This medication a part of the dopamine antagonists and NSAID group of drugs used to treat migraine. This medicine prevents the signal of pain to reach the brain, thus reduces pain. Migraine pain causes nausea and vomiting stimulating the receptors in the brain responsible for it.
Its action helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting. It can also block, or reduce stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting.
Grenil Tablet can be used for treating the slow passage of food in your gastrointestinal tract, generally associated with gastritis or diabetes. For people suffering from this condition, this medication can treat the symptoms of vomiting, nausea, bloating and feeling full. Apart from that, it can also prevent vomiting and nausea that is associated with Parkinson’s disease. This medication works by emptying your stomach quickly, reducing nausea.
The maximum dose that is recommended for adults is 4 tablets, in a severe migraine attack. The dose that would suit your body depends on your body weight, other medicines that you are currently taking and your health condition. Ensure that you take the medicine only in that amount as instructed by the doctor.
In case you miss a dose, you can take it later. However, do not take two doses together to make up for the previous one that has been missed. Overdose can cause disorientation, light-headedness, losing muscle or balance control or difficulty in talking.
You are advised not to take this medication if you have the following conditions:
- An allergy to the tablet or any other ingredient of this medicine
- Bleeding problems or blockage in your stomach or in the intestine
- Tumour in the pituitary gland
- Cardiac disease
- Incorrect levels of magnesium, potassium or calcium in the blood
- Severe/moderate liver impairment
The possible side effects of taking Grenil Tablet can be diarrhea, headache, migraine, dryness of the mouth or breast pain. These side effects are not very common and go away in a few days. If not, you can consult your doctor.
Grenil tablet is helpful in treating the below provided problems:
Tumor Of Pituitary Gland
How long is the duration of effect?The effect of this medicine lasts up to 6 hours.
What is the onset of action?The peak effect of this medicine can be observed within 30 to 60 minutes of administration.
Are there any pregnancy warnings?This medicine should not be used by pregnant women unless suggested by the doctor. It is yet not established that what type of effect does this medicine would cause to the fetus. Hence, it should only be consumed after proper consultation with the doctor.
Is it habit forming?No habit forming tendencies were reported.
Are there any breast-feeding warnings?Breastfeeding mothers should ignore this medicine as it may cause problems for the infant. Doctor consultation for proper evaluation of risks is highly recommended.
Is It safe with alcohol?It is unsafe to consume alcohol with this medicine.
Is it safe to drive while on this medicine?This medicine may affect the alertness of the patients. Thus it is advised to avoid driving while taking this medicine.
Does this affect kidney function?Caution must be taken in patients with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.
Does this affect liver function?Caution must be taken in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.
Below is the list of medicines, which have the same composition, strength and form as Grenil Tablet , and hence can be used as its substitute.
Are there any missed dose instructions?Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.
Are there any overdose instructions?Contact your doctor if an overdose is suspected. Symptoms of overdose may include drowsiness, agitation, and convulsions and may be more prevalent in infants and children. Immediate medical attention including gastric lavage may be required in severe cases.
This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. This in turn, facilitates gastric emptying and decreases small bowel transit time. And it selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
5-HIAA Urine TestYou may get a false-positive result for this test if you take this medicine.
Interaction with Medicine
Interaction with Food
Ques: What is Grenil tablet?
Ques: What is Grenil tablet used for?
Ques: What are the side effects of Grenil tablet?
Ques: Can I take a higher than the recommended dose of this medicine?
Ques: Can I get addicted to Grenil?
Ques: What is the recommended storage condition for grenil?
Ques: Can the use of Grenil cause damage to liver?
Ques: Should i use Grenil empty stomach, before food or after food?
Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:https://druginfo.nlm.nih.gov/drugportal/rn/57808-66-9
Domperidone 10mg Tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 23 April 2019]. Available from:https://www.medicines.org.uk/emc/product/556
Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:https://druginfo.nlm.nih.gov/drugportal/name/paracetamol
7 Select Acetaminophen- acetaminophen tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2017 [Cited 23 April 2019]. Available from:https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=168da31e-de62-4280-9c66-2b41d2d93c31
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