Pyrigesic 500 MG Tablet

Pyrigesic 500 MG Tablet is used a pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis and toothache, etc.

The active ingredient falls under the class of analgesics, belonging to the category of NSAID. This medication also reduces pain in the body caused due to fever.

You should not consume this tablet if:

• You are allergic to this medicine.
• You are suffering from a serious liver disorder.
• You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

There are several drugs that may interact with Pyrigesic 500 MG Tablet. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over the counter drugs and herbal products.

For adults Pyrigesic 500 MG Tablet the general dose for fever and pain is 325-650 mg tablets once in every 4 to 6 hours or 1000mg tablets once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

For adults Paracetamol the general dose for fever and pain is 325-650 mg once in every 4 to 6 hours or 1000 mg once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

For treating Pyrigesic 500 MG Tablet toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.

Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.

• Fever

• Headache

• Muscle Pain

• Menstrual Cramps

• Post Immunization Pyrexia

• Arthritis

• Allergy

• Analgesic Nephropathy (Kidney Disease)

• Liver Disease

• Nausea Or Vomiting

• Allergic Skin Reaction

• Gastric / Mouth Ulcer

• Anemia

• Fatigue

• Stevens-Johnson Syndrome (Sjs)

• How long is the duration of effect?

  The effect lasts for an average of 4-6 hours.

• What is the onset of action?

  The effect of Paracetamol (primary constituent of Pyrigesic 500 MG Tablet) can be observed within an hour of oral administration. When given in the form of an intravenous injection, the pain-relieving action starts in 5-10 minutes. For fever reduction, the time taken is about 30 minutes.

• Are there any pregnancy warnings?

  This medicine is not known to cause any harm to the fetus. But the evidence is inadequate and it should be used only when necessary after consulting a doctor. Oral administration of the medicine should be preferred over intravenous route.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine.

• Does this affect liver function?

  Appears to be well tolerated in cirrhosis; serum levels may need monitoring with long-term use.

• Does this affect kidney function?

  Dose adjustment is needed in case of renal impairment. Consult your doctor before taking this medication.

• Is It safe with alcohol?

  Excessive intake of alcohol may increase the risk of acetaminophen-induced hepatotoxicity; avoid or limit alcohol intake.

Below is the list of medicines, which have the same composition, strength and form as Pyrigesic 500 MG Tablet , and hence can be used as its substitute.

• Amol 500 MG Tablet

  Unichem Laboratories Ltd

• Doliprane 500 MG Tablet

  Abbott Healthcare Pvt. Ltd

• Dolocare 500 MG Tablet

  Alkem Laboratories Ltd

• T98 500 MG Tablet

  Mankind Pharmaceuticals Ltd

• Cule 500 MG Tablet

  Medley Pharmaceuticals

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

This medication is a pain relief medication that is administered both orally and intravenously. It selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  You should avoid consuming alcohol while taking this medicine. Symptoms like fever, chills, rashes, joint pain and swelling, excessive weakness, nausea should be immediately reported to the doctor.

• Interaction with Lab Test

  5-HIAA Urine Test

  You may get a false-positive result for this test if you take Pyrigesic 500 MG Tablet.

• Interaction with Medicine

  One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives if administered concomitantly. Also, Barbiturates, carbamazepine, hydantoins, sulfinpyrazone can increase the hepatotoxic potential of acetaminophen; chronic ethanol abuse increases the risk for acetaminophen toxicity; effect of warfarin may be enhanced.

• Interaction with Disease

  Patients suffering from liver disease should use some other safer alternative.

• Interaction with Food

  May slightly delay absorption of extended-release preparations; rate of absorption may be decreased when given with food high in carbohydrates

• Ques : What is Pyrigesic 500 MG Tablet?

  Ans : Pyrigesic is used to temporarily relieve fever and mild to moderate pain such as muscle ache, headache, toothache, arthritis, and backache. It contains Paracetamol as an active ingredient. This medication works by blocking the release of certain chemical messengers that cause pain and fever.

• Ques : What are the uses of Pyrigesic 500 MG Tablet?

  Ans : Pyrigesic is used for the treatment and prevention from conditions and symptoms of diseases like fever, headache, and muscle pain.

• Ques : What are the Side Effects of Pyrigesic 500 MG Tablet?

  Ans : Side effects include nausea or vomiting, fever, allergic skin reaction, and mouth ulcer. Apart from these, using this medicine may further lead to anemia, fatigue, gastric ulcer, and unusual bleeding or bruising. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

• Ques : What are the instructions for storage and disposal Pyrigesic 500 MG Tablet?

  Ans : Pyrigesic tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : How long do I need to use Pyrigesic 500 MG Tablet before I see improvement of my conditions?

  Ans : This medication takes 1 or 2 days before you see an improvement in your health conditions.

• Ques : What are the contraindications to Pyrigesic 500 MG Tablet?

  Ans : This tablet should not be used if you have the following conditions such as skin rashes, skin reddening, and skin blisters.

• Ques : Is Pyrigesic 500 MG Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

• Ques : Will Pyrigesic 500 MG Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of this tablet can lead to increased chances of side effects such as bleeding, breathing problems, itching, mouth ulcers, skin rash, swelling of the face, swelling of the lips, swelling of the throat, and swelling of the tongue.

• Ques : Should I use Pyrigesic 500 MG Tablet empty stomach, before food or after food?

  Ans : If you take this medication with the food, the reactions that took place in the body carry-outs in a much effective manner.

• Ques : Is there any food or drink I need to avoid while taking Pyrigesic 500 MG Tablet?

  Ans : You can follow your normal diet under the usage of this medication.

• Ques : Will Pyrigesic 500 MG Tablet be more effective if taken in more than the recommended dose?

  Ans : There is no need to take this medication more than its recommended doses.

• Ques : Can I take other medications along with Pyrigesic 500 MG Tablet?

  Ans : Do not use any OTC for cough, cold, allergy, or pain medication without consulting your doctor or pharmacist. Pyrigesic 500 MG Tablet contains many combination of medicines. If you use certain products together you may accidentally use too much of Pyrigesic 500 MG Tablet.

• Ques : Can I take Pyrigesic 500 MG Tablet with antibiotics?

  Ans : There are hundreds of antibiotics used to treat infections, so once you receive your prescription, ask your doctor or pharmacist if you can also take this medication at the same time that you take the antibiotic.

• Ques : Is Pyrigesic 500 MG Tablet an NSAID drug?

  Ans : No, this medication is not classified as an NSAID (nonsteroidal anti-inflammatory drug). It is classified as a miscellaneous analgesic for mild to moderate pain and fever.

• Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

• Anadin Paracetamol Tablets- EMC [Internet]. www.medicines.org.uk. 2016 [Cited 24 April 2019]. Available from:

  https://www.medicines.org.uk/emc/product/3875/smpc

• Acetaminophen- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 27 April 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00316