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Overview

Streptase 1500000Iu Injection

Manufacturer: Sanofi India Ltd
Medicine composition: Streptokinase
Prescription vs.OTC: Prescription by Doctor required

Streptase 1500000Iu Injection is used for the treatment of blood clots in the blood vessels, helping them to dissolve and enhance the smooth circulation of blood in the body. It is an emergency treatment that is administered to save the life of a patient who has just had a cardiac arrest. The medicine is known to be helpful in case of deep vein thrombosis in the legs, or pulmonic embolism, that is the formation of blood clots inside the lungs. Streptase 1500000Iu Injection may also treat any thickening or solidifying of blood inside the catheter that is inserted into blood vessels. The medicine is available only on prescription. You must take your doctor’s advice if you are pregnant, planning a pregnancy any time soon or a breastfeeding mother. You must make the doctor of any allergies that you may have to drugs, food or any other substances. It is important to also let your doctor know if you are on any other kind of prescription drugs, or dietary supplements that you may be taking, as a number of drugs may interact with Streptase 1500000Iu Injection and create unwanted complications. Streptase 1500000Iu Injection must be administered with caution in patients suffering from high blood pressure, kidney, liver or lung complications.

In addition to its intended effect, Streptase 1500000Iu Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Decrease in blood pressure
Injection site bleeding.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Stpase 1500000iu injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
There is no data available. Please consult doctor before consuming the drug.
Does this affect kidney function?
There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Streptase 1500000Iu Injection, and hence can be used as its substitute.
Bharat Serums & Vaccines Ltd
Cadila Pharmaceuticals Ltd
Life Medicare & Biotech Pvt Ltd
Alembic Pharmaceuticals Ltd
Aristo Pharmaceuticals Pvt Ltd
Vhb Life Sciences Inc
Biosena Lifescience
Dabur India Ltd
Are there any missed dose instructions?
If you miss a dose of Streptokinase, please consult your doctor.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

What is thombroysis? N can a heart get another attack after 3 attacks n successful double bypass surgery ie valve replacement n artery bypass?

Diploma in Obstetrics & Gynaecology, MBBS
General Physician, Delhi
What is thombroysis? N can a heart get another attack after 3 attacks n successful double bypass surgery ie valve rep...
Thrombroysis is breaking a clot, immediately after a heart attack if thrombolytic medicines like streptokinase are given, it does help the afflicted person. 1st heart attack is like a shock when person asks himself -why me? it happens to others only! 2nd attack occurs if person is careless about food, high cholesterol and high bp & high sugar & higher weight are not under control, person keeps on smoking / gets exposed to pollution and low levels of oxygen in atmosphere does trigger a heart attack, no exercise or taking negative stress to the heart, everything that causes a heart attack has been ignored despite suffering from one, bypass surgery + valve replacement should work like a shock and one needs to reassure self that no more'encounters" with cardiac ot or exposure to everything that is not friends of heart except the doctors who do suggest annual check ups.
2 people found this helpful

I had a test for TSH (for thyroid) and result gives immunology count as 5.3uIU/ml. Is this a problem & if it is then what are the effects of it.

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
I had a test for TSH (for thyroid) and result gives immunology count as 5.3uIU/ml. Is this a problem & if it is then ...
Hi, Normal TSH levels for the average adult range from 0.4 ‑ 4.0 mIU/L (milli-international units per liter). You have hypothyroidism and need medication.
1 person found this helpful

I have done hbsag test on, 28 dec, report I got 0.31 non reactive what is it and what is report saying.

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
I have done hbsag test on, 28 dec, report I got 0.31 non reactive what is it and what is report saying.
You do not have infection with HbsAg, the report says. Any value between 1 and 5 s/c is indeterminate and should be repeated. For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. Any value between 5 and 12 mIU is indeterminate and should be repeated.
1 person found this helpful

I am 21 years old I have hepatitis B virus results less than 20 IU/ML. What should I do? I haven't done any treatment on it so advice me some treatment on this.

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
I am 21 years old I have hepatitis B virus results less than 20 IU/ML. What should I do? I haven't done any treatment...
For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. Any value between 5 and 12 mIU is indeterminate and should be repeated

How to improve female fertility I am suffering from Low ovum (egg) how to improve. Please suggest my AMH level 1.23.

MD - Obstetrtics & Gynaecology, DGO
IVF Specialist, Mumbai
How to improve female fertility I am suffering from Low ovum (egg) how to improve. Please suggest my AMH level 1.23.
Please note there are supplements available which can help in improving the AMH. These supplements are antioxidants.
2 people found this helpful

Popular Health Tips

Taking Medicines during Pregnancy: Safe and Unsafe Medications

MBBS, DGO, MD - Obstetrics & Gynaecology, MRCOG
Gynaecologist, Delhi
Taking Medicines during Pregnancy: Safe and Unsafe Medications

Normal pregnancy lasts for 38 to 42 weeks. However, there may be times during these weeks that you may have some physical issues such as vomiting, backache, and loose stools etc which require treatment with medicines.

Therefore, monitoring and managing these physical conditions becomes necessary to ensure a normal delivery. Management consists of both medicines and rehabilitation. Medicines are considered to be the first line of treatment; however, the health care provider needs to take care while prescribing medicines during pregnancy taking into consideration the harmful effects they can have on both – the mother and the foetus.  Medicines pass on via the placenta from the mother to the foetus. Hence, before prescribing any medicine the provider should check the possibilities of the medicine causing any congenital defect. You should avoid medicines from the time of conception till the first 10 weeks, as this is the time when the foetus is most prone to the get permanent congenital deformities. Medicines given in the later stages (after 10 weeks) may cause systemic damage. For example NSAIDs (Non Steroidal Anti-Inflammatory Drugs) may lead to problems during labour or organ defects in the foetus.

Therefore, medicines should always be avoided during pregnancy. Still there are certain medicines, which can be taken but after consulting your physician. Let’s discuss the medicines that are safe during pregnancy.

The following is a list of medicines and their effects during pregnancy:

1. Analgesic Medicines

Paracetamol Safe
NSAIDs, such as aspirin May cause heart abnormalities in the third trimester

2. Opiates 

Codeine Effective in low doses
Hydrocodone Effective in low doses
Hydromorphone Effective in low doses

3. Anaesthetics 

Etomidate Unknown always ask your provider
Ketamine Avoid during the last trimester
Lorazepam Avoid for severe conditions, safe for short periods

4. Thrombolytics - The possible advantages of this class may balance the risk during pregnancy. Common medicines used are: Alteplase, Reteplase, Streptokinase, Urokinase.

5. Antidotes

Hydroxycobalamin antidote: cyanide Safe
Methylene blue antidote: methemoglobinemia Has a potential risk to the mother and foetus

6. Penicillins

First generation: penicillin G, benzathine penicillin, Bicillin, penicillin VK Safe
Second generation: oxacillin, dicloxacillin, nafcillin Safe

7. Cardiac agents

Adenosine Safe
Digoxin Not advised in third trimester
Lidocaine Safe

8. Diabetes: Insulin is safe to use during diabetes.

9. Antacids

Famotidine Low risk
Ranitidine Safe

10. Corticosteroids: Advised for short term use

Cetirizine Almost safe
Chlorpheniramine Safe

Always talk to your physician in case of any complication and before taking any medicine given above.

4 people found this helpful

Safe and Unsafe Medications to Take While Pregnant

MBBS, DGO, MD - Obstetrics & Gynaecology, MRCOG
Gynaecologist, Delhi
Safe and Unsafe Medications to Take While Pregnant

Which medicines are safe to use during Pregnancy?

Normal pregnancy lasts for 38 to 42 weeks. However, there may be times during these weeks that you may have some physical issues such as vomiting, backache, and loose stools etc which require treatment with medicines.

Therefore, monitoring and managing these physical conditions becomes necessary to ensure a normal delivery.Management consists of both medicines and rehabilitation.Medicines are considered to be the first line of treatment; however, the health care provider needs to take care while prescribing medicines during pregnancy taking into consideration the harmful effects they can have on both – the mother and the foetus.  Medicines pass on via the placenta from the mother to the foetus. Hence, before prescribing any medicine the provider should check the possibilities of the medicine causing any congenital defect. You should avoid medicines from the time of conception till the first 10 weeks, as this is the time when the foetus is most prone to the get permanent congenital deformities. Medicines given in the later stages (after 10 weeks) may cause systemic damage. For example NSAIDs (Non Steroidal Anti-Inflammatory Drugs) may lead to problems during labour or organ defects in the foetus.

Therefore, medicines should always be avoided during pregnancy. Still there are certain medicines, which can be taken but after consulting your physician. Let’s discuss the medicines that are safe during pregnancy.

The following is a list of medicines and their effects during pregnancy:

1. Analgesic Medicines

Paracetamol Safe
NSAIDs, such as aspirin May cause heart abnormalities in the third trimester

2. Opiates

Codeine Effective in low doses
Hydrocodone Effective in low doses
Hydromorphone Effective in low doses

3. Anaesthetics

Etomidate Unknown always ask your provider
Ketamine Avoid during the last trimester
Lorazepam Avoid for severe conditions, safe for short periods

4. Thrombolytics - The possible advantages of this class may balance the risk during pregnancy. Common medicines used are: Alteplase, Reteplase, Streptokinase, Urokinase.

5. Antidotes

Hydroxycobalamin antidote: cyanide Safe
Methylene blue antidote: methemoglobinemia Has a potential risk to the mother and foetus

6. Penicillins

First generation: penicillin G, benzathine penicillin, Bicillin, penicillin VK Safe
Second generation: oxacillin, dicloxacillin, nafcillin Safe

7. Cardiac agents

Adenosine Safe
Digoxin Not advised in third trimester
Lidocaine Safe

8. Diabetes: Insulin is safe to use during diabetes.

9. Antacids

Famotidine Low risk
Ranitidine Safe

10. Corticosteroids: Advised for short term use

Cetirizine Almost safe
Chlorpheniramine Safe

Always talk to your physician in case of any complication and before taking any medicine given above.

Pregnancy and Fertility in Thyroid Disorders!

MBBS, DNB (Obstetrics and Gynecology), FNB
Gynaecologist, Delhi
Pregnancy and Fertility in Thyroid Disorders!

The human body works as directed by the various hormones released by the endocrine system. These hormones are essential for coordination of various body functions. From the height a person achieves to the metabolic reactions in the body to the reproductive cycle to the stress levels a person can handle, all are hormone controlled.

Pregnancy is another critical, complicated phase that a woman goes through. It is one of the most awaited phases in a woman’s life; however, it is not very simple either. The above-noted hormones play a major role in this pregnancy, as the baby is dependent on the mother for its initial supply of hormones until it can start producing its own hormones. If the baby does not receive the require amounts, there could be various detrimental effects during development and post birth.

Hypothyroidism or an underactive thyroid is extremely common in women and there are multiple theories about how hypothyroidism can affect a woman’s chances of getting pregnant. While the correlation between hypothyroidism and pregnancy are quite well researched, a strong connection stating hypothyroid women being not able to be pregnant is yet to be proven.

The following are some correlations between hypothyroidism and pregnancy.

Increased chance of miscarriage: Women with reduced thyroid functions have double the chances of having a miscarriage. Women suffering from thyroid are at a risk of recurrent miscarriages during the first trimester. The chances of miscarriages during the second trimester are also about 40% higher in hypothyroid women. These women are also at a risk of:

  1. Premature labour
  2. Low birth weight
  3. Increased chances of stillbirth
  4. Maternal anemia
  5. Postpartum hemorrhage
  6. Developmental defects and/or delays in the newborn
  7. Placental abruption
  8. High blood pressure

One of the reasons identified for infertility in women is hypothyroidism. This range varies from 1% to 40% and so remains to be proven still. In addition, the hypothyroid mother will have a set of symptoms to live through, which may be further complicated given the pregnancy. Thyroid replacement should be religiously done and monitored to ensure TSH levels are at the optimal required levels (2.5 to 3 mIU/L) during the entire duration of pregnancy.

If you have the following, be sure to go through a comprehensive thyroid screening before and during pregnancy.

  1. Family history of thyroid
  2. History of thyroid dysfunction or goitre or thyroid antibodies
  3. Clinical signs and symptoms suggestive of hypothyroidism
  4. History of repeated miscarriages
  5. History of head and neck radiation
  6. Family/personal history of autoimmune disorders

While it still remains to be proven that hypothyroidism per se can stop a woman from being pregnant, there are definitely effects of hypothyroidism on the developing child and the mother. A comprehensive screening and close monitoring through pregnancy are extremely essential. If you wish to discuss about any specific problem, you can consult a Gynaecologist.

3975 people found this helpful

Dislocated Kneecap - Symptoms and Treatment

MS - Orthopaedics
Orthopedist, Chennai
Dislocated Kneecap - Symptoms and Treatment

Have you suffered from a dislocated kneecap and are looking for effective treatment options? A dislocated kneecap is a very common form of injury that takes around six weeks time to heal. It is generally caused by a blow or a change in direction when your leg is planted on the ground. Such injuries are common during sports and dancing. The patella or knee cap, which sits at the front of the knee, glides over a groove in your joint, on straightening or bending your leg. Dislocations make it come out of the groove, leading to the tearing of the supporting tissues.

Symptoms

  • When your kneecap gets dislocated, it is likely to look out of place, or the angle will seem odd.
  • Other symptoms include severe knee pain, inability to walk, swelling of the knee, inability to straighten the knee, and a popping sensation in the knee.

Treatment

  • A dislocated knee cap is not something very serious and it pops back in place on its own in many cases. However, it is recommended for you to get it diagnosed and treated by a health professional.
  • In case your knee cap goes back into place on its own, you should visit a minor injuries unit or MIU, or an accident and emergency department.
  • If your kneecap does not go back into place by itself, you need to call an ambulance and avoid trying to put it back in place by yourself.
  • On the way to the hospital, or while you wait for the ambulance to arrive, you should sit, keeping your leg in a position that is most comfortable for you.
  • If your kneecap does not correct itself by the time you reach a hospital, it has to be manipulated back in place by a doctor. This process is called reduction.
  • You will be given medication to ensure that you keep relaxed and free from pain during the procedure.
  • After the knee cap is put back in place, an X-ray has to be undertaken to check out if your bones are in the right position. Signs of other damages are also analysed.
  • After the procedure, you will be prescribed painkillers. Your leg will be immobile and put in a removable splint for some time.
  • For effective recovery, you should undergo physiotherapy for several weeks.

A surgery for a dislocated kneecap may only be required to be undertaken in case of a fracture or associated injuries like a ligament tear. A surgery may also be required in case you had experienced a knee cap dislocation in the past. If you wish to discuss about any specific problem, you can consult an orthopedist.

2832 people found this helpful

Thyroid - Can it Prevent You from Getting Pregnant?

MBBS, MS - Obstetrics and Gynaecology
Gynaecologist, Agra
Thyroid - Can it Prevent You from Getting Pregnant?

The human body works as directed by the various hormones released by the endocrine system. These hormones are essential for coordination of various body functions. From the height a person achieves to the metabolic reactions in the body to the reproductive cycle to the stress levels a person can handle, all are hormone controlled.

Pregnancy is another critical, complicated phase that a woman goes through. It is one of the most awaited phases in a woman’s life; however, it is not very simple either. The above-noted hormones play a major role in this pregnancy, as the baby is dependent on the mother for its initial supply of hormones until it can start producing its own hormones. If the baby does not receive the require amounts, there could be various detrimental effects during development and post birth.

Hypothyroidism or an underactive thyroid is extremely common in women and there are multiple theories about how hypothyroidism can affect a woman’s chances of getting pregnant. While the correlation between hypothyroidism and pregnancy are quite well researched, a strong connection stating hypothyroid women being not able to be pregnant is yet to be proven.

The following are some correlations between hypothyroidism and pregnancy.

Increased chance of miscarriage: Women with reduced thyroid functions have double the chances of having a miscarriage. Women suffering from thyroid are at a risk of recurrent miscarriages during the first trimester. The chances of miscarriages during the second trimester are also about 40% higher in hypothyroid women. These women are also at a risk of:

  1. Premature labour
  2. Low birth weight
  3. Increased chances of stillbirth
  4. Maternal anemia
  5. Postpartum hemorrhage
  6. Developmental defects and/or delays in the newborn
  7. Placental abruption
  8. High blood pressure

One of the reasons identified for infertility in women is hypothyroidism. This range varies from 1% to 40% and so remains to be proven still. In addition, the hypothyroid mother will have a set of symptoms to live through, which may be further complicated given the pregnancy. Thyroid replacement should be religiously done and monitored to ensure TSH levels are at the optimal required levels (2.5 to 3 mIU/L) during the entire duration of pregnancy.

If you have the following, be sure to go through a comprehensive thyroid screening before and during pregnancy.

  1. Family history of thyroid
  2. History of thyroid dysfunction or goitre or thyroid antibodies
  3. Clinical signs and symptoms suggestive of hypothyroidism
  4. History of repeated miscarriages
  5. History of head and neck radiation
  6. Family/personal history of autoimmune disorders

While it still remains to be proven that hypothyroidism per se can stop a woman from being pregnant, there are definitely effects of hypothyroidism on the developing child and the mother. A comprehensive screening and close monitoring through pregnancy are extremely essential. If you wish to discuss about any specific problem, you can consult a gynaecologist.

3914 people found this helpful

Table of Content

About Streptase 1500000Iu Injection
When is Streptase 1500000Iu Injection prescribed?
What are the side effects of Streptase 1500000Iu Injection?
Key highlights of Streptase 1500000Iu Injection
What are the substitutes for Streptase 1500000Iu Injection?
What are the dosage instructions?
What are the interactions for Streptase 1500000Iu Injection?