Od Capsule

OD Capsule is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Omeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Od Capsule is a combination of Domperidone and Omeprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

OD Capsule also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Od Capsule if you have the following conditions:

• An allergy to Od Capsule or any other ingredient of this medicine
• Bleeding problems or blockage in your stomach or in the intestine
• Tumour in the pituitary gland
• Cardiac disease
• Incorrect levels of magnesium, potassium or calcium in the blood
• Severe /moderate liver impairment

• Gastroesophageal Reflux Disease

• Peptic Ulcer

• Allergy

• Tumor Of Pituitary Gland

• Heart Diseases

• Skin Rash

• Diarrhoea

• Headache

• Stomach Pain

• Dizziness

• Weakness

• Dry Mouth

• Cough

• Rhinitis

• Flatulence

• Insomnia

• How long is the duration of effect?

  The effect of this medication lasts up to 6 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed within 30 to 60 minutes of administration.

• Are there any pregnancy warnings?

  This medicine should be avoided by pregnant women unless suggested by the doctor.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use by breastfeeding mothers as there is a risk of side effects on the infant.

Below is the list of medicines, which have the same composition, strength and form as Od Capsule , and hence can be used as its substitute.

• Lokcidom 10 mg/20 mg Tablet

  Tas Med India Pvt Ltd

• Minisec Ar 10 Mg/20 Mg Tablet

  Pulse Pharmaceuticals

• Omlink D Capsule

  Lincoln Pharmaceuticals Ltd

• Aciloc RD Tablet

  Cadila Pharmaceuticals Ltd

• Omesec-Rd Capsule

  Sun Pharmaceutical Industries Ltd

• Domzole 10 mg/20 mg Tablet

  Alkem Laboratories Ltd

• Ordom 10 Mg/20 Mg Capsule

  BestoChem Formulations India Ltd

• Valv D Capsule

  Spenchem Pharmaceuticals Pvt Ltd

• Gr8 10Mg/20Mg Capsule

  Franco-Indian Pharmaceuticals Pvt Ltd

• Om-Dd Capsule

  Pinenut Life Care India Pvt Ltd

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected.

This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Lab Test

  The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.

• Interaction with Medicine

  Medicine

  Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

• Interaction with Disease

  • Kidney Disease: This medication should be used with caution if you are suffering from impaired kidney function. Suitable dose adjustment and safety monitoring is advised, especially if the impairment is severe.
  • Liver Disease: This medicine should be used with caution if you are suffering from impaired liver function. Suitable dose adjustment and safety monitoring are advised, especially if the impairment is mild to moderate. For severe impairment, the use of this medicine is not recommended.
  • Intestinal Disorders: This medication should be used with extreme caution in people having serious intestinal problems like internal bleeding, an obstruction or perforation of the stomach and intestine. Use of alternate medicine is advised in such cases.

• Ques : What is Od Capsule?

  Ans : The capsule is a medication which has Domperidone and Omeprazole as active ingredients present in it. This medicine performs its action by obstructing the release of dopamine receptors.

• Ques : What are the uses of Od Capsule?

  Ans : This capsule is used for the treatment and prevention from conditions and symptoms of diseases like intestinal ulcer, gastroesophageal reflux diseases, intractable nausea, and Vomiting.

• Ques : What are the Side Effects of Od Capsule?

  Ans : The side effects include pruritus, breast tenderness, Akathisia, and skin rashes.

• Ques : What are the instructions for storage and disposal Od Capsule?

  Ans : The capsule should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 27 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/domperidone

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 27 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184

• Omeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 27 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/omeprazole

• Omeprazole- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 27 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00338