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Cosmelite Cream

Manufacturer :  Adcock Ingram Healthcare Pvt Ltd
Medicine Composition :  Hydroquinone, Mometasone, Tretinoin
Prescription vs OTC : Prescription by Doctor not required

About Cosmelite Cream

Cosmelite Cream is primarily prescribed to patients to treat melasma. It is a combination of Hydroquinone, Mometasone, and Tretinoin helpful in treating skin related problems.It helps in skin renewal quickly. The other functions are used to reduce scars and dark circles.

Cosmelite Cream is very useful in reducing the colour of the skin and removing any dark spots like freckles, age spots and other skin discolouration associated with pregnancy, skin trauma, eczema, birth control pills or hormone replacement therapy. It functions as a skin-bleaching agent which works by restricting an enzyme reaction in the applied skin cells.

Mild burning, redness, stinging and dryness may occur as side effects to using this medicine. Serious side effects which may occur include skin cracking, blistering and blue-black darkening of the skin.

Before using this medicine, discuss with your doctor your medical history, especially if you have asthma, other skin conditions like eczema or psoriasis. Do not use the medicine if you have had allergic reactions to it.

Melacare Cream is recommended to apply this medicine to the affected areas of skin, generally twice every day or as directed by your doctor. Avoid its contact with your eyes, nose or mouth. Avoid tanning booths, prolonged sun exposure and sunlamps. Use this medication regularly to get the most benefit from it.

Patient must use this medicament in the prescribed dose and manner. You must wash your hands and skin to which it is to be applied before applying this medicament on over it. Check the label for directions is advised before using it. This medicament is only for external use.

The cream is also used to treat pimples and acne in some cases. It works by inhibiting the synthesis of melanin which is the cause for the dark pigmentation of the skin, in addition to this it softens the skin when promotes a reduction in scars.

It also decreases the inflammation of the skin which reduces the redness and itching in the skin. The cream should be used with sunscreen for better noticeable effects. The cream should be used once a day, preferably at night. Apply and massage gently till the cream is fully absorbed.

The main drawback of this medication is that once the patient stops using this medication the skin starts to lose color and deteriorates. The medication is not at all recommended for lactating or expecting mothers as it poses a threat for the baby.

    What are the uses of Cosmelite Cream

    • Melasma

    What are the contraindications of Cosmelite Cream ?

    • Hypersensitivity

    What are the side effects of Cosmelite Cream ?

    • Skin Thinning

    • Contact Dermatitis

    • Scaling, Burning, Redness, And Swelling Of Skin

    • Drying And Cracking Of Skin

    • Irritation

    • Itching

    • Redness

    Key highlights of Cosmelite Cream

    • How long is the duration of effect?

      The duration of the effect is seen is a few days, but it stops once the medication has been stopped.

    • What is the onset of action?

      Initial improvement maybe seen in a couple of weeks, though full results usually show up aft 3-4 months with everyday use.

    • Is it habit forming?

      No habit forming tendencies were reported, however if you stop medication the symptons will resurface and inly get worst..

    • Is It safe with alcohol?

      With alcohol, no interactions have been found or established.

    • Are there any pregnancy warnings?

      No recommended during pregnancy as it shows adverse effects on the foetus, please consult your doctor before you start medication.

    • Are there any breast-feeding warnings?

      This cream is not safe for lactating mothers as the cream seems to be toxic for the baby. Not recommended for women who are breast feeding.

    • Is it safe to drive while on this medicine?

      Yes, it is safe to drive while using this medication

    • Does this affect kidney function?

      No, this does not affect kidney functions.

    • Does this affect liver function?

      No, this does not affect liver functions

    What are the substitutes for Cosmelite Cream ?

    Below is the list of medicines, which have the same composition, strength and form as Cosmelite Cream , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If the time of the missed dose is not very much then you can apply the medication, else you can skip the does and carry on normally the next time. Do not over apply to make up for the missed dose.

    • Are there any overdose instructions?

      If you over apply the cream simply wipe off the excess. If incase you consume it, then report it to the nearest emergency room.

    How does this medication work?

    This medicament is a skin lightening agent for topical application which inhibits tyrosinase enzyme, which is an important enzyme in the biosynthesis of melanin pigments. Inhibition of tyrosinase thus inhibits the production of melanin pigments, leading to skin lightening.

      What are the interactions of Cosmelite Cream ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

      • Interaction with Alcohol

        With alcohol, no interactions have been found or established.

      • Interaction with Medicine

        The cream does not react very well with Resorcinol, Salicylic acid and sulfur. The interaction maybe sever and is not recommended.

      • Interaction with Disease

        It is not advised to use this medication if you are allergic to any of the ingredients. If you have liver infections, dehydration.

      • Interaction with Food

        No interactions with food have been found or established.

      FAQs about Cosmelite Cream

      • Ques : What is Cosmelite cream?

        Ans : Cosmelite is an ointment which has Hydroquinone Topical, Mometasone Topical and Tretinoin Topical as active elements present in it. This ointment performs its action by restricting the enzyme tyrosinase, showing anti-inflammatory and antipruritic activities, increasing the turnover of follicular epithelial cells. This medication is used to treat conditions such as Allergen, Psoriasis, Skin discolorations associated with pregnancy, Allergic reactions, Nasal polyps, Skin inflammation, Nose allergies, Eczema, Skin itching, White blood cells cancer, etc.

      • Ques : What is the use of Cosmelite cream?

        Ans : Cosmelite is a medication, which is used for the treatment and prevention from conditions and symptoms of diseases like Melasma, Acne vulgaris, Acne, Age spots, Lightens light brown color patches on skin, Dermatitis of the scalp, Dry, rough patches and tiny bumps on skin, Wrinkles, Allergen, Psoriasis, Skin discolorations associated with pregnancy. Apart from these, it can also be used to treat conditions like Allergic reactions, Nasal polyps, Skin inflammation, Nose allergies, Eczema, Skin itching, White blood cells cancer, etc. The patient should inform the doctor about any ongoing medications and treatment before using Cosmelite cream to avoid undesirable effects.

      • Ques : What are the side effects of Cosmelite cream?

        Ans : Cosmelite cream is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of this cream are as follows: Depigmentation, Acne, Hyper or hypopigmentation, Skin dryness, Blistering, Increased hair growth on the face, Feeling of heat, Skin rash, Skin irritation, Exogenous ochronosis, Skin pain, Pruritus, Pharyngitis, Erythema. It is a list of possible side-effects which may occur due to the constituting ingredients of Cosmelite cream.

      • Ques : Can Cosmelite Cream be used for melasma and acne vulgaris?

        Ans : Yes, Cosmelite is an ointment which can be used for the conditions such as melasma and acne vulgaris. Do not apply Cosmelite cream for above-mentioned conditions without consulting first with your doctor. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use cosmelite cream before I see improvement in my condition?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 week to 1 months, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

      • Ques : At what frequency do I need to use cosmelite cream?

        Ans : This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

      • Ques : Should I use cosmelite cream empty stomach, before food or after food?

        Ans : This medication is commonly used by applying it to the affected area. As this medication is for external use, the action of salts involved in this medication does not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use.

      • Ques : What are the instructions for the storage and disposal of cosmelite cream?

        Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.


      • Hydroquinone- Drug Information Portal [Internet]. 2019 [Cited 25 April 2019]. Available from:

      • Mometasone- Drug Information Portal [Internet]. 2019 [Cited 25 April 2019]. Available from:

      • Tretinoin- Drug Information Portal [Internet]. 2019 [Cited 25 April 2019]. Available from:

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Rohini DhillonMBA( CHA), MBBS, PGDMCHGeneral Physician

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