Dubinor Tablet

Dubinor Tablet is used to treat neuropathic pain & helps the body to produce red blood cells. Being a combination medication containing Methylcobalamin, Nortriptyline, Pregabalin, it is used as a dietary supplement.

Dubinor Tab is a combination of medicine that works through multiple mechanisms. The main active constituents of this medicine are nortriptyline and pregabalin.

Nortriptyline falls under a category of medications called tricyclic antidepressants. Pregabalin is an anticonvulsant & is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia.

Dubinor Tablet also helps in treating diabetic nerve pain, epilepsy, spinal cord injury, restless leg syndrome and generalised anxiety disorder. Dubinor also helps in curing certain mental/ mood disorders.

Dubinor medicine works by binding a certain region of the brain and reduces the pain signals sent out by the damaged nerves of the body. It also prevents megaloblastic or pernicious anaemia that lead to weakness, fatigue, numbness of fingers, toes and problems in thinking.

• Neuropathic Pain

• Allergy

• Abdominal Pain

• Nausea Or Vomiting

• Rapid Weight Gain

• Constipation

• Loss Of Vision Or Blurred Vision

• Dry Mouth

• How long is the duration of effect?

  Dubinor Tablet is eliminated from the body via faeces. However, the duration of action is not clearly established.

• What is the onset of action?

  The peak effect of this tablet is achieved within 3 hours of oral administration.

• Are there any pregnancy warnings?

  Consult your doctor and discuss the potential benefits and risks before taking this medication.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  The excretion of Dubinor Tab in breast milk is not known. Consult your doctor if you are breastfeeding while using this medicine.

• Is It safe with alcohol?

  Alcohol should not be consumed while on this medication.

• Is it safe to drive while on this medicine?

  It is not safe to drive while you are on this medication since it causes drowsiness and dizziness.

• Does this affect kidney function?

  Patients with kidney disease should be cautious while taking this medication. Consult your doctor for alternatives or dosage adjustments.

• Does this affect liver function?

  It is safe for patients with liver disease.

Below is the list of medicines, which have the same composition, strength and form as Dubinor Tablet , and hence can be used as its substitute.

• Nervijen Np Tablet

  Jenburkt Pharmaceuticals Ltd

• Metlin Nt Tablet

  Alteus Biogenics Pvt Ltd

• Nortipan M 1500 Mcg/10 Mg/75 Mg Tablet

  Medley Pharmaceuticals

• Are there any missed dose instructions?

  Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected.

Dubinor is a combination medicine which works through multiple mechanism. Methylcobalamin acts as a cofactor for enzyme methionine synthase, which transfers methyl groups for the regeneration of methionine from homocysteine. In anemia, it increases blood cell production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes. Nortriptyline is a tricyclic antidepressant which blocks the norepinephrine presynaptic receptors which in turn inhibits norepinephrine reuptake. This raises its concentration in the synaptic clefts of the CNS. It also blocks reuptake of serotonin at the neuronal membrane. Pregabalin is a GABA analog and binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Altogether they alleviates the symptoms.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol consumption is not recommended while taking this tablet since it increases drowsiness and calmness.

• Interaction with Medicine

  Certain drugs should be avoided while on this medication like Antidiabetic drugs, benzodiazepines, sedatives and angiotensin-converting-enzyme inhibitors since they cause difficulty in breathing and increase fluid retention.

• Interaction with Disease

  Dosage should be modified for patients with kidney disease, bleeding disorders, decreased platelet count and irregular heart rhythm.

• Interaction with Food

  There are no negative interactions with food.

• Ques : What is Dubinor Tablet?

  Ans : Dubinor belongs to a medicine group that contains Mecobalamin, Nortriptyline and Pregabalin as main ingredients present. It is used for curing Neuropathic pain. Dubinor tablet is prescribed to patients that have damaged nerve cells. It decreases pain by protecting nerve fibres.

• Ques : What is the use of Dubinor Tablet?

  Ans : Dubinor Tablet treats conditions like neuropathic pain and seizures. It is also used as an active Vitamin B12. Dubinor tablet helps to regenerate methionine from homocysteine. It also helps to increase erythrocyte production by promoting nucleic acid synthesis.

• Ques : What are the side effects of Dubinor Tablet?

  Ans : There are some serious side effects of Dubinor medicine like Fatigue & uncoordinated body movements. In case of patients having any of the side effects or issues like weight gain, blurred vision or dry mouth.

• Ques : For what treatment Dubinor Tablet used for?

  Ans : Dubinor Tab is used to cure neuropathic pain and seizures. It also treats damaged nerve cells and rejuvenate them. This medicine helps to increase erythrocyte production by promoting nucleic acid synthesis.

• Ques : How long do I need to use Dubinor Tablet before I see improvement in my condition?

  Ans : Dubinor Tablet should be consumed until the complete eradication of the disease. Thus it is advised to use till the time directed by your doctor. Also if the medication is consumed longer than it was prescribed, it can cause an inadequate effect on the patient's condition.

• Ques : At what frequency do I need to use Dubinor Tablet?

  Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person.

• Ques : Should I use Dubinor Tablet empty stomach, before food or after food?

  Ans : Dubinor Tablet is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

• Ques : What are the instructions for the storage and disposal of Dubinor Tablet?

  Ans : Dubinor Tab contains salts that should be stored only at room temperature. Protect it from moisture and light. Keep this medication away from children. You are advised disposing of the expired or unused medication, for avoiding its inadequate effect.

• Nortriptyline- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/nortriptyline

• Nortriptyline-EMC [Internet]. www.medicines.org.uk. 2017 [Cited 24 April 2019]. Available from:

  https://www.medicines.org.uk/emc/product/4090/smpc

• Methylcobalamin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/methylcobalamin

• METHYLCOBALAMIN- methylcobalamin injection- Daily Med [Internet]. dailymed.nlm.nih.gov. 2015 [Cited 26 April 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=24fd5ca6-b69e-3542-e054-00144ff88e88

• Pregabalin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/pregabalin

• Pregabalin: Uses, Side effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 25 April 2019]. Available from:

  https://www.drugsbanks.com/important-information-about-pregabalin/