Li-Fraumeni Syndrome is a rare kind of hereditary disorder that is also called autosomal dominant and puts the individual at a higher risk of cancer. Symptoms of this disorder are linked to germline mutations of the p53 tumor suppressor gene and usually cause cancer. These mutations are inherited and accompanied with regular cancer symptoms like lymph nodes swelling, pain, loss of weight, etc. in later stages.
HOW IS LI-FRAUMENI SYNDROME DIAGNOSED?
An oncologist would diagnose a patient as having Li-Fraumeni syndrome if they or any of their family members or relatives have been diagnosed with a sarcoma before the age of 45 years.
HOW IS LI-FRAUMENI SYNDROME TREATED?
Early treatment of Li-Fraumeni Syndrome can cure the disease and in most of the cases, Li-Fraumeni Syndrome is treated by a radiation therapy, surgery or chemotherapy.
DID YOU KNOW?
The condition is named after two American physicians, Frederick Pei Li and Joseph F. Fraumeni, Jr., who first recognized the syndrome after reviewing the medical records and death certificates of 648 childhood rhabdomyosarcoma patients.