This medication is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Omeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.
Zosec D Capsule is a combination of Domperidone and Omeprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.
It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.
The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.
This medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.
You are advised not to take Zosec D Capsule if you have the following conditions:
- An allergy to Zosec D Capsule or any other ingredient of this medicine
- Bleeding problems or blockage in your stomach or in the intestine
- Tumour in the pituitary gland
- Cardiac disease
- Incorrect levels of magnesium, potassium or calcium in the blood
- Severe/moderate liver impairment
The primary use of this medication is as follows:
Gastroesophageal Reflux Disease
Tumor Of Pituitary GlandDomperidone is not recommended for use in people having tumor of the pituitary gland.
Heart DiseasesDomperidone is not recommended for use in people having an active heart disease like Congestive Heart Failure.
How long is the duration of effect?The effect of this medicine lasts up to 6 hours.
What is the onset of action?The peak effect of this medicine can be observed within 30 to 60 minutes of administration.
Are there any pregnancy warnings?This medicine is not recommended for use in pregnant women unless the potential benefits outweigh the risks involved. The effect of this medicine on the fetus is not clearly established and hence you are advised to consult a doctor before taking this medicine.
Is it habit forming?No habit forming tendencies were reported.
Are there any breast-feeding warnings?This medicine is not recommended for use by breastfeeding mothers as there is a risk of side effects on the infant. You are advised to consult your doctors and consider the potential benefit and risks before consuming this medication.
Are there any missed dose instructions?Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.
Are there any overdose instructions?Contact your doctor if an overdose is suspected. Symptoms of overdose may include drowsiness, agitation, and convulsions and may be more prevalent in infants and children. Immediate medical attention including gastric lavage may be required in severe cases.
This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
AlcoholInteraction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
LabThe patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.
Interaction with Medicine
Interaction with Disease
Kidney DiseaseZosec D Capsule should be used with caution if you are suffering from impaired kidney function. Suitable dose adjustment and safety monitoring is advised, especially if the impairment is severe.
Intestinal DisordersZosec D Capsule should be used with extreme caution in people having serious intestinal problems like internal bleeding, an obstruction or perforation of the stomach and intestine. Use of an alternate medicine is advised in such cases.
Interaction with Food
FoodInformation not available.
Ques: What is Zosec D Capsule used for?
- GRD (gastroesophageal reflux disease)
- Erosive esophagitis
- Gastro-duodenal ulcers
- Zollinger-ellison syndrome
Ques: Is Zosec D Capsule safe during pregnancy?
Ques: What is the best time of day to take Zosec D Capsule?
Ques: Is Zosec D Capsule safe while breastfeeding?
Ques: How long do I need to use Zosec D Capsule before I see improvement in my condition?
Ques: At what frequency do I need to use Zosec D Capsule?
Ques: What are the instructions for the storage and disposal of Zosec D Capsule?
Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 27 February 2020]. Available from:https://druginfo.nlm.nih.gov/drugportal/name/domperidone
Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 27 February 2020]. Available from:https://www.drugbank.ca/drugs/DB01184
Omeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 27 February 2020]. Available from:https://druginfo.nlm.nih.gov/drugportal/name/omeprazole
Omeprazole- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 27 February 2020]. Available from:https://www.drugbank.ca/drugs/DB00338
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