Hyaluronidase is an enzyme solution that can be injected and helps in enhancing the natural degradation of hyaluronic acid. It being a spreading substance is combined with other medicines and injected under the skin to improvise their absorption by the body when the drug cannot be injected into the vein. It also improves the absorption of radioactive substances during subcutaneous urography.
The first dose of Hyaluronidase must be given after a skin test to check whether the person is allergic to it or not. It should not be directly applied in the eye or injected into infected skin or vein. It should not be used to catalyse the absorption of dopamine or alpha agonist medicines. The physician should be contacted if a dose is missed.
Hyaluronidase is available in the form of solution or powder for solution in strength(s) of 150 units/ml, 200 units/ml, 150 units, 1500 units and 6200 units. For proper dosage a physician or pharmacist should be consulted.
Side effects of Hyaluronidase include skin rashes and redness, itching, unusual weakness, difficulty in swallowing, dizziness, tightness in the chest, swelling of eyelids, lips, tongue or face, fast heartbeat, cough.
Is It safe with alcohol?Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?Hynidase 1500iu injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?Hynidase 1500iu injection is probably safe to use during breastfeeding. Please consult your doctor.
Is it safe to drive while on this medicine?There is no interaction between driving and consuming this drug. So dose alteration is not needed.
Does this affect kidney function?There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?There is no data available. Please consult doctor before consuming the drug.
Are there any missed dose instructions?If you miss a dose of Hyaluronidase, skip it and continue with your normal schedule. Do not double the dose.
Below is the list of medicines, which contains Hyaluronidase as ingredient
This medication behaves as an enzyme that acts as a diffusing substance. It hydrolyzes cellular cementing substance hyaluronic acid by splitting glucosaminide bonds, temporarily decreasing the viscosity and increasing the diffusion of injected fluids and helping their absorption.
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