Paracetamol 500 MG Tablet

Paracetamol 500 MG Tablet is used a pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis and toothache, etc.

The active ingredient falls under the class of analgesics, belonging to the category of NSAID. This medication also reduces pain in the body caused due to fever.

You should not consume this tablet if:

• You are allergic to this medicine.
• You are suffering from a serious liver disorder.
• You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

If people experience allergic reactions to this pill, then that means that they should not take it. As Paracetamol 500 MG Tablet is an OTC tablet, up to 500mg dose, many people tend to use it randomly, and this is not good. It is always better to speak to your doctor before taking any medicine.

There are several drugs that may interact with Paracetamol. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over the counter drugs, and herbal products.

For adults Paracetamol the general dose for fever and pain is 325-650 mg tablets once in every 4 to 6 hours or 1000mg tablets once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

For treating Paracetamol 500 MG Tablet toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.

Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.

Take exactly as directed (do not increase dose or frequency); most adverse effects are related to excessive use. Take with food or milk. While using this medication, avoid alcohol and other prescription or OTC medications that contain acetaminophen or Paracetamol 500 MG Tablet.

Paracetamol is helpful in treating the below provided problems:

• Fever

• Headache

• Muscle Pain

• Menstrual Cramps

• Post Immunization Pyrexia

• Arthritis

• Allergy

• Analgesic Nephropathy (Kidney Disease)

• Liver Disease

Side effects of Paracetamol are as follows:

• Nausea Or Vomiting

• Allergic Skin Reaction

• Gastric / Mouth Ulcer

• Fatigue

• Anemia

• Stevens-Johnson Syndrome (Sjs)

• How long is the duration of effect?

  The effect lasts for an average of 4-6 hours.

• What is the onset of action?

  The effect of this drug can be observed within an hour of administration.

• Are there any pregnancy warnings?

  It should be used only when necessary after consulting a doctor in pregnant women.

• Is it habit forming?

  There are no habit forming tendencies reported with this pill.

• Are there any breast-feeding warnings?

  This medicine is not safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine.

• Is It safe with alcohol?

  Excessive intake of alcohol may increase the risk of acetaminophen-induced hepatotoxicity; avoid or limit alcohol intake.

• Is it safe to drive while on this medicine?

  Yes, you can drive after taking this pill.

• Does this affect kidney function?

  Dose adjustment is needed in case of renal impairment. Dosing interval in renal impairment:
  • Clcr 10-50 mL/minute: Administer every 6 hours.
  • Clcr <10 mL/minute: Administer every 8 hours (metabolites accumulate)
  • Hemodialysis: Moderately dialyzable (20% to 50%).
  Consult your doctor before taking this medication.

• Does this affect liver function?

  Patients who have impaired liver function should not take this pill as it can lead to more liver problems, including liver failure. Appears to be well tolerated in cirrhosis; serum levels may need monitoring with long-term use.

Below is the list of medicines, which have the same composition, strength and form as Paracetamol 500 MG Tablet , and hence can be used as its substitute.

• Parawok 500 MG Tablet

  Wockhardt Ltd

• Merimol 500 MG Tablet

  Wockhardt Ltd

• Dolomol 500 MG Tablet

  Micro Labs Ltd

• Amol 500 MG Tablet

  Unichem Laboratories Ltd

• Parafast 500 MG Tablet

  Cipla Ltd

• Are there any missed dose instructions?

  If you miss a dose, you should take one as soon as you remember that you’ve missed the dose.

• Are there any overdose instructions?

  If you have overdosed on the pill, you must consult your doctor immediately. Certain signs of overdose include confusion, drowsiness and lightheadedness.

The drug is a pain relief medication that is administered orally. It selectively inhibits enzyme function in the brain which allows it to treat pain and fever. The medicine activates certain receptors in the brain that inhibit pain signals.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Alcohol

  You should avoid consuming alcohol while taking this medicine. Symptoms like fever, chills, rashes, joint pain and swelling, excessive weakness, nausea should be immediately reported to the doctor.

• Interaction with Lab Test

  5-HIAA Urine Test

  You may get a false-positive result for this test if you take Paracetamol.

• Interaction with Medicine

  One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives if administered concomitantly. Also, Barbiturates, carbamazepine, hydantoins, sulfinpyrazone can increase the hepatotoxic potential of acetaminophen; chronic ethanol abuse increases the risk for acetaminophen toxicity; effect of warfarin may be enhanced.

• Interaction with Disease

  It can have negative interactions with certain diseases. These include impaired kidney function, and impaired liver function.

• Interaction with Food

  This medication may slightly delay absorption of extended-release preparations; rate of absorption may be decreased when given with food high in carbohydrates.