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Overview

Prasugrel

Prescription vs OTC : Prescription by Doctor required

About Prasugrel

Prasugrel is used in the treatment of various heart and blood vessel problems that are life-threatening in nature. It belongs to a group of medications called antiplatelet.

It is used along with aspirin as it sometimes results in severe and fatal bleeding. The function of this medication is to prevent the accumulation of platelets that could ultimately lead to a stroke or a heart attack.

You have to take this medicine orally. The medicine is usually taken once every day with or without food. It is recommended to take this medication at the same time every day. This medicine should be taken as per doctor's prescription. Do not take multiple dosages at once as it can have harmful effects on the body.

This medicine should not be stopped abruptly as it leads to the blood clot formation which results in a heart attack. You need to inform your doctor about any Vitamin pills that you may be taking. You can follow your normal diet unless your doctor specifically asks you to alter it.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the uses of Prasugrel

    • Acute Coronary Syndrome

      This is used in the treatment of acute coronary syndrome which is a condition that blocks the blood flow to the heart muscles.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the contraindications of Prasugrel ?

    • Bleeding Disorders

      Not recommended in patients with any bleeding disorder like the peptic ulcer or brain injury.

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the side effects of Prasugrel ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    Key highlights of Prasugrel

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 24 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 30 minutes.

    • Are there any pregnancy warnings?

      This medicine is recommended in pregnant women only if necessary. The benefits and risks should be discussed with the doctor before receiving this medicine.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      The excretion of this medicine in breast milk is unknown. It is used in pregnant women only if necessary. The benefits and risks should be discussed with the doctor before taking this medicine.

    • Does this affect kidney function?

      Limited information is available in this reference.

    • Does this affect liver function?

      Dosage adjustment is not needed in cases of mild to moderate hepatic impairment patients, whereas this medication is contraindicated in patients with severe liver impairment.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    Where is the Prasugrel approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    Medicines containing Prasugrel

    Below is the list of medicines, which contains Prasugrel as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    How does this medication work?

    This medication belongs to Platelet aggregation inhibitors. It works by inhibiting the activation of platelets and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

      What are the interactions of Prasugrel ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Medicine

        Escitalopram

        These medications may increase the risk of bleeding if taken together. Inform the doctor if you are receiving any antidepressant medications. Seek immediate medical treatment if you have any symptoms of unusual bleeding, gastrointestinal bleeding, dizziness. An alternate class of medicine should be considered based on the clinical condition.

        Warfarin

        These medications may increase the risk of bleeding if taken together. Inform the doctor if you are receiving any medicines that prevent clot formation. Seek immediate medical treatment if you have any symptoms of unusual bleeding, gastrointestinal bleeding, dizziness. An alternate class of medicine should be considered based on the clinical condition.

        Nonsteroidal anti-inflammatory drugs

        These medications may increase the risk of bleeding if taken together. Inform the doctor if you are receiving any pain killers. Seek immediate medical treatment if you have any symptoms of unusual bleeding, gastrointestinal bleeding, dizziness. An alternate class of medicine should be considered based on the clinical condition.
      • Interaction with Disease

        Bleeding Disorders

        This medicine may increase the risk of bleeding, therefore not recommended in patients with the bleeding disorder. Inform the doctor if you have any gastrointestinal diseases or an injury. Close monitoring of platelets count is necessary.

      FAQs about Prasugrel

      • Ques : What is Prasugrel?

        Ans : This medication is used in the treatment of various heart and blood vessel problems that are life-threatening in nature.

      • Ques : How long do I need to use Prasugrel before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Prasugrel?

        Ans : This medication should be taken once in a day in the dosage as prescribed by the doctor.

      • Ques : Should I use Prasugrel empty stomach, before food or after food?

        Ans : This medication can be taken with or without food.

      • Ques : What are the instructions for the storage and disposal of Prasugrel?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Prasugrel- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 4 December 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/prasugrel

      • Prasugrel- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 4 December 2019]. Available from:

        https://www.drugbank.ca/drugs/DB06209

      • Efient 10 mg film-coated tablets- EMC [Internet] medicines.org.uk. 2018 [Cited 4 December 2019]. Available from:

        https://www.medicines.org.uk/emc/product/6466/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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