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Tramadol

Prescription vs.OTC: Prescription by Doctor required
Last Updated: March 20, 2019

An opioid agonist, Tramadol works as a pain reliever, providing relief from both moderate and severe pain. Similar to endorphins, it binds to the receptors in your body. These receptors will decrease the pain messages that your body generally sends to the brain when you are in pain. The medicine has to be taken orally and is available in three forms - an immediate-release taablet, an extended-release tablet and a capsule. The immediate-release tablet releases into the blood stream at once whereas the extended-release tablets release gradually over time. The medicine can be taken as a combination therapy, where you take it along with other medications for your treatment.

Tramadol works as a pain reliever, used in the treatment of both moderate and severe pain. Being a controlled substance, it must be taken under the close supervision of a doctor. It belongs to a drug group which is known as opioid agonists. The medicine works by bringing a change in the process of how the brain senses pain. It binds to the receptors that decrease the pain messages sent by the body to your brain, thus decreasing the amount of pain that you experience. The medicine is available in three forms, immediate-release (released immediately in blood) tablet, and extended-release (gradually released in blood) tablet and capsule.

Your doctor will decide the dosage of Tramadol and ensure that you follow the instructions. You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it in the same way every day. The capsule must be swallowed wholly, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one. Overdose of Tramadol can have severe side effects including extreme drowsiness, fainting, slow breathing or heart rate and cold/clammy skin.

You must avoid taking Tramadol if you have an allergy to it or any of the ingredients in it, stomach or intestinal blockage, consumed alcohol recently and if you are under narcotic medications. Your doctor must be informed about whether you have a history of metabolic disorders, alcohol addiction and epilepsy. You must also inform the doctor about any prescription of antibiotic and antifungal medicines. The common side effects of Tramadol are headache, nausea, vomiting, dizziness, constipation, sweating, dry mouth and feeling less energetic. However, there can be some serious side effects too that will require immediate medical attention:

You must strictly avoid alcohol when you are taking Tramadol, as there can be fatal side effects when these two things are combined, at times even resulting in death. Ensure to check all food labels and other medicines to confirm that you are not consuming alcohol in any way.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Internal Medicine Specialist before using this medicine.

Tramadol is used in the treatment of schizophrenia. Delusions, hallucinations, reduced speaking are some of the symptoms of schizophrenia.
Tramadol is used in the treatment of bipolar disorder. Unusual shifts in the mood like hyperactivity and tiredness are some of the symptoms of bipolar disorder
Tramadol is used in the treatment of depression. Feeling sad, irritable and devoid of energy are some the symptoms of depression.
Avoid taking this medicine if you have a known allergy to Tramadol or other antipsychotics.
In addition to its intended effect, Tramadol may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Dizziness

Major Common

Chills

Major Common

Confusion

Major Common

Blurred vision

Major Less Common

Loss of balance control

Major Less Common

Difficulty or painful urination

Major Less Common

Dry skin

Major Rare

Irregular menstrual periods

Major Rare

Loss of appetite

Major Rare

Weight gain

Major Rare

Constipation

Minor Common

Headache

Minor Common

Acid or sour stomach

Minor Common

Decreased appetite

Minor Less Common

Sneezing

Minor Less Common

How long is the duration of effect?

The effect of this medicine lasts for a duration of 18 hours for an immediate release tablet and 21 hours for an extended release tablet.

What is the onset of action?

The peak effect of this medicine is observed in 1.5 hours for an immediate release tablet and 6 hours for an extended release tablet.

Are there any pregnancy warnings?

This medicine is not recommended for pregnant women. Use only if clearly needed when no safer alternative is available.

Is it habit forming?

No habit forming tendency has been reported

Are there any breast-feeding warnings?

This medicine is known to be excreted through human breast milk. It is not recommended for breastfeeding women. Use only if clearly needed when no safer alternative is available. Monitoring of undesired effects like drowsiness and delayed developmental milestones is necessary.

Are there any missed dose instructions?

Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Are there any overdose instructions?

Seek emergency medical treatment or contact the doctor in case of an overdose.

India

United States

Japan

Below is the list of medicines, which contains Tramadol as ingredient
Abbott Healthcare Pvt. Ltd
Abbott Healthcare Pvt. Ltd
Abbott Healthcare Pvt. Ltd
Sun Pharma Laboratories Ltd
Unichem Laboratories Ltd
Euphoric Pharmaceuticals (P) Ltd
Nippon Seiyaku Pvt Ltd
Anthus Pharmaceuticals Pvt Ltd.
Zydus Cadila
Zydus Cadila
Comed Chemicals Pvt Ltd
Modi Mundi Pharma Pvt Ltd
Win-Medicare Pvt. Ltd
Tidal Laboratories Pvt Ltd
Glaxo SmithKline Pharmaceuticals Ltd
Edura Pharmaceuticals Pvt Ltd
Apex Laboratories Pvt Ltd
Pulse Pharmaceuticals
Tramadol acts on certain specific pain receptors in the brain and inhibits the reuptake of norepinephrine, serotonin. It also enhances the release of serotonin thereby changing the perception and response to pain
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Dementia

Major
This medicine is not recommended in the patients with dementia-related psychosis as it increases the risk of heart diseases like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.

Interaction with Alcohol

Acute Alcohol Intoxication

Major
Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving or operating machinery.

Interaction with Lab Test

Lab

Information not available.

Interaction with Food

Food

Information not available.

Interaction with Medicine

Tramadol

Major
Tramadol may increase the risk of seizures when taken with Tramadol. This interaction is more likely to happen in the elderly population, and in the patients suffering from head injury. Inform the doctor if you are on either of the medicines. An alternate medicine should be considered based on the clinical condition under the doctor's supervision.

Ketoconazole

Major
Azole antifungal agents like Ketoconazole and Itraconazole should be avoided when you are Tramadol due to the risk of increased concentrations of the medicine in the body which may cause dizziness, dry mouth, and irregular heart beats. Inform the doctor if you are receiving these medicines when you are prescribed with Tramadol and dose adjustments or an alternative medicine should be considered based on the clinical condition.

Metformin

Moderate
The desired effect of antidiabetic agents may not be achieved when taken with Tramadol. Regular monitoring of blood glucose levels is necessary. Inform the doctor if you develop any symptoms like excessive thirst, increased in the frequency of urination. Dose adjustments are to be made based on the clinical condition.

Antihypertensives

Moderate
You may experience hypotensive effects like dizziness, lightheadedness if these medicines are used together. Regular monitoring of blood pressure is necessary. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Why does it hurt so much more at night in my lower back when I'm taking tramadol?

BPTh/BPT
Physiotherapist, Kota
Why does it hurt so much more at night in my lower back when I'm taking tramadol?
Back pain or HIP PAIN k liye back isometrics exercise kijiye or hot fragmentations kijiye. For word bandings mat kijiye. Long time ek hi positins m mat rahiye. Breegings exercise bilateral or single leg rotation kijiye phle without weight kijiye f...
1 person found this helpful

My penis size is getting small due to side effects of the tramadol. What should I do?

BHMS, DEMS
Homeopath, Pune
My penis size is getting small due to side effects of the tramadol. What should I do?
Increasing penis length, girth and enhancing overall appearance is quite possible. This is because the male organ consists of muscles and no bones. As you can develop your biceps, muscles can also be developed present in penis. However, for this, ...
3 people found this helpful

Hello doctor one of my friend is addicted to tramadol injection. Please tell me what can be given to him instead of tramadol injection to calm him down.and how can he withdraw that habit.

MD - Psychiatry
Psychiatrist, Chennai
Hello doctor one of my friend is addicted to tramadol injection. Please tell me what can be given to him instead of t...
He needs to be treated by a psychiatrist as opioid withdrawal is not that easy. The alternative medications need to be carefully dosed under supervision and is not available in the general medical store.
1 person found this helpful

I have tremendous amount of pain in my legs whether it's the nerves or muscle I don't know I take daily 2 tramadol tab to relieve pain suggest me a better medicine than tramadol.

MPT, BPT
Physiotherapist, Noida
I have tremendous amount of pain in my legs whether it's the nerves or muscle I don't know I take daily 2 tramadol ta...
Avoid Squatting- Avoid sitting Cross legged Contrast Fomentation (Hot and Cold). Quadriceps strengthening exercises-

I want to leave tramadol but when I don't have tramadol body pain and I feel like no power in body. Could not sleep. Suggest me what should I do and which is the best doctor.

BHMS
Homeopath, Faridabad
I want to leave tramadol but when I don't have tramadol body pain and I feel like no power in body. Could not sleep. ...
Hi, taking pain-killer like tramadol is not the solution for the pain. So, it's very important to know the cause of body pains in your case. As simple nutritional deficiency can cause general weakness and body-pains. Get the thorough check-up done...
3 people found this helpful

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Table of Content
About Tramadol
When is Tramadol prescribed?
What are the contraindications of Tramadol ?
What are the side effects of Tramadol ?
Key highlights of Tramadol
What are the dosage instructions?
Where is the Tramadol approved?
Medicines containing Tramadol
How does medicine works?
What are the interactions for Tramadol ?