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Letoval Tablet

Manufacturer: Sun Pharmaceutical Industries Ltd
Medicine composition: Letrozole
Prescription vs.OTC: Prescription by Doctor not required

Letrozole is a drug sold under the trade name Femara for the treatment of breast cancer in post-menopausal women. Sometimes, excess estrogen in the body can stimulate cancerous cells to grow in the breasts. Letrozole is commonly used to treat estrogen-dependent tumours. It belongs to a group of drugs called aromatase inhibitors that prevents the conversion of androgen to estrogen in women. In menopausal women, the ovaries do not produce estrogen. Instead, the body fat, using a protein called aromatase, produce it. Letrozole inhibits the production of estrogen and thus prevents the growth of a tumour.

Letrozole also increases the thickness of the endometrium and improves follicular development in the ovaries. Letrozole can also induce ovulation in females if they are unable to do so naturally. Sometimes, this drug can be also prescribed to men with breast cancer. Letrozole is only prescribed if the biopsy shows oestrogen receptors within the cells.

Letrozole helps to reduce chances of the cancer returning to the same breast or metastasize. Letrozole is taken as a tablet, once a day for 5 days, with or without food.

  • Breast Cancer

    It is prescribed to women with estrogen-induced breast cancer. It is usually given after chemotherapy and radiotherapy. Sometimes, it is prescribed to reduce the size of the tumour before surgery. It may also be prescribed to reduce the growth of the cancerous cells if surgery is not an option for you. It can also be used to treat recurring tumours.

  • How long is the duration of effect?

    Since, Letrozole is an endocrine therapy, it needs to be taken for 5 years after the surgery to maintain its effect on the cancer.

  • What is the onset of action?

    The drug therapy requires a minimum of 3-4 months to show any effect on the tumour.

  • Are there any pregnancy warnings?

    Letrozole is used in post-menopausal women only. It is contraindicated in pregnant women.

  • Is it habit forming?

    It is not habit-forming.

  • Are there any breast-feeding warnings?

    This drug is incompatible with breastfeeding women. There is an increased risk of foetal malformation.

  • Is It safe with alcohol?

    It is unsafe to drink alcohol while undergoing this hormone therapy for increases chances of headaches and nausea.

  • Is it safe to drive while on this medicine?

    Drive with caution if you are suffering from any of the side-effects.

  • Does this affect kidney function?

    There has been no kidney impairment reported due to this hormone therapy.

  • Does this affect liver function?

    It increases the enzyme level in the liver and interferes with the normal functioning of the liver.

Below is the list of medicines, which have the same composition, strength and form as Letoval Tablet , and hence can be used as its substitute.

  • Are there any missed dose instructions?

    If you miss a dose, you do not need to take it the next day since the hormone level in your system will be high enough from the previous day.

  • Are there any overdose instructions?

    Contact emergency services immediately if you overdose. Overdosing will enhance the severity of the side-effects.

Letoval Tablet belongs to nonsteroidal aromatase inhibitors. It works by inhibiting the aromatase enzyme by competitively binding to the heme of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues. Thus inhibits the growth of cancer of the breast.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol


    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Interaction with Medicine


    Letrozole interacts with other estrogen-containing drugs like hormone replacement therapy (HRT) and other drugs like ethinylestradiol, tamoxifen, cholera vaccine and eluxadoline.

  • Interaction with Disease


    Letrozole is dangerous to be used in patients with existing liver disease. The drug increases the enzyme level in the liver.

  • Interaction with Food


    Information not available.

Ques: What is Letoval Tablet?

Ans: Letoval Tablet is a medication which has Letrozole as an active ingredient present in it. This is an anticancer medication that performs its action by decreasing the amount of estrogen and stopping the growth of breast cancer. Letoval Tablet is used to treat conditions such as Breast cancer. It is used to decrease the level of estrogen.

Ques: What are the uses of Letoval Tablet?

Ans: Letoval Tablet is a medication, which is used for the treatment and prevention from conditions such as Breast cancer. It decreases the level of estrogen in the body. The patient should inform the doctor about any ongoing medications and treatment before using Letoval Tablet to avoid undesirable effects.

Ques: What are the Side Effects of Letoval Tablet?

Ans: Letoval Tablet is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of Letoval Tablet which are Bone fractures, Chest pain, Dizziness, Headache, hair loss, Back pain, Hot flashes, Constipation, Anxiety, nervousness, Increased thirst and appetite. It is a list of possible side-effects which may occur due to the constituting ingredients of Letova Tablet.

Ques: What are the instructions for storage and disposal Letoval Tablet?

Ans: Letoval Tablet should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects. It is important to dispose expired and unused medications properly to avoid adverse effects.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Letoval Tablet
What are the uses of Letoval Tablet
What are the contraindications of Letoval Tablet ?
What are the side effects of Letoval Tablet ?
Key highlights of Letoval Tablet
What are the substitutes for Letoval Tablet ?
What are the dosage instructions?
How does this medication work?
What are the interactions of Letoval Tablet ?
FAQs about Letoval Tablet