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Overview

Dapoxetine

Prescription vs.OTC: Prescription by Doctor required

Dapoxetine is a medication used to treat males for sexual dysfunction, such as premature ejaculation. It is also an antidepressant drug. You can also use this with or without alternatives like Kegel exercises, a balanced and healthy diet, and regular exercises. Decreasing your alcohol intake and ceasing of smoking of tobacco could also help in treating this condition.

The initial dose for this drug is 30 mg per day. Once started, you can increase the dosage gradually. The effectiveness of the drug will not be immediately visible; the results can be observed gradually over a period of months. Once you begin the medication, you must gradually stop taking this treatment after 4 to 6 months. Taking this medication over a longer or a prolonged period of time could cause cardiac problems or problems in your gastrointestinal tract. While this medicine is easily available over the counter, you are strongly advised to consult a psychiatrist before beginning to use this medication. You may also use Paroxetine or Duralast if required.

Possible side effects of this drug are drowsiness and sedation. Hence, you are advised to take this medicine at night, just before you go to bed. Do not use if allergic to it.

In addition to its intended effect, Dapoxetine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Is It safe with alcohol?
Duragain tablet may cause excessive drowsiness and calmness with alcohol.
Are there any pregnancy warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
You may feel sleepy, dizzy, faint, have difficulty concentrating and blurred vision while taking this medicine.\t
Does this affect kidney function?
Caution should be exercised with impaired Renal function.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Are there any missed dose instructions?
If you miss a dose of Dapoxetine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Below is the list of medicines, which contains Dapoxetine as ingredient
Fourrts India Laboratories Pvt Ltd
Hetero Drugs Ltd
Mankind Pharma Ltd
Akumentis Healthcare Ltd
Intas Pharmaceuticals Ltd
Fourrts India Laboratories Pvt Ltd
Aaura Care Pharmaceutical Pvt Ltd
Delvin Formulations Pvt Ltd
Alkem Laboratories Ltd
Intas Pharmaceuticals Ltd
Indoco Remedies Ltd
Akumentis Healthcare Ltd
Indoco Remedies Ltd
Akumentis Healthcare Ltd
Delvin Formulations Pvt Ltd
Hetero Drugs Ltd
R B Pharmaceuticals
UTH Healthcare
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Medicine
LINOWIN 2MG INJECTION
Rimarex 300Mg Capsule
GLI 2MG TABLET
CYBLEX 40MG TABLET
What are you using Dapoxetine for?
sexual dysfunction
Other
How much was the improvement?
Average
Excellent
Poor
How long did it take before seeing improvement?
Within 2 hours
Within a day
More than 2 days
Within 2 days
Within 6 hours
How frequently did you take this medicine?
Once a day
Not taking on daily level
Four times A Day
Thrice a day
Twice a day
How did you take this medicine?
With Food
With or without food
Empty stomach
What were the side effects of this medicine?
Other
Headache
Nausea
Dizziness
No Side Effects
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Dear sir. I am using dapoxetine 60 mg for prevent PE and I would like to take cialis pills along with dapoxetine. Is it ok?

MD - General Medicine
Sexologist, Nashik
Dear sir. I am using dapoxetine 60 mg for prevent PE and I would like to take cialis pills along with dapoxetine. Is ...
Cilalis is for ed. Do not go for self medication its habit forming. You r too young to such drugs try natural ways.

I have premature ejaculation problem, doctor proscribed me dapoxetine how long should I take dapoxetine.

MS Human Sexuality, M.Phil Clinical Psychology, PhD (Behaviour Modification), Certified In Treatment of Resistant Depression
Sexologist, Hyderabad
I have premature ejaculation problem, doctor proscribed me dapoxetine how long should I take dapoxetine.
You take it for about eithe weeks after which just take it on sos baismine and a half hour before sex. But my advice will be to get off the drug and not depend on it permanently. Best of luck.
3 people found this helpful

Does dapoxetine decrease my sexual interest. How can I overcome from it. I have take 6 times dapoxetine tablet. How can I make me to feel like before.

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Sexologist, Delhi
Does dapoxetine decrease my sexual interest. How can I overcome from it. I have take 6 times dapoxetine tablet. How c...
You are suffering from low desire sexual disorders. Don't ignore this problem. It may cause sexual disorder in the future. Maybe it's your initial stage so you shouldn't ignore this problem otherwise it will badly effect on your sexual life. We provide ayurvedic treatment of this problem. You can contact us at We will concern and later on, we can deliver medicines.

I use viagra, I want to know about the side effects of sildenafil citrate and dapoxetine tablets ?

Advanced Aesthetics
Ayurveda, Gulbarga
I use viagra, I want to know about the side effects of sildenafil citrate and dapoxetine tablets
?
Headaches and migraines flushing (redness) indigestion nausea (feeling sick) vomiting (being sick) a blocked or runny nose back pain vision disturbances muscle pain changes in your blood pressure dizziness headache pain in your penis urethral burning or bleeding for ayurvedic treatment consult privately.

How better dapoxetine or a climax spray helps in sex, is there any side effects?, kindly suggest how to use his..

MBBS, Diploma In Dermatology & Venerology & Leprosy (DDVL)
Dermatologist, Raigarh
How better dapoxetine or a climax spray helps in sex, is there any side effects?, kindly suggest how to use his..
ED Mostly medicines used to treat this problem aim at increasing blood flow towards penis but there may be some potentially serious side effects of these medicines. The patient may experience nasal congestion, dizziness, sleeplessness, headache, backache, and hot and cold flashes. Those who are already diagnosed with high or low BP, diabetes, or uncontrolled hepatitis should not take medicines recommended for erectile dysfunction. Other methods to treat the condition include erection inducing injections and testosterone implants but there are many side effects associated with these methods of treating the disease. These injections may cause painful acne, swollen gums, pain in penis, or breast enlargement. Mainly injections are known as Intracavernous drugs and suppositories are called Intraurethral medicines. Drugs prescribed for this purpose are usually taken a few minutes before intercourse and one is not allowed to use the drug more than once per day although the dosage depends on the type of the drug ,if you want medicine than , i will prescibe
4 people found this helpful

Popular Health Tips

Premature Ejaculation Treatment

Ph.D (Male Infertility), M.S (Infertility), D.G.L.S, D.R.C.O.G, C.Sc., D.M.R.D, M.B.B.S
Sexologist, Bangalore
Premature Ejaculation Treatment

Premature ejaculation - medicines:
You can take:

1. Dapoxetine 30 mg. Tab.
Trade names:
Duralast.
Dasutra.
Sustinex 
Dapox
Durlast
Ejalong
Kutub 
Take one tablet 1-3 hours before you have sex.
Side effects: 
Feeling dizzy or faint, and feeling sick. 
Drinking a full glass of water at the same time as taking the tablet can reduce these effects.

2. Paroxetine 12.5mg, one tablet after food for a month at night. 

The brand names:
Perolight 12.5 mg

Parocin cr 12.5 mg.
Side effects:
Vision changes;
Weakness,
Drowsiness,
Dizziness;
Sweating
Anxiety
Shaking;
Sleep problems (insomnia);
Loss of appetite, constipation;
Dry mouth,
Yawning; or.
Decreased sex drive, impotence or difficulty having an orgasm.

3. Lignocaine jelly (xylocaine) 2%:
Apply over glans penis (head of penis) 10 minutes prior to the intercourse to delay ejaculation. 
 
If medicines are not effective then, we can try other techniques.

32 people found this helpful

Medical Therapy For Premature Ejaculation!

MBBS, MCCEE, Fellowship in Sexual Medicine
Sexologist, Jaipur
Medical Therapy For Premature Ejaculation!

How to manage premature ejaculation - part 4, medical treatment options

As discussed earlier, premature ejaculation (pe) occurs when a man reaches the peak of sexual excitement and ejaculates before he wants it to happen. When pe interferes with the sexual pleasure of a man or his partner, it becomes a medical problem.

Several factors such as psychological problems (eg. Anxiety), penile hypersensitivity, habituation of quick sex / masturbation, alcohol abuse, hormonal imbalance (e. G. Thyroid problem), and even genetic problems may cause pe.

Medical (allopathic) therapy for pe treatment:

Drugs used for the management of pe reduce sensitivity and anxiety, improve blood flow or even affect some chemical mediators present in the brain. These classes of drugs include local anaesthetics, antidepressants, and phosphodiesterase 5 inhibitors.

Anaesthetic compounds were the first medical treatment proposed for pe management. They were applied topically to the surface of the skin. Lidocaine-prilocaine sprays or creams decrease the sensation of the penis and increase the time taken to ejaculate during vaginal penetration. These sprays / creams are applied 10 to 20 minutes prior to sexual activity. Side effects of topical agents include partial loss of sensation of the penis, absorption in vagina resulting in vaginal numbness and irritation.

Treatment medications include selective serotonin reuptake inhibitors (ssris), which interact with a receptor (5-ht2c) present in brain and increases the production of serotonin. They also help in reducing anxiety and depression associated with pe. Through this mechanism, they prolong the time to reach ejaculation.

Several ssris have increasingly become used as" off-label" for pe. Among the available ssris, paroxetine and dapoxetine are more beneficial with lesser side effects as compared to other ssris. These medications are associated with sexual side effects including decreased fertility and erectile dysfunction. Dapoxetine is a recent ssri which acts quickly and cleared rapidly from the body. Adverse effects with ssris are usually minor and include fatigue, mild nausea, loose stools and sweating. Other side effects may include decreased sexual urge and increased tendency to suicide, especially with long-term paroxetine.


Another potential treatment option for pe are classes of medications which increase the blood flow by dilating the blood vessels of the penile region and prolong the ejaculation time (phosphodiesterase 5 inhibitors). But a headache, dizziness, flushing, body aches associated with them have limited their use in pe.

At present, clinicians need to consider all treatment modalities when evaluating a man with pe, as each patient may respond differently and experience variable side effects. Additional and more effective therapies need to be developed having least side effects.

Ayurvedic therapy for pe treatment:

Vajikaran in Ayurveda is an important treatment modality which increases sexual capacity and improves health. In Sanskrit, vaji means horse, the symbol of sexual potency and performance thus vajikaran means producing a horse's vigor, particularly the animal's great capacity for sexual activity in the individual. Vajikaran therapy reenergizes all the seven dhatus (body elements) and restores equilibrium and health. It also offers a solution to minimize the shukra (sperm and ovum) defects.

There are many formulations which are used in vajikaran. Some of the commonly used formulations include vrihani gutika, vrishya gutika, vajikaranam ghritam and upatyakari shashtikadi gutika. Vrihani gutika is one of the potent formulations while vrishya gutika is highly potent aphrodisiac used in the treatment of pe. Vajikaranam ghritam enhances the strength of penis. Upatyakari shashtikadi gutika is useful for the enhancement of the fertility.

Also, chapdraprabha vati and kaunch pak are known to increase sexual vigor and semen consistency, thereby helping to prolong ejaculation time and sex pleasure. If you wish to discuss about any specific problem, you can consult a Sexologist.

5452 people found this helpful

How to Manage Premature Ejaculation? Medical Treatment Options

Bachelor of Ayurveda, Medicine & Surgery (BAMS), MS-Ayurveda
Sexologist, Delhi
How to Manage Premature Ejaculation? Medical Treatment Options

As discussed earlier, premature ejaculation (pe) occurs when a man reaches the peak of sexual excitement and ejaculates before he wants it to happen. When pe interferes with the sexual pleasure of a man or his partner, it becomes a medical problem.

Several factors such as psychological problems (eg. Anxiety), penile hypersensitivity, habituation of quick sex / masturbation, alcohol abuse, hormonal imbalance (e. G. Thyroid problem), and even genetic problems may cause pe.

Medical (allopathic) therapy for pe treatment:

Drugs used for the management of pe reduce sensitivity and anxiety, improve blood flow or even affect some chemical mediators present in the brain. These classes of drugs include local anaesthetics, antidepressants, and phosphodiesterase 5 inhibitors.

Anaesthetic compounds were the first medical treatment proposed for pe management. They were applied topically to the surface of the skin. Lidocaine-prilocaine sprays or creams decrease the sensation of the penis and increase the time taken to ejaculate during vaginal penetration. These sprays / creams are applied 10 to 20 minutes prior to sexual activity. Side effects of topical agents include partial loss of sensation of the penis, absorption in vagina resulting in vaginal numbness and irritation.

Treatment medications include selective serotonin reuptake inhibitors (ssris), which interact with a receptor (5-ht2c) present in brain and increases the production of serotonin. They also help in reducing anxiety and depression associated with pe. Through this mechanism, they prolong the time to reach ejaculation.

Several ssris have increasingly become used as" off-label" for pe. Among the available ssris, paroxetine and dapoxetine are more beneficial with lesser side effects as compared to other ssris. These medications are associated with sexual side effects including decreased fertility and erectile dysfunction. Dapoxetine is a recent ssri which acts quickly and cleared rapidly from the body. Adverse effects with ssris are usually minor and include fatigue, mild nausea, loose stools and sweating. Other side effects may include decreased sexual urge and increased tendency to suicide, especially with long-term paroxetine.


Another potential treatment option for pe are classes of medications which increase the blood flow by dilating the blood vessels of the penile region and prolong the ejaculation time (phosphodiesterase 5 inhibitors). But a headache, dizziness, flushing, body aches associated with them have limited their use in pe.

At present, clinicians need to consider all treatment modalities when evaluating a man with pe, as each patient may respond differently and experience variable side effects. Additional and more effective therapies need to be developed having least side effects.

Ayurvedic therapy for pe treatment:

Vajikaran in Ayurveda is an important treatment modality which increases sexual capacity and improves health. In Sanskrit, vaji means horse, the symbol of sexual potency and performance thus vajikaran means producing a horse's vigor, particularly the animal's great capacity for sexual activity in the individual. Vajikaran therapy reenergizes all the seven dhatus (body elements) and restores equilibrium and health. It also offers a solution to minimize the shukra (sperm and ovum) defects.

There are many formulations which are used in vajikaran. Some of the commonly used formulations include vrihani gutika, vrishya gutika, vajikaranam ghritam and upatyakari shashtikadi gutika. Vrihani gutika is one of the potent formulations while vrishya gutika is highly potent aphrodisiac used in the treatment of pe. Vajikaranam ghritam enhances the strength of penis. Upatyakari shashtikadi gutika is useful for the enhancement of the fertility.

Also, chapdraprabha vati and kaunch pak are known to increase sexual vigor and semen consistency, thereby helping to prolong ejaculation time and sex pleasure.

6 people found this helpful

Knowing Premature Ejaculation - PART 4: Treatment Options

MD-Pharmacology, MBBS
Sexologist, Delhi
Knowing Premature Ejaculation - PART 4: Treatment Options

How to manage premature ejaculation - part 4, medical treatment options

As discussed earlier, premature ejaculation (pe) occurs when a man reaches the peak of sexual excitement and ejaculates before he wants it to happen. When pe interferes with the sexual pleasure of a man or his partner, it becomes a medical problem.

Several factors such as psychological problems (eg. Anxiety), penile hypersensitivity, habituation of quick sex / masturbation, alcohol abuse, hormonal imbalance (e. G. Thyroid problem), and even genetic problems may cause pe.

Medical (allopathic) therapy for pe treatment:

Drugs used for the management of pe reduce sensitivity and anxiety, improve blood flow or even affect some chemical mediators present in the brain. These classes of drugs include local anaesthetics, antidepressants, and phosphodiesterase 5 inhibitors.

Anaesthetic compounds were the first medical treatment proposed for pe management. They were applied topically to the surface of the skin. Lidocaine-prilocaine sprays or creams decrease the sensation of the penis and increase the time taken to ejaculate during vaginal penetration. These sprays / creams are applied 10 to 20 minutes prior to sexual activity. Side effects of topical agents include partial loss of sensation of the penis, absorption in vagina resulting in vaginal numbness and irritation.

Treatment medications include selective serotonin reuptake inhibitors (ssris), which interact with a receptor (5-ht2c) present in brain and increases the production of serotonin. They also help in reducing anxiety and depression associated with pe. Through this mechanism, they prolong the time to reach ejaculation.

Several ssris have increasingly become used as" off-label" for pe. Among the available ssris, paroxetine and dapoxetine are more beneficial with lesser side effects as compared to other ssris. These medications are associated with sexual side effects including decreased fertility and erectile dysfunction. Dapoxetine is a recent ssri which acts quickly and cleared rapidly from the body. Adverse effects with ssris are usually minor and include fatigue, mild nausea, loose stools and sweating. Other side effects may include decreased sexual urge and increased tendency to suicide, especially with long-term paroxetine.


Another potential treatment option for pe are classes of medications which increase the blood flow by dilating the blood vessels of the penile region and prolong the ejaculation time (phosphodiesterase 5 inhibitors). But a headache, dizziness, flushing, body aches associated with them have limited their use in pe.

At present, clinicians need to consider all treatment modalities when evaluating a man with pe, as each patient may respond differently and experience variable side effects. Additional and more effective therapies need to be developed having least side effects.

Ayurvedic therapy for pe treatment:

Vajikaran in Ayurveda is an important treatment modality which increases sexual capacity and improves health. In Sanskrit, vaji means horse, the symbol of sexual potency and performance thus vajikaran means producing a horse's vigor, particularly the animal's great capacity for sexual activity in the individual. Vajikaran therapy reenergizes all the seven dhatus (body elements) and restores equilibrium and health. It also offers a solution to minimize the shukra (sperm and ovum) defects.

There are many formulations which are used in vajikaran. Some of the commonly used formulations include vrihani gutika, vrishya gutika, vajikaranam ghritam and upatyakari shashtikadi gutika. Vrihani gutika is one of the potent formulations while vrishya gutika is highly potent aphrodisiac used in the treatment of pe. Vajikaranam ghritam enhances the strength of penis. Upatyakari shashtikadi gutika is useful for the enhancement of the fertility.

Also, chapdraprabha vati and kaunch pak are known to increase sexual vigor and semen consistency, thereby helping to prolong ejaculation time and sex pleasure.

'consult'.

Related Tip: Knowing Premature Ejaculation - PART 3: Management and Techniques (Non-medical methods)

4014 people found this helpful

Premature Ejaculation: What Should You Know About It?

MD - Psychiatry, Diploma in Psychological Medicine, MBBS
Sexologist, Mumbai
Premature Ejaculation: What Should You Know About It?

My last article gave insight on the non-medical methods of controlling premature ejaculation Now, as a wrap up on this topic, I will highlight the options of medical treatments available for managing P.E. However, take it as a warning that you must consult your doctor before trying out any of these methods and medicines, because more often than not, such drugs and medicines have their side effects that can adversely bother your health.

By now we know that Premature ejaculation (PE) occurs when a man reaches peak of sexual excitement and ejaculates before he actually wants it to happen, thus, leaving his partner deprived of the sexual pleasure that she deserves. Even the most empathetic female partner would not like his man to leave her unsatisfied in bed.  Sooner or later this problem becomes a medical problem, reduces the warmth in their relationship.

Several factors including psychological problems such as anxiety; biological problem like penile hypersensitivity, hormonal imbalance (e.g. thyroid problem); behavioural problem like, habituation of quick sex/masturbation, etc may be held responsible for causing PE.

Medical (Allopathic) therapy for PE treatment:

Drugs used for managing premature ejaculation reduce sensitivity and anxiety, improve blood flow and even affect some chemical mediators present in the brain. These class of drugs include local anaesthetics, antidepressants and phosphodiesterase-5 inhibitors.

Anaesthetic compounds were the first medical treatment proposed for PE management. They were applied topically to the surface of skin. Lidocaine-prilocaine sprays or creams decrease the sensation of the penis and increase the time taken to ejaculate during vaginal penetration. These sprays/ creams are applied 10 to 20 minutes prior to sexual activity. Side effects of topical agents include partial loss of sensation of penis, absorption in vagina resulting in vaginal numbness and irritation.

Earlier agents like Alpha Amino Benzoate and Phenoxybenzamine were used to prolong duration of intercourse, but they were associated with severe side effects.

It has been found that Serotonin (a chemical in brain) levels were deficient in PE patients. Treatment medications include Selective Serotonin Reuptake Inhibitors (SSRIs), which interact with a receptor (5-HT2C) present in brain and increases the production of Serotonin. They also help in reducing anxiety and depression associated with PE. Through this mechanism, they prolong the time to reach ejaculation. Several SSRIs have increasingly become used as 'off-label' for PE.

Among the available SSRIs, Paroxetine-Dapoxetine is more beneficial with lesser side effects as compared to other SSRIs. These medications are associated with sexual side effects including decreased fertility and erectile dysfunction. Dapoxetine is a recent SSRI which acts quickly and cleared rapidly from the body. Adverse effects with SSRIs are usually minor and include fatigue, mild nausea, loose stools and sweating. Other side effects may include decreased sexual urge and increased tendency to suicide, especially with long-term use of Paroxetine.

Another potential medical treatment option for PE are class of medications which increase the blood flow by dilating the blood vessels of penile region and prolong the PE. But headache, dizziness, flushing, body-ache associated with them have limited their use in PE.

At present, clinicians need to consider all treatment modalities when evaluating a man with PE, as each patient may respond differently and experience variable side effects. Additional and more effective therapies need to be developed having least side effects.

Ayurvedic therapy for PE treatment:

Vajikaran in Ayurveda is an important treatment modality which increases sexual capacity and improves health. In Sanskrit, Vaji means horse, the symbol of sexual potency and performance thus Vajikaran means producing a horse's vigour, particularly the animal's great capacity for sexual activity in the individual. Vajikaran therapy reenergizes all the seven dhatus (body elements), and restores equilibrium and health. It also offers a solution to minimize the shukra (sperm and ovum) defects.

There are many formulations which are used in Vajikaran. Some of the commonly used formulations include Vrihani GutikaVrishya Gutika, Vajikaranam Ghritam and Upatyakari Shashtikadi Gutika.

Vrihani Gutika is one of the potent formulations while Vrishya Gutika is highly potent aphrodisiac used in treatment of PE. Vajikaranam Ghritam enhances the strength of penis. Upatyakari Shashtikadi Gutika is useful for the enhancement of the fertility.

Also, Chapdraprabha Vati and Kaunch Pak are known to increase sexual vigour and semen consistency helping in increase in sexual timing.

So, with this concluding article, I wrap up my knowledge and experience in treating patients suffering from premature ejaculation. Take care, and stay healthy!

In case you have a concern or query you can always consult an expert & get answers to your questions!

7131 people found this helpful

Table of Content

About Dapoxetine
What are the side effects of Dapoxetine?
Key highlights of Dapoxetine
What are the dosage instructions?
Medicines containing Dapoxetine
What are the interactions for Dapoxetine?