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Progeston 50 MG Injection

Manufacturer: Macmillon Pharmaceuticals
Medicine composition: Norethisterone
Prescription vs.OTC: Prescription by Doctor required

Norethisterone helps control excessive vaginal bleeding during menstruation. The drug is also effective in treating hormonal imbalance. Norethisterone aids in preventing unwanted pregnancies. The drug inhibits ovulation and transforms the lining of the uterus to ensure that eggs do not attach to it.

The medicine is known to produce certain side effects, such as weight gain, irregular menstrual bleeding, acne, dizziness, hirsutism and nausea. Before you administer the drug, tell your doctor if you are pregnant. It is also important to let the physician know if you suffer from liver disease, ovarian cysts, porphyria, breast cancer, or systemic lupus. Report all other medications you are on at the time of Norethisterone administration.

If your doctor deems you fit to take Norethisterone, he/she will administer it during the first 5 days of your menstrual cycle. If the drug is administered as an injection, it is injected into the buttock region. Consult your physician immediately if you suffer from allergies to the medication of components within the medication.

The efficiency of the drug varies from one person to the next, depending on the condition affecting them and sex hormone levels in the body.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Obstetrician before using this medicine.

Noresthisterone is recommended if you suffer from certain diseases, such as endometrial cancer, amenorrhoea, abnormal uterine bleeding, breast cancer and premenstrual syndrome. Apart from this, the medicine is useful as a contraceptive tool.

You should avoid the drug if you have an allergic reaction to it.

This medicine is not recommended for use if the patient has certain health complications like liver disease.

Abnormal vaginal bleeding

This medicine is not recommended for use if you have abnormal vaginal bleeding.

Breast/Uterine cancer

This medicine is not recommended for use if you have or are suspected of having breast/uterine cancer, and blood vessel disorder.
In addition to its intended effect, Progeston 50 MG Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Irregular menstrual periods

Moderate Less Common

Enlargement of breasts

Moderate Less Common

Stomach discomfort and pain

Minor Common

Weight loss or weight gain

Minor Less Common

Loss of vision or blurred vision

Major Rare

Migraine like headaches

Moderate Common

Difficulty in swallowing

Major Rare

Chest pain and discomfort

Moderate Less Common

Presence of blood in cough

Moderate Less Common

How long is the duration of effect?

The duration of Norethisterone’s effect varies from one person to the next, based on the intent of usage. Furthermore, the dosage administered also plays a vital role in determining the effect duration.

What is the onset of action?

The level of sex hormones in the body determines the time it takes for the medicine to show its intended effect. Additionally, your dosage is also an important factor for determining the onset of action.

Are there any pregnancy warnings?

The medicine should not be used if you are pregnant or are planning to conceive soon. Consult your physician if you think you might be pregnant while using the medicine.

Is it habit forming?

The medicine does not have any habit forming tendencies. However, you should stick to the dosage recommendation from your doctor to prevent any unforeseen complications of the medicine.

Are there any breast-feeding warnings?

The medicine is not recommended to breastfeeding women, as it can harm your child. Before starting the course of the drug, you should stop breastfeeding to protect your baby from unforeseen threats from the medicine.

Is It safe with alcohol?

The exact interaction of norethisterone with alcohol remains unclear. Therefore, consult your doctor to understand whether it is safe to consume alcohol along with the medication.

Is it safe to drive while on this medicine?

If you experience side effects such as, drowsiness or intense headaches from the medication, you should avoid driving. However, if there are no side effects, you can safely operate heavy machinery and drive after the medicine is administered.

Does this affect kidney function?

If you suffer from kidney disorders, let the doctor know. He/she will perform tests to determine whether the medication is safe for you under such circumstances.

Does this affect liver function?

While the medicine does not affect liver functionality, you should report to the doctor of pre-existing liver ailments. He/she will conduct tests and determine whether norethisterone is safe for your consumption.

Are there any missed dose instructions?

In case of a missed dose, take the dose as soon as you remember. However, if it is already time for your next dose, you can skip the missed dose. Use additional forms of contraceptive to avoid accidental pregnancies from missed doses of the drug.

Are there any overdose instructions?

Contact your doctor or visit your nearest clinic in case of an overdose. Symptoms such as vaginal bleeding, vomiting and nausea are common in case of overdose on norethisterone.


United States


Progeston 50 MG Injection works by inhibiting the secretion of gonadotropins from the pituitary gland and preventing the maturation of follicles and the process of ovulation.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Hepatic neoplasms


The drug interferes with the proper functioning of the body, if you suffer from certain diseases, such as depression, retinal thrombosis, fluid retention, hepatic neoplasms, and oedema. In such cases, an alternative to the drug should be used.

Interaction with Alcohol


Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Lab Test

Thyroid function test

Report the use of this medicine if a thyroid function test is advised. This medicine may interfere with the test results.

Interaction with Food


Information not available.

Interaction with Medicine



If you are taking norethisterone, make sure you are not on certain other drugs, such as phenytoin, divalproex, clarithromycin, phenobarbitol, aminophylline, Tranexamic acid, and Carbamazepine.

Ques: What is Progeston 50 MG Injection?

Ans: Norethisterone is a medication which has Norethindrone as an active ingredients present in it. This medicine performs its action by obstructing the release of pain and fever chemical messengers. Norethisterone is also used to avoid nasal congestion and common cold symptoms. Norethisterone is used to treat conditions such as Allergic reactions and vomiting.

Ques: What are the uses of Progeston 50 MG Injection?

Ans: Norethisterone is used for the treatment and prevention from conditions and symptoms of diseases like Endometrial cancer and abnormal uterine bleeding. Besides these, it can also be used to treat conditions like Breast cancer, Amenorrhoea and premenstrual syndrome. The patient should inform the doctor about any ongoing medications and treatment before using Norethisterone to avoid undesirable effects.

Ques: What are the Side Effects of Progeston 50 MG Injection?

Ans: This is a list of possible side-effects which may occur due to the constituting ingredients of Norethisterone. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include irregular menstrual periods, acneiform eruptions, eye bulging and migraine attacks. Apart from these, using Norethisterone may further lead to breathing difficulty, facial hair growth, dizziness, fainting and trouble sleeping. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

Ques: What are the instructions for storage and disposal Progeston 50 MG Injection?

Ans: Norethisterone should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of Norethisterone. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.
What are you using Progeston 50 MG Injection for?
Breast Cancer
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Hi. Doctor mujhe estogen and progeston mix injection lagaya hai lekin mujhe abhi bhi period start nahi hua and dubloc tablet subah sham batai hai khane ko urine pregnancy test kar chuke hai wo negative hai.

Gynaecologist, Kota
Hi. Doctor mujhe estogen and progeston mix injection lagaya hai lekin mujhe abhi bhi period start nahi hua and dubloc...
You will achieve menses 3-7 days (max 10 days) after last dose of dubloc. You can wait max for 10 days. If menses not achieved than consult doc.

Hi. Mujhe pcod ki probLem aaye hai .ek small cyst btaya hai ovary me. Uske bad mere doctor ne progeston ki tablet suru ki meri date k 16th day se. Kya Mujhe pcod ki ye bdi problem hai .isme conceive kr paungi main.

Unani Specialist, Kanchipuram
Mujhe pcod ki probLem aaye hai .ek small cyst btaya hai ovary me. Uske bad mere doctor ne progeston ki tablet sur...
Namaste Madam aap kitne din se dava chalu kiye hain batayiye agar aap abhi shuru kiye hain to aap chand mahine wait Karna padega kyon ke Dawa ka 2se 3 mah tak aap continue Karen agar aap ka Ilaj 3 mah hogaye hain to aap aapke Doctor se consult kar...

Why norethisterone and ethinylestradiol tablets should be used for a unmarried girl.

MS - Obstetrics and Gynaecology
Gynaecologist, Delhi
Why norethisterone and ethinylestradiol tablets should be used for a unmarried girl.
Norethisterone and ethinyl oestradiol combination pills are contraceptive pills, but they are also used in patients who have irregular periods or have excessive bleeding. It's use regularizes periods and in patients who have excessive bleeding it'...
2 people found this helpful

After completing norethisterone medicine. I was on periods next after the day. So am I be pregnant.

MD - Obstetrtics & Gynaecology, FMAS, DMAS, Fellowship in Assisted Reproductive technology, MBBS Bachelor of Medicine and Bachelor of Surgery
Gynaecologist, Noida
Hello, If menses have resumed, then pregnancy is unlikely but to confirm get a home urine pregnancy test done.

Can my girlfriend get pregnant with unprotected sex while taking Norethisterone tablets.

MD - Obstetrtics & Gynaecology
Gynaecologist, Thane
Can my girlfriend get pregnant with unprotected sex while taking Norethisterone tablets.
Dear lybrate-user, norethisterone is not a contraceptive pill. She can get pregnant on those medications. She should be taking oral contraceptive pills ie. Pregnancy avoiding pills.

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Table of Content
About Progeston 50 MG Injection
When is Progeston 50 MG Injection prescribed?
What are the contraindications of Progeston 50 MG Injection ?
What are the side effects of Progeston 50 MG Injection ?
Key highlights of Progeston 50 MG Injection
What are the dosage instructions?
Where is the Progeston 50 MG Injection approved?
How does medicine works?
What are the interactions for Progeston 50 MG Injection ?
Progeston 50 MG Injection Frequently Asked Questions (FAQs):