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Hyaluronidase

Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 14, 2018

Hyaluronidase is an enzyme solution that can be injected and helps in enhancing the natural degradation of hyaluronic acid. It being a spreading substance is combined with other medicines and injected under the skin to improvise their absorption by the body when the drug cannot be injected into the vein. It also improves the absorption of radioactive substances during subcutaneous urography.

The first dose of Hyaluronidase must be given after a skin test to check whether the person is allergic to it or not. It should not be directly applied in the eye or injected into infected skin or vein. It should not be used to catalyse the absorption of dopamine or alpha agonist medicines. The physician should be contacted if a dose is missed.

Hyaluronidase is available in the form of solution or powder for solution in strength(s) of 150 units/ml, 200 units/ml, 150 units, 1500 units and 6200 units. For proper dosage a physician or pharmacist should be consulted.

Side effects of Hyaluronidase include skin rashes and redness, itching, unusual weakness, difficulty in swallowing, dizziness, tightness in the chest, swelling of eyelids, lips, tongue or face, fast heartbeat, cough.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Cosmetic/Plastic Surgeon before using this medicine.

In addition to its intended effect, Hyaluronidase may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Acute urticaria

Hormone imbalance

Slow growth in children and teenagers

Angioedema (swelling of deeper layers of skin)

Injection site reaction

Edema.

Is It safe with alcohol?

Interaction with alcohol is unknown. Please consult your doctor.

Are there any pregnancy warnings?

Hynidase 1500iu injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Are there any breast-feeding warnings?

Hynidase 1500iu injection is probably safe to use during breastfeeding. Please consult your doctor.

Is it safe to drive while on this medicine?

There is no interaction between driving and consuming this drug. So dose alteration is not needed.

Does this affect kidney function?

There is no data available. Please consult doctor before consuming the drug.

Does this affect liver function?

There is no data available. Please consult doctor before consuming the drug.

Are there any missed dose instructions?

If you miss a dose of Hyaluronidase, skip it and continue with your normal schedule. Do not double the dose.
Below is the list of medicines, which contains Hyaluronidase as ingredient
Shreya Life Sciences Pvt Ltd
Sunways India Pvt Ltd
Cadila Pharmaceuticals Ltd
Ajanta Pharma Ltd
Entod Pharmaceuticals Ltd
Hyaluronidase is an enzyme that acts as a diffusing substance. It hydrolyzes cellular cementing substance hyaluronic acid by splitting glucosaminidic bonds, temporarily decreasing the viscosity and increasing diffusion of injected fluids and helping their absorption.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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About Hyaluronidase
What are the side effects of Hyaluronidase ?
Key highlights of Hyaluronidase
What are the dosage instructions?
Medicines containing Hyaluronidase
How does medicine works?