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Overview

Megamentin -625 Tablet

Manufacturer :  Intas Pharmaceuticals Ltd
Medicine Composition :  Amoxycillin, Clavulanic Acid
Prescription vs OTC : Prescription by Doctor not required

About Megamentin -625 Tablet

Megamentin -625 Tablet is prescribed for the treatment of otitis media, sinusitis, and infections caused by susceptible organisms involving the lower respiratory tract, skin and skin structure, and urinary tract. This is a combination medication that has Amoxycillin and Clavulanic Acid as active ingredients. Its spectrum is the same as amoxicillin with additional coverage of beta-lactamase.

The extended coverage Megamentin -625 Tablet is due to its combination, which makes it a useful alternative when amoxicillin resistance is present and patients cannot tolerate alternative treatments.

Megamentin -625 Tablet is an antibiotic belonging to the class of penicillin antibiotic that helps in the treatment of bacterial infections. The medicine works against the synthesis of the bacteria. It also treats conditions like gonorrhoea, tonsillitis, infection in the eye, middle ear or nose. It is important that you do not consume this tablet for cold, flu or other viral infections.

Symptoms of penicillin overdose include neuromuscular hypersensitivity (agitation, hallucinations, asterixis, encephalopathy, confusion, and seizures) and electrolyte imbalance with potassium or sodium salts, especially in renal failure.

Hemodialysis may be helpful to aid in the removal of the drug from the blood, otherwise most treatment is supportive or symptom directed.

Take entire prescription, even if you are feeling better. Take at equal intervals around-the-clock; may be taken with milk, juice, or food. You may experience nausea or vomiting (small frequent meals, frequent mouth care, sucking lozenges, or chewing gum may help).

If using oral contraceptives, use additional contraceptive measures; amoxicillin may reduce the effectiveness of your oral contraceptive. Report rash; unusual diarrhoea; vaginal itching, burning, or pain; unresolved vomiting or constipation; fever or chills; unusual bruising or bleeding; or if the condition being treated worsens or does not improve by the time prescription is completed.

    What are the uses of Megamentin -625 Tablet

    What are the contraindications of Megamentin -625 Tablet ?

    What are the side effects of Megamentin -625 Tablet ?

    Key highlights of Megamentin -625 Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average of 1.5 to 2 hours.

    • What is the onset of action?

      The effect of this medicine can be observed within 1-2 hours of administration.

    • Are there any pregnancy warnings?

      This medicine is not known to cause any harm to the fetus. But the evidence is inadequate and it should be used only when necessary after consulting a doctor.

    • Is it habit forming?

      No habit forming tendencies have been reported.

    • Are there any breast-feeding warnings?

      This medicine is safe to use during breastfeeding. Any incidence of rashes on skin or diarrhea in the infant should be reported. It is advised to consult a doctor before taking this medicine.

    • Is It safe with alcohol?

      Interaction of the drug with alcohol is unknown, but you should seek advice from your physician regarding mixing a dose of the drug with alcohol.

    • Is it safe to drive while on this medicine?

      Driving is safe, as long as you do not experience side effects, such as drowsiness. If you do feel sleepy after consuming the medicine, avoid driving or operating any heavy machinery.

    • Does this affect kidney function?

      If you suffer from kidney disorders, you should exercise extreme caution while using the drug. If severe kidney diseases affect you, you should avoid Megamentin -625 Tablet altogether, as it can lead to complications.

    • Does this affect liver function?

      Patients suffering from liver disease should try to avoid the medicine. However, if prescribed, the doctor may adjust the dosage to ensure that the drug do not adversely affect the organ. Furthermore, such patients should undergo tests to monitor liver functionality.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon as possible.

    • Are there any overdose instructions?

      One should contact the doctor immediately if an overdose is suspected.

    How does this medication work?

    This medication is a penicillin antibiotic and inhibits the transfer of a peptide group in the transpeptidation process. As a result, the bacterium is not able to build cell walls and killed. It also works as a beta-lactamase inhibitor by binding to beta-lactamase enzyme produced by bacterial cells, which in turn inhibits its enzymatic action and prevents beta-lactam antibiotics from being metabolised by the enzyme.

      What are the interactions of Megamentin -625 Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Even though interaction with alcohol has not been proven, you should consult your doctor if you are planning to consume alcoholic drinks during the course of the medication.
      • Interaction with Medicine

        Megamentin -625 Tablet can interact with certain medicines or supplements to cause severe side effects. You must discuss the medicines you currently are taking with the doctor so that he/she can prescribe your substitutes.
        • Doxycycline, methotrexate, warfarin, ethinylestradiol and live vaccines are some of the medicines that interact with this medication to cause adverse side effects.
        • Decreased effect: Efficacy of oral contraceptives may be reduced.
        • Increased effect: Disulfiram, probenecid may increase amoxicillin levels, increased effect of anticoagulants.
        • Increased toxicity: Allopurinol theoretically has an additive potential for amoxicillin rash.
      • Interaction with Food

        Generally antibiotics are taken after meals. Therefore, the drug does not interact adversely with your foods. However, consult the physician to get a clearer idea about how and when to take the medicine. May mix with milk, formula, or juice.
      • Interaction with Disease

        In patients with renal impairment, doses and/or frequency of administration should be modified in response to the degree of renal impairment; high percentage of patients with infectious mononucleosis have developed rash during therapy; a low incidence of cross-allergy with cephalosporins exists; incidence of diarrhea is higher than with amoxicillin alone. Hepatic dysfunction, although rare, is more common in elderly and/or males, and occurs more frequently with prolonged treatment.

      FAQs about Megamentin -625 Tablet

      • Ques : What is Megamentin 625 tablet?

        Ans : Megamentin tablet is a combination medicine used to treat a variety of bacterial infections. It contains Amoxicillin and Clavulanic Acid as active ingredients.

      • Ques : What are the uses of Megamentin 625 tablet?

        Ans : Megamentin tablet is used for the treatment of diseases like Otitis Media, Sinusitis, throat infection and lower respiratory tract infection.

      • Ques : What are the Side Effects of Megamentin 625 tablet?

        Ans : Possible side-effects include fever, joint pain, skin yellowing, easy bruising and bleeding, heavy menstrual bleeding, and tooth discoloration.

      • Ques : What are the instructions for storage and disposal Megamentin 625 tablet?

        Ans : Megamentin should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      • Ques : What are the contraindications to Megamentin -625 Tablet?

        Ans : The tablet should not be used if you have the following conditions such as hives, swelling of the face or throat, allergic reaction to an injection of foreign protein, skin rash, itching, etc.

      • Ques : Is Megamentin -625 Tablet safe to use when pregnant?

        Ans : This medication is not recommended for use in pregnant women unless absolutely necessary.

      • Ques : Will Megamentin -625 Tablet be more effective if taken in more than the recommended dose?

        Ans : No, taking higher than the recommended dose can lead to increased chances of side effects.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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