Nioclean Ad Gel

Manufacturer: KLM Laboratories Pvt Ltd
Medicine composition: Adapalene, Clindamycin
Prescription vs OTC: Prescription by Doctor not required
Last Updated: March 22, 2022

Nioclean Ad Gel is a combination of two drugs, Adapalene and Clindamycin, primarily used to treat acne vulgaris. These drugs belong to a class of drugs called retinoids and lincosamide (an antibacterial) respectively.

This medicament works by decreasing the formation of blackheads and helps to renew skin faster. It also kills the microorganism responsible for causing acne. It also helps to heal pimples, whiteheads and blackheads on the skin by reducing skin inflammation and swelling.

If you are allergic to any of the ingredients of Nioclean Ad Gel, it is not be used. If you suffer from sunburn or eczema, its usage is not advised as well. Alert your doctor if you are allergic to Vitamin A drugs and other retinoid drugs such as isotretinoin.

The medicament is only meant for external use, and should not be applied to abrasions, cuts or sunburned skin. Avoid contact with eyes as it may cause redness and irritation. Nioclean Ad Gel may cause your skin to become sunburned easily, so it is advisable to limit your time in the sun.

This medicament may cause some burning and stinging earlier on. Peeling, redness, scaling and dryness of skin may be seen too. Find medical attention immediately if you experience rashes, difficulty in breathing and swelling of face and lips.

Following conditions can be restored by utilising this gel

  • Acne

Side effects of this gel are listed below

  • Skin Irritation

  • Burning Or Tingling Sensation Of Skin

  • Redness Of Skin

  • Peeling And Blistering Of Skin

  • Patchy Appearance Of Skin

  • Photosensitivity Of Skin

  • Is It safe with alcohol?

    No interaction found
  • Are there any pregnancy warnings?

    This medicine should be avoided by pregnant women unless suggested by the doctor. The effect of this medicine on fetus is not clearly established and hence, doctor consultation is recommended before consumption.
  • Are there any breast-feeding warnings?

    This medicine is probably unsafe to use during breastfeeding. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    There is no data available. Please consult doctor before consuming the drug.
  • Does this affect kidney function?

    There is no data available. Please consult doctor before consuming the drug.
  • Does this affect liver function?

    There is no data available. Please consult doctor before consuming the drug.

This medication is a combination of Adapalene and Clindamycin, thus it works following a dual mechanism. Firstly, it works by mechanistically combining with certain retinoic acid nuclear receptors as well as retinoid X receptors. It does not combine with cytosolic receptor protein, however. The exact working nature of this medicine is not known. Secondly, it works by binding to the 50S subunit of the bacterial ribosome thus inhibits the protein synthesis in the bacteria and stops the growth of the bacteria. Thus it inhibits the bacterial growth responsible for causing acne.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Medicine


    Do not use this gel in combination with salicylic Acid, neuromuscular blockers and isotretinoin.
  • Interaction with Disease


    Patients suffering from Eczema, Sunburn and Gastrointestinal Diseases should exercise caution while using this medication.

Ques: What is Nioclean Ad Gel?

Ans: This medication is a combination of Adapalene and Clindamycin. These two drugs belong to the class named retinoid and lincosamide respectively. This medicament is primarily prescribed to treat acne (Nodulocystic or Resistant acne).

Ques: What is the use of Nioclean Ad Gel?

Ans: This Gel is used for the treatment and prevention from conditions and symptoms of diseases like severe acne on face, pimples, spots, and keratosis pilaris.

Ques: What are the side effects of Nioclean Ad Gel?

Ans: Common side effects include burning, drying, and skin irritation. Apart from these, using this medicine may further lead to erythema, dryness, scaling, and diarrhea.

Ques: What are the instructions for storage and disposal of Nioclean Ad Gel?

Ans: This medicament should be stored at cool dark place, away from heat and direct light. Keep it away from the reach of children and pets.

Ques: How long do I need to use Nioclean Ad Gel before I see improvement in my condition?

Ans: In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 month, before noticing an improvement in the condition.

Ques: At what frequency do I need to use Nioclean Ad Gel?

Ans: This medication is generally used once a day, as the time interval to which this medication has an impact, is around 24 hours, but it is not the standard frequency, for using this medication.

Ques: Should I use Nioclean Ad Gel empty stomach, before food or after food?

Ans: This medication is commonly used by applying it to the affected area. As this medication is for external use, the action of salts involved in this medication does not depend on whether taking it pre-meal or post-meal.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MD-Pharmacology, MBBS
Table of Content
About Nioclean Ad Gel
What are the uses of Nioclean Ad Gel
What are the contraindications of Nioclean Ad Gel ?
What are the side effects of Nioclean Ad Gel ?
Key highlights of Nioclean Ad Gel
How does this medication work?
What are the interactions of Nioclean Ad Gel ?
FAQs about Nioclean Ad Gel