Manufacturer: Corona Remedies Pvt Ltd
Medicine composition: Methylcobalamin, Nortriptyline, Pregabalin
Prescription vs.OTC: Prescription by Doctor not required

GB 29 Total is used to treat neuropathic pain & helps the body to produce red blood cells. Being a combination medication containing Methylcobalamin, Nortriptyline, Pregabalin, it is used as a dietary supplement.

GB 29 TOTAL TABLET is a combination of medicine that works through multiple mechanisms. The main active constituents of this medicine are nortriptyline and pregabalin.

Nortriptyline falls under a category of medications called tricyclic antidepressants. Pregabalin is an anticonvulsant & is considered to be the first-line of treatment for neurotic pain, shingles, seizures, and fibromyalgia.

GB 29 Total also helps in treating diabetic nerve pain, epilepsy, spinal cord injury, restless leg syndrome, and generalized anxiety disorder. GB 29 TOTAL TABLET also helps in curing certain mental/ mood disorders.

GB 29 Total works by binding a certain region of the brain and reduces the pain signals sent out by the damaged nerves of the body. It also prevents megaloblastic or pernicious anemia that leads to weakness, fatigue, numbness of fingers, toes and problems in thinking.

Also Read: Myospaz Tablet Combination

GB 29 Total is helpful in treating the below provided problems:

  • Neuropathic Pain

Common side effects of GB 29 Total Tablet are as follows:

  • How long is the duration of effect?

    GB 29 Total is eliminated from the body via faeces. However, the duration of action is not clearly established.
  • What is the onset of action?

    The peak effect of this medication is achieved withing 3 hours of oral administration. However, upon topical and vaginal application, the absorption is very slow.
  • Are there any pregnancy warnings?

    Till the first trimester of pregnancy, the oral and topical forms of this medicine are safe for consumption. It, however, should only be used when extremely needed. The medicine should not be consumed in oral form during pregnancy. Doctor consultation to evaluate potential benefits and risks before consumption is mandatory.
  • Is it habit forming?

    No habit forming tendencies were reported.
  • Are there any breast-feeding warnings?

    The excretion of this medication in breast milk is not known. Consult your doctor if you are breastfeeding while using this medication.
  • Is It safe with alcohol?

    Alcohol should not be consumed while on this medication.
  • Is it safe to drive while on this medicine?

    It is not safe to drive while you are on this medication since it causes drowsiness and dizziness.
  • Does this affect kidney function?

    Patients with kidney disease should be cautious while taking this medicine. Consult your doctor for alternatives or dosage adjustments.
  • Does this affect liver function?

    It is safe for patients with liver disease.

Below is the list of medicines, which have the same composition, strength and form as GB 29 TOTAL TABLET , and hence can be used as its substitute.

  • Are there any missed dose instructions?

    Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose.
  • Are there any overdose instructions?

    Contact your doctor if an overdose is suspected.

This medication acts as a cofactor for enzyme methionine synthase, which transfers methyl groups for the regeneration of methionine from homocysteine. In anemia, it increases blood cell production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes. Also, it binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Lastly, it blocks the norepinephrine presynaptic receptors which in turn inhibits norepinephrine reuptake. This raises its concentration in the synaptic clefts of the CNS. It also blocks reuptake of serotonin at the neuronal membrane.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Alcohol consumption is not recommended while taking this tablet since it increases drowsiness and calmness.
  • Interaction with Medicine

    Certain drugs should be avoided while on this medication like Antidiabetic drugs, benzodiazepines, sedatives and angiotensin-converting-enzyme inhibitors since they cause difficulty in breathing and increase fluid retention.
  • Interaction with Disease

    Dosage should be modified for patients with kidney disease, bleeding disorders, decreased platelet count and irregular heart rhythm.
  • Interaction with Food

    There are no negative interactions with food.

Ques: What is GB 29 TOTAL TABLET?

Ans: This drug belongs to a medicine group that contains Mecobalamin, Nortriptyline and Pregabalin as main ingredients present. It is used for curing Neuropathic pain. Dubinor tablet is prescribed to patients that have damaged nerve cells. It decreases pain by protecting nerve fibres.

Ques: What is the use of GB 29 TOTAL TABLET?

Ans: This tablet treats conditions like neuropathic pain and seizures. It is also used as an active Vitamin B12. Dubinor tablet helps to regenerate methionine from homocysteine. It also helps to increase erythrocyte production by promoting nucleic acid synthesis.

Ques: What are the side effects of GB 29 TOTAL TABLET?

Ans: There are some serious side effects of GB 29 Total like Fatigue & uncoordinated body movements. In case of patients having any of the side effects or issues like weight gain, blurred vision or dry mouth.

Ques: For what treatment GB 29 TOTAL TABLET used for?

Ans: GB 29 Total is used to cure neuropathic pain and seizures. It also treats damaged nerve cells and rejuvenate them. This medicine helps to increase erythrocyte production by promoting nucleic acid synthesis.

Ques: How long do I need to use GB 29 TOTAL TABLET before I see improvement of my conditions?

Ans: GB 29 Total takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

Ques: What are the contraindications to GB 29 TOTAL TABLET?

Ans: Contraindication to GB 29. In addition, this medication should not be used if you have the following conditions such as hypomania, lactation, liver disease, narrow-angle glaucoma, peripheral edema, Pphaeochromocytoma, etc.

Ques: Is GB 29 TOTAL TABLET safe to use when pregnant?

Ans: GB 29 Total is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Ques: Will GB 29 TOTAL TABLET be more effective if taken in more than the recommended dose?

Ans: No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as irritability, muscle cramps, fatigue, blurred vision, clumsiness, unable to sleep, memory impairment, sore throat, etc.

Ques: At what frequency do I need to use GB 29 TOTAL TABLET?

Ans: The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person.

Ques: Should I use GB 29 TOTAL TABLET empty stomach, before food or after food?

Ans: GB 29 Total is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

Ques: What are the instructions for the storage and disposal of GB 29 TOTAL TABLET?

Ans: GB 29 Total contains salts that should be stored only at room temperature. Protect it from moisture and light. Keep this medication away from children. You are advised disposing of the expired or unused medication, for avoiding its inadequate effect.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
What are the uses of GB 29 TOTAL TABLET
What are the contraindications of GB 29 TOTAL TABLET ?
What are the side effects of GB 29 TOTAL TABLET ?
Key highlights of GB 29 TOTAL TABLET
What are the substitutes for GB 29 TOTAL TABLET ?
What are the dosage instructions?
How does this medication work?
What are the interactions of GB 29 TOTAL TABLET ?