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Paracetamol 500 MG Tablet

Manufacturer :  Cadila Pharmaceuticals Ltd
Medicine Composition :  Paracetamol
Prescription vs OTC : Prescription by Doctor not required

About Paracetamol 500 MG Tablet

Paracetamol 500 MG Tablet is used a pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis and toothache, etc.

The active ingredient falls under the class of analgesics, belonging to the category of NSAID. This medication also reduces pain in the body caused due to fever.

You should not consume this tablet if:

  • You are allergic to this medicine.
  • You are suffering from a serious liver disorder.
  • You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

If people experience allergic reactions to this pill, then that means that they should not take it. As Paracetamol 500 MG Tablet is an OTC tablet, up to 500mg dose, many people tend to use it randomly, and this is not good. It is always better to speak to your doctor before taking any medicine.

There are several drugs that may interact with Paracetamol. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over the counter drugs, and herbal products.

For adults Paracetamol the general dose for fever and pain is 325-650 mg tablets once in every 4 to 6 hours or 1000mg tablets once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

For treating Paracetamol 500 MG Tablet toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.

Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.

Take exactly as directed (do not increase dose or frequency); most adverse effects are related to excessive use. Take with food or milk. While using this medication, avoid alcohol and other prescription or OTC medications that contain acetaminophen or Paracetamol 500 MG Tablet.

    What are the uses of Paracetamol 500 MG Tablet

    • Fever

    • Headache

    • Muscle Pain

    • Menstrual Cramps

    • Post Immunization Pyrexia

    • Arthritis

    What are the contraindications of Paracetamol 500 MG Tablet ?

    What are the side effects of Paracetamol 500 MG Tablet ?

    • Nausea Or Vomiting

    • Allergic Skin Reaction

    • Gastric / Mouth Ulcer

    • Fatigue

    • Anemia

    • Stevens-Johnson Syndrome (Sjs)

    Key highlights of Paracetamol 500 MG Tablet

    • How long is the duration of effect?

      The effect lasts for an average of 4-6 hours.

    • What is the onset of action?

      The effect of this drug can be observed within an hour of administration.

    • Are there any pregnancy warnings?

      It should be used only when necessary after consulting a doctor in pregnant women.

    • Is it habit forming?

      There are no habit forming tendencies reported with this pill.

    • Are there any breast-feeding warnings?

      This medicine is not safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine.

    • Is It safe with alcohol?

      Excessive intake of alcohol may increase the risk of acetaminophen-induced hepatotoxicity; avoid or limit alcohol intake.

    • Is it safe to drive while on this medicine?

      Yes, you can drive after taking this pill.

    • Does this affect kidney function?

      Dose adjustment is needed in case of renal impairment. Dosing interval in renal impairment:

      • Clcr 10-50 mL/minute: Administer every 6 hours.
      • Clcr <10 mL/minute: Administer every 8 hours (metabolites accumulate)
      • Hemodialysis: Moderately dialyzable (20% to 50%).
      Consult your doctor before taking this medication.

    • Does this affect liver function?

      Patients who have impaired liver function should not take this pill as it can lead to more liver problems, including liver failure. Appears to be well tolerated in cirrhosis; serum levels may need monitoring with long-term use.

    What are the substitutes for Paracetamol 500 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Paracetamol 500 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose, you should take one as soon as you remember that you’ve missed the dose.

    • Are there any overdose instructions?

      If you have overdosed on the pill, you must consult your doctor immediately. Certain signs of overdose include confusion, drowsiness and lightheadedness.

    How does this medication work?

    The drug is a pain relief medication that is administered orally. It selectively inhibits enzyme function in the brain which allows it to treat pain and fever. The medicine activates certain receptors in the brain that inhibit pain signals.

      What are the interactions of Paracetamol 500 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

      • Interaction with Alcohol

        You should avoid consuming alcohol while taking this medicine. Symptoms like fever, chills, rashes, joint pain and swelling, excessive weakness, nausea should be immediately reported to the doctor.
      • Interaction with Lab Test

        5-HIAA Urine Test

        You may get a false-positive result for this test if you take Paracetamol.
      • Interaction with Medicine

        One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives if administered concomitantly. Also, Barbiturates, carbamazepine, hydantoins, sulfinpyrazone can increase the hepatotoxic potential of acetaminophen; chronic ethanol abuse increases the risk for acetaminophen toxicity; effect of warfarin may be enhanced.

      • Interaction with Disease

        It can have negative interactions with certain diseases. These include impaired kidney function, and impaired liver function.

      • Interaction with Food

        This medication may slightly delay absorption of extended-release preparations; rate of absorption may be decreased when given with food high in carbohydrates.

      FAQs about Paracetamol 500 MG Tablet

      • Ques : What is Paracetamol 500 MG Tablet?

        Ans : This is a medication that performs its action by obstructing the release of pain and fever chemical messengers.

      • Ques : What are the uses of Paracetamol 500 MG Tablet?

        Ans : This medicine is used for the treatment and prevention of conditions and symptoms of diseases like Post immunization pyrexia, menstrual cramps and fever.

      • Ques : What are the Side Effects of Paracetamol 500 MG Tablet?

        Ans : Allergic reaction, gastric ulcers, fatigue, anemia, nausea and vomiting are possible side effects.

      • Ques : What are the instructions for storage and disposal Paracetamol 500 MG Tablet?

        Ans : This medicine should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      • Ques : Should I use Paracetamol 500 MG Tablet empty stomach, before food or after food?

        Ans : If you take this medication with the food, the reactions that took place in the body carry-outs in a much effective manner.

      • Ques : How long do I need to use Paracetamol 500 MG Tablet before I see improvement in my conditions?

        Ans : This medication should be consumed, until the complete eradication of the disease. It is advised to use, till the time directed by your doctor.

      • Ques : Is there any food or drink I need to avoid while taking Paracetamol 500 MG Tablet?

        Ans : You can follow your normal diet under the usage of this medication.

      • Ques : Will Paracetamol 500 MG Tablet be more effective if taken in more than the recommended dose?

        Ans : There is no need to take this medication more than its recommended doses.

      • Ques : Can I take other medications along with Paracetamol 500 MG Tablet?

        Ans : Do not use any OTC for cough, cold, allergy, or pain medication without consulting your doctor or pharmacist. Paracetamol 500 MG Tablet contains many combination of medicines. If you use certain products together you may accidentally use too much of Paracetamol 500 MG Tablet.

      • Ques : Can I take Paracetamol 500 MG Tablet with antibiotics?

        Ans : There are hundreds of antibiotics used to treat infections, so once you receive your prescription, ask your doctor or pharmacist if you can also take this medication at the same time that you take the antibiotic.

      • Ques : Is Paracetamol 500 MG Tablet an NSAID drug?

        Ans : No, this medication is not classified as an NSAID (nonsteroidal anti-inflammatory drug). It is classified as a miscellaneous analgesic for mild to moderate pain and fever.


      • Anadin Paracetamol Tablets- EMC [Internet]. 2016 [Cited 24 April 2019]. Available from:

      • Acetaminophen- Drug Information Portal [Internet]. 2019 [Cited 24 April 2019]. Available from:

      • Crocin: Uses, Side Effects, Precautions, Dosage- Drugs Bank [Internet]. 2018 [Cited 24 April 2019]. Available from:

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician

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