Progesterone

Progesterone is primarily used as intrauterine contraception in women who have had at least 1 child, are in a stable, mutually monogamous relationship, and have no history of the pelvic inflammatory disease; amenorrhea; functional uterine bleeding.

This medicine is also prescribed as replacement therapy. It is available as an intravaginal gel as part of assisted reproductive technology for infertile women with progesterone deficiency. Also it is used in secondary amenorrhea (8% gel is used in those who fail to respond to 4%).

Progesterone (active ingredient) is a synthetic version of the female hormone. This hormone is vital for the regulation of menstruation and ovulation. The medicine is primarily used to induce periods, specifically when it occurs due to a lack of hormone secretion.

It is also used to treat abnormal uterine bleeding and symptoms of premenstrual syndrome (PMS). Use of this medication could cause harm to the unborn baby if you do not let your doctor know that you are pregnant. The route of administration of this medicine is either intra-vaginal or intrauterine. Take this medication as per the prescription of the doctor.

This drug can be used in below-mentioned conditions

• Hormone Replacement Therapy (Hrt)

• Premenstrual Syndrome

• Absence Of Menstrual Periods

• Contraception

• Hypersensitivity

• Pregnancy

• Thrombophlebitis

• Vaginal Bleeding

• Liver Dysfunction

This drug can cause below-mentioned side effects

• Edema (Swelling)

• Bleeding

• Increased Menstrual Flow

• Amenorrhea

• Anorexia

• Weakness

• Embolism

• Central Nervous System Depression

• Fever

• Insomnia

• Melasma

• Breast Tenderness

• Unexpected Weight Gain Or Loss

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  This drug is unsafe to use during pregnancy.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  There is no interaction between driving and consuming this drug. So dose alteration is not needed.

• Does this affect kidney function?

  There is no data available. Please consult a doctor before consuming the drug.

• Does this affect liver function?

  There is no data available. Please consult a doctor before consuming the drug.

• How long is the duration of effect?

  The duration of effect of this medication is about 24 hours.

• What is the onset of action?

  The onset of action of this medication is 1.5 hours to 2.3 hours.

• Is it habit forming?

  No habit forming tendencies found.

• Are there any overdose instructions?

  In case of overdose, consult your doctor.

• Are there any missed dose instructions?

  The missed dose of this medicine should be taken as soon as you remember it. The missed dose, however, should be skipped if it is near the time of the next dose.

Below is the list of medicines, which contains Progesterone as ingredient

• Gynarone 200Mg Tablet Sr

  Themis Medicare Ltd

• Gestofert 300Mg Tablet Sr

  MMC Healthcare Ltd

• Ongest 300Mg Tablet

  Signova Pharma Pvt Ltd

• Susten 100 MG Injection

  Sun Pharma Laboratories Ltd

• Pregcert Lmf 500 Mcg/200 Mg Capsule

  Koye Pharmaceuticals Pvt ltd

• Mogest 300Mg Tablet Sr

  Maxamus International

• Gregest 200Mg Capsule

  Greyland Pharma Pvt Ltd

• Gestofit 400Mg Tablet Sr

  Alembic Pharmaceuticals Ltd

• Mini-Luton Vaginal Spray

  Shield Health Care Pvt Ltd

• Posito 100Mg Tablet

  Eris Life Sciences Pvt Ltd

This medication binds to the progesterone and estrogen receptors. The target cells are mammary gland, female reproductive tract, the pituitary and hypothalamus. When the binding takes place the release of GnRH is slowed and the luteinizing hormone rush.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Lab Test

  Inform your doctor if you are taking this medication before any pathological test. as this medicine may affect the result of tests like Thyroid function, metyrapone, liver function, coagulation tests, endocrine function tests.

• Interaction with Medicine

  This medication interacts with-
  • CYP3A3/4 enzyme: substrate or inducer
  • Increase effect: Ketoconazole may increase the bioavailability of progesterone. Progesterone may increase concentrations of estrogenic compounds during concurrent therapy with conjugated estrogens.
  • Other medications: Immunosuppressants, Antisteroidal drugs, Anticoagulants, Diazepam, Tizanidine, and Terbinafine.

• Interaction with Food

  No information available

• Interaction with Disease

  This medication interacts with the following diseases which include Coronary artery disease (CAD) and Gall bladder disease. Use with caution in patients with impaired liver function, depression, diabetes, and epilepsy. Use of any progestin during the first 4 months of pregnancy is not recommended. Monitor closely for loss of vision, proptosis, diplopia, migraine, and signs or symptoms of embolic disorders. Not a progestin of choice in the elderly for hormonal cycling.