Tretinoin

Tretinoin is prescribed to patients with severe acne problems. The drug effectively treats acne and reduces the amount of pimples that tend to develop, while healing pimples that have already developed on the body. The group of medicines that the drug belongs to is known as retinoids. The drug affects skin cell growth in the body regulating the amount of pimples that crop up.

The drug is mostly available in the form of a topical cream. Make sure that your hands are clean and dry before you apply the cream. Clean the area of the body affected by pimples with a light cleanser and pat it dry. Apply a light layer of the medication daily just before bed time or as per directions given by your doctor. You can also use cotton or gauze for equal application of the cream. Tretinoin is meant to be applied to the skin only. Do not apply the medicine on a cut or scratch. Also avid application on the inner lip or mouth.

Keep the drug away from children. Also ensure that it does not get into the eyes. If it does rinse your eyes with water until the irritation stops. If the irritation persist call your doctor and seek further advice.

Side effects commonly occur when you take any medication of drug. In the case of Tretinoin you may experience a slight sting during the process of application on the skin. Other common side effects include scaling, dryness of the skin, irritation or redness and temporary increase in acne. These symptoms will last for about a couple of weeks after you start using Tretinoin. They generally decrease and eventually go away with pro-long use. If you do experience heavy skin dryness, you can use a mild moisturizer.

The drug increase sensitivity to light, thus ensure that you have sunscreen on when you go out during the day. Also put a hat on and wear goggles to protect yourself from bright sunlight.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Dermatologist before using this medicine.

• Acne Vulgaris

  This medicine is used to prevent and treat pimples. It also reduces the occurrence of new pimple breakout and promotes the healing of the skin.

• Wrinkled And Rough/Mottled Skin

  This medicine is used for management of wrinkles, rough patches, and patchy skin color associated with excess UV/sunlight exposure. It is mostly used in combination with other medicines.

• Acute Promyelocytic Leukemia

  This medicine is also used orally under specific circumstances to treat a cancer of the blood where the affected cells fail to mature properly.

• Allergy

  This medicine is not recommended for use if you have a known history of allergy to tretinoin/isotretinoin/retinoids or any other component present in the dosage form.

• Skin Irritation

• Burning Or Tingling Sensation Of Skin

• Red Spots On Skin

• Peeling And Blistering Of Skin

• Patchy Appearance Of Skin

• Photosensitivity Of Skin

• Nausea Or Vomiting

  Oral Form

• Fever With Body Pain

  Oral Form

• Dry Mucous Membrane

  Oral Form

• Blood Cell Disorder

  Oral Form

• Difficulty In Breathing

  Oral Form

• Dizziness

  Oral Form

• Coffee Colored Vomit

  Oral Form

• Hearing Loss

  Oral Form

• Unusual Bleeding

  Oral Form

• How long is the duration of effect?

  The time duration for which this medicine remains effective is not clinically established.

• What is the onset of action?

  The effect of this medicine can be observed within 2-4 weeks of topical application.

• Are there any pregnancy warnings?

  Use of this medicine by pregnant women is not recommended. Use appropriate contraception and avoid getting pregnant while using this medicine. Contact your doctor and discuss the risks if a pregnancy is suspected.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use by women who are breastfeeding. It can be used if the potential benefits outweigh the risks involved with use. You should not breastfeed while the topical form of this medicine is applied.

• Missed Dose instructions

  Apply the missed dose as soon as you remember. If it is almost time for the next scheduled dose then missed dose application can be skipped. Contact your doctor immediately if you miss an oral dose of this medicine.

• Overdose instructions

  Chances of an overdose with a topical application are very less. However, if the medicine is consumed orally then overdose may happen. Contact your doctor immediately in case of an oral overdose.

• India

• United States

• Japan

Below is the list of medicines, which contains Tretinoin as ingredient

• Elosone Ht Cream

  Leeford Healthcare Ltd

• Twinkle Cream

  Austro Labs

• Htm Cream

  Eskon Pharma

• Melanorm-Ms Cream

  Unimarck Healthcare Ltd

• Getlite Cream

  Glenmark Pharmaceuticals Ltd

• Melacare Cream

  Ajanta Pharma Ltd

• U-B Fair Cream

  Torque Pharmaceuticals Pvt Ltd

• Retop A 0.012% W/W Gel

  Dermo Care Laboratories

• Melapik Plus Cream

  KLM Laboratories Pvt Ltd

• Cosmelite Cream

  Adcock Ingram Healthcare Pvt Ltd

Tretinoin works by binding to alpha, beta, and gamma retinoic acid receptors (RARs) thus activating them. This produces changes in the gene expression that leads to decreased cell multiplication, inhibition of tumoriogenesis and cell differentiation.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Disease

  Eczema

  This medicine should not be used if you are taking medicine for eczema or suffer from a skin abrasion.

  Sunburn

  Use of this medicine on the sunburnt skin should be avoided. Your doctor may prescribe an alternate medicine that is better tolerated.

• Interaction with Alcohol

  Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Food

  Food

  Information not available.

• Interaction with Medicine

  Tetracycline

  The oral form of tretinoin should not be used with tetracycline or other antibiotics belonging to the same category. Your doctor will determine the best course of treatment in such cases.

  Benzoyl Peroxide (Topical)

  Report the use of either of the medicine to the doctor. Your doctor may determine the best course of treatment. Do not stop the use of any medicine without consulting your doctor.

  Salicylic acid (Topical)

  Report the use of either of the medicine to the doctor. Your doctor may determine the best course of treatment. Do not stop the use of any medicine without consulting your doctor.

  Methoxsalen

  Report the use of either of the medicine to the doctor. Your doctor may determine the best course of treatment. It is advised to take appropriate precautionary measures while stepping out into sunlight while using these medicines together.