB (Orthopedics), MS - Orthopaedics, MBBS
Orthopedist, Delhi
Osteoporosis - How It Can be Treated?

Your bone is a living tissue that constantly undergoes the cycle of breakage and replacement. Osteoporosis is a condition wherein the rate at which new bones form cannot match up to the worn out bones, thus making the bones fragile and brittle. Osteoporosis mainly affects the wrist, hip or spine and can result in a stooped posture accompanied by height shrinkage and back pain caused due to a collapsed vertebra.

Reasons Behind Osteoporosis

  1. Hormones: Lowered estrogen count in women and testosterone in men as a result of ageing or other treatments can result in this condition. Excess thyroid secretion in the body, an overactive adrenalin gland or parathyroid gland can also accelerate bone loss. Women are more vulnerable to osteoporosis during menopause.

  2. Prolonged use of injected: Prolonged use of injected or oral corticosteroid medications such as cortisone or prednisone messes with the bone-building process. Medicines used to combat cancer, gastric reflux and seizures can be responsible as well.

  3. Medical Conditions: Certain medical conditions such as rheumatoid arthritis, cancer, liver or kidney disease increases the risks of acquiring osteoporosis.

  4. Sedentary Lifestyle: A sedentary lifestyle with not much physical activity along with an excessive consumption of alcohol and tobacco makes you susceptible to osteoporosis.

Treatments for Osteoporosis:

  1. Medication: Commonly prescribed medicines for remedying fractures include bisphosphonates such as Zoledronic acid, Ibandronate, Risedronate and Alendronate.However these medicines are not free of side-effects such as abdominal pain, nausea or heart burn. In case, your regular medicine doesn’t work, you can use Denosumab and Teriparatide as alternatives but only after consulting your physician.
  2. Hormone Therapy: Estrogen therapy for women after menopause helps sustain bone density. However such procedures can escalate the dangers of getting afflicted with cancer, heart diseases or conditions such as blood clotting.
  3. Alternative Medicine: Ipriflavone, a laboratory manufactured product, when combined with calcium can curb chances of bone loss and alleviate pain. If you wish to discuss about any specific problem, you can consult an orthopedist.
2641 people found this helpful
Table of Content
About Teriparatide
When is Teriparatide prescribed?
What are the side effects of Teriparatide ?
Key highlights of Teriparatide
What are the dosage instructions?
Medicines containing Teriparatide
How does medicine works?