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Overview

Deferoxamine

Prescription vs.OTC: Prescription by Doctor required

Deferoxamine is used in treating chronic iron overload and acute iron poisoning especially in small children which is caused by anemia and requires frequent blood transfusions. Deferoxamine is an iron-chelating agent. Deferoxamine works by binding itself to excess iron in the blood so that it can be removed from the body. You should not take Deferoxamine is you have an allergies to Deferoxamine and if you have severe kidney problems and or you are unable to urinate.

Some common side effects of Deferoxamine include: blurred vision or any sudden problems related to your vision, a change in your fingernail colour to a bluish colour, seizures, difficulty in breathing or fast breathing, a sudden change in your heartbeat rate or fast heartbeat, hearing problems, redness or flushing of the skin. Other side effects include diarrhea, headache, mild stomach pain, nausea, stomach upset. As with any medication you should tell your doctor about all the medication you are on, the allergies you have etc. Some precautions include: pregnancy, if you depend on dialysis, if you take vitamin C, if you have a certain disease that increases the amount of iron your body absorbs from your diet.

iron overload
transfusion dependent thalassemia
In addition to its intended effect, Deferoxamine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Flushing (sense of warmth in the face
ears
neck and trunk)
Rash
Decreased blood pressure
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Defrijet 500mg tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
Patients may experience dizziness or other nervous system disturbances , and they should avoid driving or operating machinery.
Does this affect kidney function?
There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Are there any missed dose instructions?
If you miss a dose of Deferoxamine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Below is the list of medicines, which contains Deferoxamine as ingredient
Sun Pharmaceutical Industries Ltd
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.

Popular Health Tips

Thalassemia in Children - 4 Ways to Treat it!

MBBS, DCH
Pediatrician, Gwalior
Thalassemia in Children - 4 Ways to Treat it!

Thalassemia is a type of a disease, resulting in the abnormal production of hemoglobin in the blood. Hemoglobin stimulates oxygen circulation all over the body. Therefore, a dip in the hemoglobin count can lead to anemia, a disease inducing weakness as well as fatigue. Acute anemia can take a toll on the organs and ultimately cause death.

Severe thalassemia in children yields symptoms, such as dark urine, abdominal swelling, slow growth, jaundice, a pale appearance and deformed skull bones. Diarrhea, frequent fevers and eating disorders are also common.

Treatment:

  1. Blood transfusions: Regular blood transfusion is the only treatment needed for beta thalassemia aiming to keep sufficient Hb level to avoid long-term complications, though bone marrow transplant is radical cure for the disease.
  2. Iron chelation therapy: The hemoglobin in the red blood cells is rich in iron-protein that gets deposited in the blood with regular blood transfusion. This condition is known as iron overload as it damages heart, liver and various parts of the body. Iron chelation therapy is used to prevent this damage as it helps to remove the excess iron from the body.  Deferoxamine and Deferasirox are two such medicines used for this therapy.
  3. Folic acid supplements: Folic acid being a B vitamin produces healthy red blood cells and is therefore recommended as a substitute for the above procedures.
  4. Transplant of blood and marrow stem cell: A blood and a marrow (a substance within the cavities of bones where blood cells are produced) transplant replaces the faulty stem cells with healthy ones contributed by a donor.

Thalassemia in Children - 4 Ways to Treat it!

MD - Paediatrics, MBBS
Pediatrician, Jaipur
Thalassemia in Children - 4 Ways to Treat it!

Thalassemia is a type of a disease, resulting in the abnormal production of hemoglobin in the blood. Hemoglobin stimulates oxygen circulation all over the body. Therefore, a dip in the hemoglobin count can lead to anemia, a disease inducing weakness as well as fatigue. Acute anemia can take a toll on the organs and ultimately cause death.

Severe thalassemia in children yields symptoms, such as dark urine, abdominal swelling, slow growth, jaundice, a pale appearance and deformed skull bones. Diarrhea, frequent fevers and eating disorders are also common.

Treatment:

  1. Blood transfusions: Regular blood transfusion is the only treatment needed for beta thalassemia aiming to keep sufficient Hb level to avoid long-term complications, though bone marrow transplant is radical cure for the disease.
  2. Iron chelation therapy: The hemoglobin in the red blood cells is rich in iron-protein that gets deposited in the blood with regular blood transfusion. This condition is known as iron overload as it damages heart, liver and various parts of the body. Iron chelation therapy is used to prevent this damage as it helps to remove the excess iron from the body.  Deferoxamine and Deferasirox are two such medicines used for this therapy.
  3. Folic acid supplements: Folic acid being a B vitamin produces healthy red blood cells and is therefore recommended as a substitute for the above procedures.
  4. Transplant of blood and marrow stem cell: A blood and a marrow (a substance within the cavities of bones where blood cells are produced) transplant replaces the faulty stem cells with healthy ones contributed by a donor.
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