Liddle syndrome is an inherited disorder, that causes hypertension or high blood pressure in patients at an early age. Individuals with this syndrome would experience muscle weakness, constipation and heart palpitations. The low levels of potassium could cause the pH of the blood to increase.
HOW IS LIDDLE SYNDROME DIAGNOSED?
Evaluating a child with persistent high blood pressure requires testing of the blood electrolytes as well as aldosterone level. A genetic study of ENaC sequence can help in identifying the genetic mutations that can cause the condition.
HOW IS LIDDLE SYNDROME TREATED?
A diet low in sodium is advised to patients with this disorder. Diuretics such as amiloride and medicines for hypertension would be prescribed.
DID YOU KNOW?
The Liddle’s Syndrome has been named after Dr. Grant Liddle, who was an American endocrinologist and discovered the disease at Vanderbilt University, in 1963.