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Sompraz D 40 Capsule Sr

Manufacturer: Sun Pharmaceutical Industries Ltd
Medicine composition: Domperidone, Esomeprazole
Prescription vs.OTC: Prescription by Doctor not required
Last Updated: February 17, 2020

This medication is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Esomeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Sompraz D 40 Capsule Sr is a combination of Domperidone and Esomeprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

This medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Sompraz D 40 Capsule Sr if you have the following conditions:

  • An allergy to Sompraz D 40 Capsule Sr or any other ingredient of this medicine
  • Bleeding problems or blockage in your stomach or in the intestine
  • Tumour in the pituitary gland
  • Cardiac disease
  • Incorrect levels of magnesium, potassium or calcium in the blood
  • Severe/moderate liver impairment

The medication can treat the below provided problems:

  • Gastro-Esophageal Reflux Disease (Gerd)

  • Peptic Ulcer

  • Allergy

  • Tumor Of Pituitary Gland

  • Heart Diseases

Here are some of the possible side effects of this medication:

  • How long is the duration of effect?

    The effect of this medicine can be observed in 30 to 60 minutes after the intake.

  • What is the onset of action?

    The peak effect of this medicine can be observed within 30 to 60 minutes of administration.

  • Are there any pregnancy warnings?

    There have not been any pregnancy warnings for the medicine, but it should be taken only after consulting a doctor.

  • Is it habit forming?

    It is said that no habit-forming tendencies have been observed on upon the intake of this medicine.

  • Are there any breast-feeding warnings?

    It is not recommended to take this medicine while breastfeeding as because it might have adverse effects on the infant. Consult your doctor before consumption of this medication.

  • Is It safe with alcohol?

    It is unknown whether the medicine is safe with alcohol or not. However, it is recommended to consult a doctor before consuming alcohol.

  • Is it safe to drive while on this medicine?

    The medicine may cause sleepiness after the intake of it, so drive upon your own discretion keeping in mind the above.

  • Does this affect kidney function?

    No effects on the kidney have been observed upon the intake of this medicine.

  • Does this affect liver function?

    There is usually no effect on the liver function, but if there is any symptoms of the liver disease observed, then it should be reported to a doctor.

Below is the list of medicines, which have the same composition, strength and form as Sompraz D 40 Capsule Sr , and hence can be used as its substitute.

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  • Are there any missed dose instructions?

    The missed dose should be taken as soon as possible and in case by then it is already time to take the other dose, then the missed dose should be skipped.

  • Are there any overdose instructions?

    Overdose of any medicine should be avoided completely, however, in case of any such situation a doctor should be contacted at the earliest.

This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Disease

    Do not use this drug if you are suffering from Liver Disease, Osteoporosis and Hypomagnesemia.

  • Interaction with Lab Test

    The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.
  • Interaction with Alcohol

    No interactions with alcohol have been noted for this medicine. However, consult a doctor before consuming this medicine along with alcohol.

  • Interaction with Food

    No interactions with food has been noted either for this medicine. Consult a doctor in any case otherwise.

  • Interaction with Medicine

    Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

Ques: What is Sompraz D 40 Capsule Sr?

Ans: This medicine is a combination of Domperidone and Esomeprazole. These drugs are a part of the dopamine antagonists group of drugs and PPI, respectively and prevent the tendency of vomiting and nausea in people suffering from gastrointestinal problems and also those who take certain medicines for Parkinson’s disease. It consists of Domperidone which is an antiemetic agent and is used to treat nausea and vomiting.

Ques: What is Sompraz D 40 Capsule Sr used for?

Ans: It is used for Gastroesophageal reflux diseases, Treatment for symptoms correlated with idiopathic or diabetic gastroparesis, Peptic Ulcer and Gastric Ulcer, Helicobacter pylori infection, Gastric lesions, Treatment for intractable nausea,vomiting, stomach ulcer and other conditions.

Ques: What are the side effects of Sompraz D 40 Capsule Sr?

Ans: The subsequent side effects may be caused by the constituting elements of the Sompraz D 40. These effects may arise but are not always existing. These include
  • Headache
  • Diarrhea
  • Rash
  • Stomach pain

Ques: Is Sompraz D 40 Capsule Sr an over the counter drug?

Ans: It is not an over the counter drug and can be availed by you only after a certified doctor’s prescription. One should inform the doctor or the pharmacist from whom the medicine is being taken about any other medicine you just ate or are on because of the presence of domperidone and its work can be affected by other medicines.

Ques: Is it safe to use Sompraz D 40 Capsule Sr during pregnancy?

Ans: No, it is not safe to use it during pregnancy as it may lead to adverse effects on foetus.

Ques: Is it safe to use Sompraz D 40 Capsule Sr for breastfeeding mothers?

Ans: No, it is not safe to use it for breastfeeding mothers.

Ques: Is Sompraz D 40 Capsule Sr safe for allergic patient?

Ans: No, Sompraz d 40 is not adequate for the patients having any history of allergies.

Ques: What are the instructions for storage and disposal of Sompraz D 40 Capsule Sr?

Ans: It should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. It is important to dispose the expired and unused medications correctly to avoid adverse effects.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Pharmacology
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Sompraz D 40 Capsule Sr
What are the uses of Sompraz D 40 Capsule Sr
What are the contraindications of Sompraz D 40 Capsule Sr ?
What are the side effects of Sompraz D 40 Capsule Sr ?
Key highlights of Sompraz D 40 Capsule Sr
What are the substitutes for Sompraz D 40 Capsule Sr ?
What are the dosage instructions?
How does this medication work?
What are the interactions of Sompraz D 40 Capsule Sr ?
FAQs about Sompraz D 40 Capsule Sr