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Glibenclamide 2.5 MG Tablet

Manufacturer: Cipla Ltd
Medicine composition: Glibenclamide
Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 14, 2018

Glibenclamide 2.5 MG Tablet is used in the treatment of diabetes mellitus. Insulin, a hormone produced by the body metabolizes sugar in the blood. When the body does not produce insulin in the required amounts, the blood sugar level in the body increases. This results in diabetes.

A diabetic patient has to maintain his blood sugar levels by following a healthy lifestyle like avoiding sugar in food. Glibenclamide 2.5 MG Tablet activates the pancreas to secrete more insulin. This medication is taken alongside a healthy diet. More insulin helps to reduce the level of sugar in the blood.

Consult with your doctor if you have the following conditions – you are pregnant or breast feeding; allergic reactions to a medicine; problems in the kidney or liver. Let your doctor if you are taking other medications before starting a course of Glibenclamide 2.5 MG Tablet.

Follow the prescribed dosage carefully which is around 5 mg on a daily basis. It is recommended to skip a dose if you have missed one, do not take multiple doses at once. You may experience certain side effects like nausea, constipation, low blood sugar, weight gain and diarrhea after taking this medication. Consult a doctor immediately if you experience these side effects. The side effects generally tend to improve as the body gets used to the medication.

It is advised to store the medication in a dry and cool place. Make sure the medicine is not exposed to direct light.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Diabetologist before using this medicine.

  • Type 2 Diabetes Mellitus

    Glibenclamide 2.5 MG Tablet is used for the reduction of blood sugar levels in patients suffering from Type II diabetes mellitus. It is recommended to follow a controlled diet and exercise regularly along with taking this medicine to obtain better results.
  • Allergy

    This medicine is not recommended for use if you have a known history of allergy to it or any other medicine belonging to the same class which is Sulfonylureas.
  • Diabetic Ketoacidosis

    This medicine is not recommended for use if you have a condition where ketone bodies are present in the urine. It applies to ketoacidosis with or without coma.
  • Type I Diabetes Mellitus

    This medicine is not recommended for use if you suffer from insulin dependent diabetes or gestational diabetes.
  • Bosentan

    This medicine is not recommended for use in patients who are taking Bosentan. The risk of side effects are extremely high when these medicines are used together.
  • Nausea

  • Heartburn

  • Abdominal Fullness

  • Yellow Colored Eyes Or Skin

  • Dark Colored Urine

  • Fever Or Chills

  • Swelling Of Face, Lips, Eyelids, Tongue, Hands And Feet

  • Unusual Bleeding

  • Fast Heartbeat

  • Unusual Tiredness And Weakness

  • How long is the duration of effect?

    The effect of this medicine lasts for an average duration of 24 hours.
  • What is the onset of action?

    The effect of this medicine can be observed within 15-60 minutes of administration.
  • Are there any pregnancy warnings?

    Use of this medicine in pregnant women is not recommended unless absolutely necessary. It should be used only when the benefits clearly outweigh the risks involved. It is advised to consult your doctor before taking this medicine.
  • Is it habit forming?

    No habit forming tendencies were reported.
  • Are there any breast-feeding warnings?

    Use of this medicine is not recommended while breastfeeding. Monitoring of the infant for signs of decreased blood sugar may be required if this medicine is taken. You should consult your doctor before taking this medicine.

Below is the list of medicines, which have the same composition, strength and form as Glibenclamide 2.5 MG Tablet , and hence can be used as its substitute.

  • Missed Dose instructions

    Take the missed dose as soon as you remember with food. However, if it is almost time for the next scheduled dose then the missed dose can be skipped.
  • Overdose instructions

    Contact a doctor immediately if an overdose is suspected. Symptoms of overdose may include confusion, sweating, weakness, vomiting, fainting, seizures etc.
  • India

  • United States

  • Japan

Glibenclamide 2.5 MG Tablet lowers blood sugar levels by stimulating the production of insulin from the pancreatic beta cells.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Disease

    Heart Diseases

    This medicine should be administered with extreme caution if you suffer from a disease of heart or blood vessels. Risks of severe to fatal adverse effects are very high in such patients.

    Diabetic Ketoacidosis

    This medicine should not be used in patients having high acid content in blood as the risk of adverse effects are very high.

    Kidney Disease

    This medicine should be administered with extreme caution if you suffer from any disease of the kidneys. You should consult your doctor to make a suitable adjustment in dosage quantity and/or time-interval between two dosages.

    Liver Disease

    This medicine should be administered with extreme caution if you suffer from any disease of the liver. You should consult your doctor to make a suitable adjustment in dosage quantity and/or time-interval between two dosages.

    Hypoglycemia

    This medicine should be administered with caution if you are prone to having episodes of low blood sugar. This population includes diabetics who are also malnourished or those receiving Beta-blocker drugs such as Metoprolol and Propranolol.

    Hemolytic Anemia/G6Pd Deficiency

    This medicine is not recommended for use in people suffering from Hemolytic Anemia. Reporting this condition to the doctor is a must. In such cases, alternate medication not belonging to Sulfonylureas should be considered.
  • Interaction with Alcohol

    Ethanol

    Consumption of alcohol in large quantities is not recommended when you are taking this medicine for controlling blood sugar levels. It is recommended to reduce the alcohol intake so that the adverse effects can be avoided. Symptoms of both reduced or elevated blood sugar levels should be reported to the doctor immediately.
  • Interaction with Lab Test

    Lab

    Information not available.
  • Interaction with Food

    Food

    Information not available.
  • Interaction with Medicine

    Atenolol

    Report the use of any blood pressure medication to the doctor before receiving Glibenclamide. You may need a more frequent monitoring of blood glucose levels while taking these medicines together.

    Clarithromycin

    Report the use of any antibiotic medication to the doctor. You may need an adjusted dose of Glibenclamide and more frequent monitoring of blood sugar levels while taking them together.

    Gatifloxacin

    Report the use of either of the medication to the doctor. These medicines should not be used together. Moderate to severe levels of fall in blood sugar have been frequently reported. Sometimes it may also cause an increase in blood sugar levels. Your doctor may prescribe alternatives that do not interact with each other.

    Ethinyl Estradiol

    Report the use of any birth control pill containing Ethinyl estradiol or other related compounds to the doctor. You may need an adjusted dose of Glibenclamide while taking them together.

    Bosentan

    Report the use of either of the medicine to the doctor. These medicines should not be used together as the risk of severe adverse effects are fairly high on co-administration.

    Ibuprofen

    Report the use of Ibuprofen or any other pain medication to the doctor. These medications can cause a fall in blood sugar levels. You may need a dose adjustment and more frequent monitoring of blood sugar levels while taking them together.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Glibenclamide 2.5 MG Tablet
What are the uses of Glibenclamide 2.5 MG Tablet
What are the contraindications of Glibenclamide 2.5 MG Tablet ?
What are the side effects of Glibenclamide 2.5 MG Tablet ?
Key highlights of Glibenclamide 2.5 MG Tablet
What are the substitutes for Glibenclamide 2.5 MG Tablet ?
What are the dosage instructions?
Where is the Glibenclamide 2.5 MG Tablet approved?
How does this medication work?
What are the interactions of Glibenclamide 2.5 MG Tablet ?