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Overview

Dortas-T Injection

Manufacturer: Intas Pharmaceuticals Ltd
Medicine composition: Dorzolamide, Timolol
Prescription vs.OTC: Prescription by Doctor required

Dortas-T Injection is used by doctors to control high pressure that develops in the eyes, as a result of problems like ocular hypertension or open-angle glaucoma. The drug acts as a carbonic anhydrase inhibitor, and reduces the production of fluid and development of eye pressure.

The drug should be avoided if you are allergic to any substance that is present in it, or suffer from kidney issues. Medical professional do not recommend Dortas-T Injection to patients who are already using another type of carbonic anhydrase inhibitor.

Before you start using Dortas-T Injection provide your doctor with a detailed medical history and inform him about any kidney or liver problems, or any particular eye infection or injuries that you have had. Also let him know if you are pregnant or trying to conceive or even nursing a child. Give him a list of all prescribed and over-the-counter drugs that you are currently on as well.

Certain side effects of Dortas-T Injection that one may experience are bad mouth taste, light sensitivity, production of more tears, dryness of the eyes, burning or irritation in the eyes and blurry vision. If these side effects do not go away or become more severe get in touch with your medical provider immediately and seek treatment.

In addition to its intended effect, Dortas-T Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Altered taste
Stinging in the eyes
Burning sensation in eye.
Is It safe with alcohol?
No interaction found
Are there any pregnancy warnings?
Dortas 2% eye drop may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
Does this affect kidney function?
Caution should be advised in patients with severe renal impairment.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Are there any missed dose instructions?
If you miss a dose of Dorzolamide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Will timolol eye drops for glaucoma decrease heart rate and cause heart block or bradycardia in normal subjects.

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
Will timolol eye drops for glaucoma decrease heart rate and cause heart block or bradycardia in normal subjects.
The timolol eye drops for glaucoma decrease heart rate but will not cause heart block or bradycardia in normal subjects.
1 person found this helpful

I am glaucoma patient. It is my right to say that glaucoma start appearing is because I got heart attack. In glaucoma machine I got one portion damaged. Now further timolol and other medicines I use when I felt eye sight problem. Is glaucoma needs daily medicines.

MBBS, MS - Ophthalmology
Ophthalmologist, Delhi
I am glaucoma patient. It is my right to say that glaucoma start appearing is because I got heart attack. In glaucoma...
No glaucoma is a separate entity & is unrelated to myocardial infarction. Cerrtainly, you would be requiring topical drugs to keep your intraocular pressure at a desired range.
1 person found this helpful

Who are at risk Of developing bradycardia from timolol eye drops? Do people having resting pulse rate in the range Of 60-65 are at a risk Of developing heart problems like bradycardia as this medication work by slowing the heart rate?

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
Who are at risk Of developing bradycardia from timolol eye drops? Do people having resting pulse rate in the range Of...
Yes, beta blockers like timolol can drop the blood pressure profoundly, and even cause fainting from low blood pressure and slow heart rate ( bradycardia ). Beta blockers should be avoided in people with chronically low blood pressure.

I am 44 yr old female having Glaucoma in both the eyes having pressure 22-24 despite regularly administering Timolol eye drop suggested by Eye specialist.What should I do.My perimetry test is normal and optic nerve is not affected but all the time heaviness in eyes and headeche sometimes create lot of problem

MBBS, DOMS
Ophthalmologist, Hyderabad
Hi, Glaucoma needs continuous long term followup. You may need one or more eye drops added to timolol, or be prescribed a replacement for it. Any eye drop prescribed, needs to be reviewed for the required efficacy (desired result achieved in you or not) and for any unwanted side effects.

My father is diagnosed with open angle glaucoma. Iop is 21 and 23 .prescribed with timolol eye drops. He has a resting pulse rate Of around 65 per minute. Will the usage Of this drug causes Brady cardia and similar heart problems.

BHMS, MD- Alternative Medicine, Basic Life Support (B.L.S)
Homeopath, Surat
My father is diagnosed with open angle glaucoma. Iop is 21 and 23 .prescribed with timolol eye drops. He has a restin...
There is no such recorded side effect of this drug. You can use it as per your doctor's prescription.
1 person found this helpful

Popular Health Tips

6 Magical Tips to Cope with Migraine Attacks

INSTITUTE OF ALTERNATIVE MEDICINES
Ayurveda, Delhi

6 Magical Tips to Cope with Migraine Attacks

Migraines affect up to 18 percent of women and 6 percent of men in the United States. Today, migraines affect as many as four out of every five people in America.  Doctors are still unraveling the mysteries of migraines. Most doctors believe a combination of things that cause people to have migraines. The causes of migraines range from genetics to neurovascular imbalances in the brain.

Why Do Most People Experience Weather Related Migraines?

It is not entirely clear why some people experience more migraines around the change of weather.  Even though the cause of weather related migraines has not been identified, there are ways to decrease the severity, reduce and prevent migraines from occurring.

In a recent survey by the National Headache Foundation, headache sufferers were given a list of possible causes. They were asked to rank them in terms of what commonly brought on their migraines. Three out of every four respondents said that weather triggered their headache pain.

Specific weather triggers included:

  • Changes in humidity
  • Changes in temperature
  • Storms
  • Extremely dry conditions

Most people have an idea of what causes their migraines, but the real question is what can you do to help reduce the amount of migraines, decrease the severity or prevent the migraines from occurring?   Below are six tips to help you cope and find a solution to preventing your migraines. 

6 Tips on How to Cope With Your Migraines

Tip # 1 – Keep a Diary of Your Migraines:

Keeping a diary is the first step toward finding a solution, so your migraines do not disrupt you and stop you from having a healthy, happy and productive life.  The first step is to try to figure out what triggers your migraines.  One way to do that is to keep a diary of all your migraines.  If you think weather is a reason for your migraines then record any of the common weather and environmental factors that may have initiated your migraines. Keep a detailed diary and bring this diary to your doctor, so your doctor can figure what the best treatment is for you.

In your diary, you should include:

  • What part of the brain do you feel the pain?
  • What does the pain feel like?
  • The time your headache began and when it ended
  • Any changes in the weather, such as storms, high winds, or high humidity
  • Any warning signs – symptoms before the migraine occurred
  • Any treatment you tried, and whether it helped or made the migraine worse

Tip # 2 – Making Changes in Your Daily Regimen:

Making changes in your everyday life can help reduce the number and severity of migraines you are experiencing. Here are some changes you can incorporate into your life that can help improve the number of migraines you are experiencing.

  • Sleep: Make sure you get enough of sleep and try going to sleep around the same time each night.  Interruptions in your sleep schedule, getting too much or too little sleep, can trigger a migraine.
  • Exercise regularly: Research has shown that regular, moderate aerobic exercise may reduce the severity, duration, and number of migraines in many people. Regular exercise also helps control stress, another migraine trigger.
  • Eat regular meals: Eating healthy meals regularly are important to maintain level blood sugar. A drop in blood sugar can trigger a migraine.
  • Drink plenty of water: Make sure you drink plenty of water to avoid dehydration, which can trigger migraine.
  • Limit stress: For many migraine sufferers, stress is plays a big factor. Take time each day to relax. Find something that helps you relax like listening to soothing music, taking short walks, meditating or doing yoga.
  • Try complementary therapies: Try using complementary therapy to help prevent migraines. For example, you may be able to manage stress and prevent migraines through acupuncture, massages and cognitive behavioral therapy.

Tip # 3 – Incorporate Certain Foods into Your Diet:

If you are a migraine sufferer like me, you are constantly looking for prevention ideas. Certain foods can help fight off and prevent migraines.  These foods include:

  • Cayenne: Cayenne peppers are widely recognized as culinary ingredients that add intense heat and flavor to southwest American, Caribbean, Indian and Asian dishes. However, this pepper may also offer healing benefits. Capsaicin, the chemical that gives cayenne peppers their heat, may help reduce blood vessel constriction. This may help prevent rapid blood pressure fluctuations that can trigger migraine headaches.
  • Coffee: When it comes to coffee, caffeine can give you migraine relief. It is a major ingredient in many headache medications. However, if you consume too much, it can actually cause migraines. Moderation is key!
  • Flaxseed and Fish: An anti-inflammatory diet is beneficial to preventing migraines.  Flaxseeds and fish are packed with omega-3s and fiber can actually help prevent migraines.
  • Riboflavin-rich Foods: Riboflavin, also known as vitamin B-2, is one of eight B vitamins necessary for the metabolism of nutrients and protection of your central nervous system. A deficiency of this vitamin may also contribute to headaches, particularly migraines. Adding foods high in riboflavin may help stop recurring migraines by correcting deficiencies. Eggs, avocados, broccoli, romaine lettuce, alfalfa, asparagus, walnuts and mushrooms are abundant sources of riboflavin.
  • Magnesium-rich Foods: About 60 percent of migraine sufferers may have magnesium deficiencies. Magnesium is a trace mineral that may help normalize nerve impulses in your brain that transmit pain signals. This may help stop intense pain associated with migraine headaches. It may also help regulate the production of serotonin, a neurotransmitter chemical that may contribute to sudden changes in blood pressure – a contributing factor of migraines. Increase your magnesium intake by consuming foods such as kale, tofu, lima beans, kelp, garlic, apples, bananas and apricots.

Tip # 4 – Consider Dietary Supplements:

  • Magnesium: This is probably the most important one as it contributes to relaxing the brain blood vessels that cause the pain. Magnesium penetrates cell membranes, including the mitochondria. Some of the best drugs used to treat migraines are calcium channel blockers.
  • Vitamin B2: (riboflavin) – Riboflavin, which is vitamin B2, converts energy from carbohydrates. The riboflavin gives your brain more energy, which makes it less likely to be bothered by migraine triggers.
  • Vitamin B6: Vitamin B6 is needed so the body can properly use serotonin and dopamine. These neurotransmitters are necessary for normal nerve cell communication. Researchers have found lower levels of serotonin in people with migraine headaches. Therefore taking Vitamin B6 may help the body better use these crucial chemicals and it is thought be a key vitamin for migraine aura and a natural remedy for migraines.
  • Vitamin B12 & Folic acid:  Vitamin B-12 supplements may also be effective for migraine relief if taken along with vitamin B6 and folic acid. A study published in “Pharmacogenetics & Genomics” in June 2009 showed that participants who took all three supplements together saw a reduction in migraine headache frequency and the severity of their pain.

Tip # 5 – Consider the Possibilities of Herbal Supplements:

For centuries, many people have used alternative therapies to help or cure common conditions.    Certain herbs have been used to help reduce or prevent migraines.  Some can be just as strong or effective as prescription drugs. Therefore, it is important to remember, if you consider using any type of herbal supplements, consult your doctor first.  Make sure it does not conflict with any medications you are currently taking.   You should not take any herbal supplements or drugs unless your doctor says it is OK and if you are pregnant, you should not take any herbal supplements because it may harm the baby.

Herbal supplements used to reduce and prevent migraines include the following:

  • Alfalfa Leaf
  • Barberry Root
  • Bay Leaf
  • Brazilian Guarana
  • Butterbur
  • Catnip
  • Cayenne
  • Chamomile
  • Dong Quai
  • Evening Primrose
  • Feverfew
  • Ginger Root
  • Green Tea
  • Griffonia Seed
  • Hawthorne Leaf
  • Honeysuckle
  • Kola Nut
  • Lemon Balm
  • Passion Flower
  • Peppermint Leaf
  • Valerian Root
  • White Willow Bark
  • Wintergreen
  • Wood Betony

Tip # 6 – Prescription Medications:

Not all experts would recommend using medication to prevent temperature-change-related migraines.  However, if you have tried natural, holistic and alternative therapies to try to eliminate your migraines and nothing seems to be effective then you should focus on other alternatives such as prescription medications specifically made to help people suffering from migraines.

Below are some prescription medications for patients suffering from migraines:

  1. Antiepileptic drugs: Certain medications used to control seizures are also effective for preventing migraines as well. These drugs may work by calming the neurons in the brain. Neuron “hyperexcitability” plays a role in migraine and epilepsy. Up to 20% of people with epilepsy also suffer from migraines including myself.  Anti – seizure medications that help migraines include:
    1. Depacon (valproate)
    2. Depakote (divalproex)
    3. Topiragen, Topamax (topiramate)
  2.  Beta-blockers: These medications are frequently used to treat high blood pressure and heart disease. It is not clear how they help prevent migraines. Nevertheless, beta-blockers improve the blood flow and this may be significant reason why beta-blockers help prevent migraines.  Beta-blockers that have been proven effective for the prevention of migraines include:
    1.  Blocadren (timolol)
    2. Inderal, Innopran XL (propranolol)
    3. Lopressor, Toprol XL (metoprolol)
  3. Antidepressants: These medications affect the level of the brain chemical serotonin. Research has shown that Elavil (amitriptyline) and Effexor (venlafaxine) work well for preventing migraines.
7 people found this helpful

Table of Content

About Dortas-T Injection
When is Dortas-T Injection prescribed?
What are the side effects of Dortas-T Injection?
Key highlights of Dortas-T Injection
What are the dosage instructions?
What are the interactions for Dortas-T Injection?